Ablation therapies for pancreatic cancer: an updated review.

While impressive strides have been made in the detection and management of numerous somatic malignancies over the past two decades, safe and effective treatments for pancreatic cancer have remained elusive. However, a number of emerging new therapies hold the promise of improving survival and quality of life for those stricken with the disease. Ablative therapies in particular, including those utilizing radiofrequency waves, microwaves, thermal energy, photodynamic energy and focused ultrasound waves provide an opportunity to target neoplasms while sparing healthy surrounding tissue. Paired with endoscopic ultrasound, these therapies offer a safe, effective and minimally invasive means to care of patients with otherwise inoperable tumors.

Endoscopic resolution of secondary complications in bariatric surgery.

Morbid obesity has become an epidemic in past few decades. It has become an important aspect of public health-focused issues due its impact on several chronic diseases, including diabetes and cardiovascular diseases. Consequently the number of bariatric surgeries have increased in the past few years due to improved techniques and devices. A multidisciplinary approach such as surgical intervention and diet modification has yielded effective and sustainable weight loss in morbidly obese patients. However, as with as surgical procedure, immediate and long term complications may occur after bariatric surgery. Approximately 5% to 10% of patients who undergo bariatric surgery develop early complications (also known as perioperative complications), those that appear within the first 30 days of surgery, and 9% to 25% show sign of problems after the initial 30 days (late complications). Complications of bariatric surgery are related to the type of procedure performed and this review will describe the most common complication and their endoscopic management.

Root and canal morphology of the mesiobuccal and distal roots of permanent first molars in a Kuwait population--a clinical study.

AIM: To identify the number of roots and canal configurations in permanent first molars of the indigenous Kuwaiti sub-population and compare them against a similar group of non-Kuwaiti population in different age groups and gender, and to determine the frequency of a second canal in the mesiobuccal root of maxillary first molars and distal root of mandibular first molars that could be located and treated in routine practice without using magnification or special lighting conditions. METHODOLOGY: A total of 220 permanent first molar teeth of patients scheduled for root canal treatment over a period of 1 year were included. Patients were identified and grouped according to their nationality as Kuwaiti and non-Kuwaiti (which included Filipinos, Indonesian Indians, Srilankans, Egyptians, Saudi Arabians and Syrians). In both nationality groups, patients were successively distributed into four groups based on their age. The first age group included patients below 20 years, the second 21-30 years, the third 31-40 years and the fourth were over 40 years. The first three groups comprised of 15 male and 15 female patients whilst the fourth group had 10 patients of each gender. Teeth with open apices, resorptions and calcification were excluded from the study. The teeth included were both clinically and radiographically examined for number of roots, the canal configuration and the presence of the additional mesiobuccal and distal canals and recorded. The simplified classification of canal configurations proposed by Weine was utilized. RESULTS: The incidence of a second canal in the mesiobuccal (MB) root of maxillary first molars and the distal root of mandibular first molars was not influenced significantly by nationality and gender. All the 110 maxillary first molars treated had three roots; 58% of MB root had one canal and 42% had two canals. The majority of the mesial roots had Weine type II canal configuration when the second mesiobuccal canal was present. All distobuccal and palatal roots had a single or type I canal configuration. Of the 110 mandibular first molars that were treated, 96% had two roots and 4% had three roots. When present, the third root was located either buccal or lingual to the main distal root. Overall 51% of the single distal roots had one canal whilst 49% had two canals. The mesial root frequently had a Weine type II canal configuration as did the distal root when a second canal was present. Pearson's correlation analysis of both molars revealed a significant (P < 0.05) negative correlation (r = -0.274, r = -0.144) between age and number of canals as well as the type of canal. CONCLUSIONS: The incidence of a second canal in distal roots of permanent mandibular first molars was 49% in the Kuwaiti population and this was similar to other Asian ethnic populations. Adopting modified access and troughing procedures revealed a 42% frequency of MB2 canals in maxillary first molars. The incidence of a second canal in both mesiobuccal roots of maxillary molars and distal roots of mandibular molars decreased significantly with age; no differences were noticed amongst the nationalities and gender studied. The possibility of extra roots should be anticipated in mandibular molars.