RESUMEN
Parametrically Enabled Relaxation FIlters with Double and multiple Inversion (PERFIDI) is an experimental NMR/MRI technique devised to analyze samples/voxels characterized by multi-exponential longitudinal relaxation. It is based on a linear combination of NMR sequences with suitable preambles composed of inversion pulses. Given any standard NMR/MRI sequence, it permits one to modify it in a way which will attenuate, in a predictable manner and before data acquisition, signals arising from components with different r rates (r=1/T1). Consequently, it is possible to define relatively simple protocols to suppress and/or to quantify signals of different components. This article describes a simple way to construct low-pass, high-pass and band-pass PERFIDI filters. Experimental data are presented in which the method has been used to separate fat and water proton signals. We also present a novel protocol for very fast determination of the ratio between the fat signal and the total signal which avoids any time-consuming magnetization recovery multi-array data acquisition. The method has been validated also for MRI, producing well T1-contrasted images.
Asunto(s)
Tejido Adiposo/química , Algoritmos , Espectroscopía de Resonancia Magnética/métodos , Músculo Esquelético/química , Procesamiento de Señales Asistido por Computador , Agua/análisis , Animales , BovinosRESUMEN
Protocols were developed to apply Magnetic Resonance Imaging (MRI) to the dry-curing of Italian Parma ham. NMR relaxation analyses were performed on dry-cured hams at different processing stages to evaluate the ranges of variation of (1)H relaxation times T(1) and T(2) in representative ham muscle tissues, due to dehydration and salt uptake. MRI maps of the same ham sections were acquired, allowing T(1) and T(2) average values to be computed in selected Regions of Interest (ROI) inside muscle Semimembranosus, Semitendinosus and Biceps femoris. Chloride and moisture were determined by conventional chemical methods on the same ROIs, and MRI T(1) and T(1)/T(2) ratio were selected in a model (R(2)=0.90, P<0.05) fitting the salt content of the analysed muscle cores. Short Time Inversion Recovery (STIR) sequences were also applied to green and cured hams, but on fresh samples only, a bright image, displaying a clear separation between lean and fat tissue, was obtained.
RESUMEN
NMR relaxation time distributions, obtained with laboratory and portable devices, are utilized to characterize the pore-size distributions of building materials coming from the Roman remains of the Greek-Roman Theatre of Taormina. To validate the interpretation of relaxation data in terms of pore-size distribution, comparison of results from standard and in situ NMR experiments with results of the mercury intrusion porosimetry (MIP) has been made. Although the pore-size distributions can be obtained by NMR in terms of either longitudinal (T(1)) or transverse (T(2)) relaxation times distributions, the shorter duration of the T(2) measurement makes it, in principle, preferable, although the determination of T(2) distributions is not necessarily an easy alternative to finding T(1) distributions. Among other things, the T(1) distribution is almost independent of the inhomogeneity of the magnetic field, while the T(2) distribution is strongly influenced by it. This paper was aimed at answering two questions: what are the validity limits to interpret NMR data in terms of pore-size distributions and whether the portable device can successfully be applied as a non-destructive and non-invasive tool for in situ NMR analysis of building materials, particularly those of Cultural Heritage interest.
RESUMEN
Dual-energy mammographic imaging experimental tests have been performed using a compact dichromatic imaging system based on a conventional x-ray tube, a mosaic crystal, and a 384-strip silicon detector equipped with full-custom electronics with single photon counting capability. For simulating mammal tissue, a three-component phantom, made of Plexiglass, polyethylene, and water, has been used. Images have been collected with three different pairs of x-ray energies: 16-32 keV, 18-36 keV, and 20-40 keV. A Monte Carlo simulation of the experiment has also been carried out using the MCNP-4C transport code. The Alvarez-Macovski algorithm has been applied both to experimental and simulated data to remove the contrast between two of the phantom materials so as to enhance the visibility of the third one.
Asunto(s)
Mamografía/métodos , Intensificación de Imagen Radiográfica/métodos , Silicio , Algoritmos , Fenómenos Biofísicos , Biofisica , Femenino , Humanos , Mamografía/estadística & datos numéricos , Método de Montecarlo , Fantasmas de Imagen/estadística & datos numéricosRESUMEN
This work proposes a compact dichromatic imaging system for the application of the K-edge digital subtraction technique based on a conventional x-ray tube and a monochromator system. A quasi-monochromatic x-ray beam at the energy of iodine K-edge is produced by Bragg diffraction on a mosaic crystal. Two thin adjacent beams with energies that bracket the K-edge discontinuity are obtained from the diffracted beam by means of a proper collimation system. They are then detected using an array of Si detectors. A home-made phantom is used to study the image quality as a function of iodine concentration. Signal and signal-to-noise ratio analysis has also been performed. The results are compared with theoretical expectations.
Asunto(s)
Angiografía de Substracción Digital/métodos , Silicio/química , Rayos X , Medios de Contraste , Cristalización , Humanos , Procesamiento de Imagen Asistido por Computador , Yodo/farmacología , Modelos Estadísticos , Fantasmas de Imagen , Intensificación de Imagen Radiográfica , Técnica de Sustracción , Tecnología Radiológica , Tomografía Computarizada por Rayos X , AguaRESUMEN
Quantitative Relaxation Tomography in porous media furnishes maps of internal sections where each pixel represents T1 or T2 of water 1H in the corresponding voxel, so that quantitative information on the pore space structure can be obtained. The porosity can be determined at different length scales by correcting pixel by pixel the signal intensity for T2 decay. Moreover, on the basis of the distribution of T1, the microporosity fraction can be computed, as well as several voxel-average porosities. Since T1 and T2 encode different pieces of information, fusion image techniques can improve the characterization of the pore space, showing simultaneously, on the same image, maps of the two parameters. Examples are given of application to a water-saturated travertine core and to a pig femur. Different kinds of look-up tables were tried by varying two of the three dimensions of the HSV color space in such a way as to optimize both the T1 and T2 contrasts simultaneously.