[The characteristics of the interferon system parameters in typologically different groups of patients with borderline mental disorders during treatment]. / Kharakteristika nekotorykh parametrov sistemy interferona v tipologicheski razlichnykh gruppakh bol'nykh s pogranichnymi psikhicheskimi rasstroistvami v protsesse lecheniia.

Lymphocyte gamma-interferon production and levels of serum interferon were studied in 94 patients with borderline psychiatric disorders on treatment. It was shown that parameters of interferon system in the acute disease period and their dynamics through the treatment depend on typological features of personality and initial level of interferon production. The patients with aggressive features of personality in acute disease exhibit significantly higher levels of serum interferon than those in patients with submissive features which drop after recovery. The same tendency occurred in hysterical patients (hystero-expressive and hystero-impressive types). These findings may be due to different reaction of immune system to chronic emotional stress in different types of personality.