RESUMEN
PURPOSE: To analyze the results of treatment of eyelid xanthelasma (EX) with 70% trichloroacetic acid (TCA) with regard to efficacy, cosmetic appearance, patient satisfaction, and recurrence rate. METHODS: Twenty-four patients with EX of up to one third of the affected palpebral area were treated with 70% TCA. All patients were photographed at the start of treatment and 3 months after the last application. The recurrence rate was analyzed at the end of 6 months of treatment. RESULTS: The average number of applications of 70% TCA until the xanthelasma resolved was 1.5. Eleven patients (45.8%) had an excellent result, 8 (33.3%) a good result, and 5 (20.8%) had a satisfactory result. The most common complication was hypopigmentation (33.3%). All patients reported an improved final cosmetic result. Six patients (25%) treated with 70% TCA had a recurrence 6 months after treatment. CONCLUSIONS: The results of prospective treatment of 24 patients with EX with 70% TCA indicated that this is a simple and effective method, achieves a satisfactory cosmetic result, has an acceptable recurrence rate, and high patient satisfaction.
Asunto(s)
Cáusticos/administración & dosificación , Enfermedades de los Párpados/tratamiento farmacológico , Ácido Tricloroacético/uso terapéutico , Xantomatosis/tratamiento farmacológico , Adulto , Anciano , Relación Dosis-Respuesta a Droga , Enfermedades de los Párpados/patología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Soluciones Oftálmicas , Satisfacción del Paciente , Estudios Prospectivos , Resultado del Tratamiento , Xantomatosis/patologíaRESUMEN
PURPOSE: To describe the causes of congenital epiphora in patients with Down syndrome. METHODS: Retrospective study of 695 patients with congenital epiphora, of the Lacrimal Sector of the Department of Ophthalmology, São Paulo "Santa Casa", Brazil, between October 1998 and July 2005. This study analyzed: the main symptom of continuous epiphora or mucous discharge, which affected one or both eyes, since birth. Subjects were separated in to two groups: group A, with 30 patients with Down syndrome and group B, with 665 control patients. The lacrimal evaluation was performed by the throw irrigation test after general anesthesia. RESULTS: Both groups were statistically similar regarding age (p=0.07), sex (p=0.63) and race (p=0.68). Bilateral symptoms were more frequent in group A (p=0.0008). Anatomic obstruction of the lacrimal canal was present in 32.73% of group A and in 85.51% of group B (p<0.0001). CONCLUSIONS: The most frequent cause of congenital epiphora in Down syndrome is due to functional block of the lacrimal pump. Eyelid muscle hypotony and eyelid changes, common in Down syndrome, is the main hypothesis of lacrimal dysfunction, but further studies will be necessary for confirmation.
Asunto(s)
Síndrome de Down/complicaciones , Enfermedades del Aparato Lagrimal/congénito , Adolescente , Adulto , Estudios de Casos y Controles , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Enfermedades del Aparato Lagrimal/diagnóstico , Enfermedades del Aparato Lagrimal/etiología , Masculino , Estudios RetrospectivosRESUMEN
Relatou-se um caso de tumor maligno de nervo periférico (schwannoma) na órbita e revisou-se a literatura sobre essa rara lesäo