RESUMEN
BACKGROUND: The Hernia Interest Group (HIG) of South Africa (SA), following the publication of their inguinal and ventral hernia guidelines (in 2015 and 2016 respectively), developed a hernia registry, the HIG(SA) hernia registry. METHODS: A retrospective analysis of the prospectively maintained HIG(SA) hernia registry from 1 February 2019 to 29 February 2020. Compliance to six recommendations made in the HIG(SA) ventral hernia guidelines were assessed in both the public and private healthcare systems. RESULTS: Three hundred and fifty-three ventral hernia repair cases were included in the study. Fifty-four per cent were private and 46% were public sector cases. Laparoscopic repair for patients with a BMI > 35 kg/m2 occurred in 38% of eligible cases and a minimum 5 cm of mesh overlap was achieved in 50% of cases. Overall, 80% of elective cases occurred in non-smokers; 97% of the intraperitoneal on-lay mesh (IPOM) repairs used composite mesh; 96% of ventral hernias with defects of larger than 2 cm and 95% of incisional hernias were repaired with mesh. Non-smokers undergoing repair numbered 72% in public and 85% in private practice, p = 0.01. CONCLUSION: Ventral hernia repair practices in SA facilities overall had good compliance to four out of the six HIG(SA) ventral hernia guidelines highlighted for the purposes of this study. The two guidelines that had poor compliance overall were 'laparoscopic repair for patients with a BMI of > 35 kg/m2' and 'ensuring a mesh overlap of 5 cm'. The public sector had higher rates of current smokers undergoing elective ventral hernia repair.
Asunto(s)
Hernia Ventral , Laparoscopía , Hernia Ventral/cirugía , Herniorrafia , Humanos , Opinión Pública , Recurrencia , Sistema de Registros , Estudios Retrospectivos , Sudáfrica , Mallas QuirúrgicasRESUMEN
PURPOSE: The purpose of this paper was to introduce a new registry in a developing country by describing the demographics, management and 30-day outcomes of patients undergoing ventral hernia repair in the public and private healthcare sectors of South Africa. METHODS: This study was a retrospective review of a prospectively maintained hernia registry from the 1st of February 2019 to 29th of February 2020. RESULTS: 353 ventral hernia repair cases were recorded of which 47% were incisional hernias and the remainder were primary hernias. The median age was 54 years with even distribution of males and females. Half of the patients were obese with a median BMI of 31 kg/m2. The private sector performed 190 cases (54%) and the public sector 163 cases (46%). The public sector had more current smokers undergoing elective repairs, 28% vs 15%, p = 0.01 and performed more emergency repair cases, 21% vs 8%, p < 0.01. The majority (89%) of hernias were repaired with mesh and one-third were repaired laparoscopically. 30 day follow up was obtained in 30% of cases, the private sector had better follow up rates (42% vs 14%). CONCLUSION: Participation in the HIG (SA) registry was low with poor follow up over the first year. Ongoing prospective data capture on the HIG (SA) hernia registry will continue to provide further insights into hernia repair practices in South Africa.
Asunto(s)
Hernia Ventral , Laparoscopía , Femenino , Sector de Atención de Salud , Hernia Ventral/epidemiología , Hernia Ventral/cirugía , Herniorrafia , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias , Estudios Prospectivos , Recurrencia , Sistema de Registros , Estudios Retrospectivos , Sudáfrica/epidemiología , Mallas QuirúrgicasRESUMEN
BACKGROUND: The National Institute for Health and Clinical Excellence (NICE) guidelines state that patients with dyspepsia as well as alarm symptoms, or those that are 55 years and older with new onset dyspepsia, urgently require an upper endoscopy within two weeks. The 'Be Clear on Cancer Campaign' launched by Public Health England estimated that 9% of deaths due to gastric and oesophageal cancers could have been avoided if the diagnosis was made at an earlier stage. Worcester Provincial Hospital (WPH) is a regional hospital in the Western Cape, South Africa, that due to resource constraints was unable to comply with these guidelines. An electronic endoscopy booking system was implemented in June 2014 to assist referring clinicians. OBJECTIVES: To evaluate the ability of the booking system to appropriately prioritise and accommodate clinically appropriate patients for an urgent gastroscopy within 2 weeks at WPH. METHODS: Retrospective analysis of patients booked for urgent gastroscopies using the online booking system at WPH from July 2014 to June 2017. RESULTS: A total of 1 589 gastroscopies were performed, with 1 085 (65%) categorised as urgent by the booking system algorithm, during the study period. The median (interquartile range) waiting time for urgent gastroscopies was 19 (8 - 31) days and 437 (40%) patients underwent a gastroscopy within the recommended 2-week period. Of the patients undergoing gastroscopy within 2 weeks, 87 (20%) were diagnosed with upper gastrointestinal malignancies and 73 (17%) had significant benign pathology (stricture or ulcer). A total of 150 malignancies were diagnosed in the urgent patients of whom 87 (58%) were scoped within 2 weeks. CONCLUSIONS: The volume of patients requiring urgent gastroscopy at WPH outstrips the available resources. The introduction of the online algorithm-based booking system was effective in prioritising patients. The use of this system facilitated a malignancy diagnosis rate which compares favourably with similar fast track endoscopy services in more developed countries.
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Citas y Horarios , Endoscopía Gastrointestinal , Sistemas de Registros Médicos Computarizados , Derivación y Consulta/organización & administración , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Algoritmos , Niño , Dispepsia/complicaciones , Endoscopía Gastrointestinal/estadística & datos numéricos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Programas Médicos Regionales , Estudios Retrospectivos , Sudáfrica , Listas de Espera , Adulto JovenRESUMEN
Ovine ulcerative balanitis and vulvitis in sheep of the Dorper breed has been observed in South Africa since 1979. Its aetiology has not been conclusively resolved, and there is some discrepancy in descriptions of its clinical features. In order to identify the pathogenic micro-organism/s that contribute to the occurrence of the disease, the microflora in the genital tracts of both clinically healthy and affected sheep were isolated and compared. Bacteriological examination of materials from affected and unaffected sheep resulted in the isolation of Arcanobacterium pyogenes from 44.2% and 17.2% of them respectively. This difference is statistically significant (P < 0.01). Seventy-four per cent of the isolates originated from severe clinical cases. Mycoplasmas were isolated from 49.3% of 116 clinically normal sheep and 78.2% of 104 affected sheep. There were significant differences in their rates of isolation in clinical groups (P < 0.05). Of all the mycoplasma isolates, Mycoplasma mycoides mycoides large colony variant (MmmLC) was isolated from 61.5% of clinically diseased sheep while 6.0% of the isolates were from apparently healthy animals (P < 0.05). The study threw light on the prevalence of mycoplasmas in the genital tract of apparently healthy sheep and, at the same time the identity of the mycoplasma pathogen associated with ulcerative balanitis and vulvitis was revealed. The findings of this investigation therefore confirmed the involvement of mycoplasma, particularly that of MmmLC large colony, in the disease in Dorper sheep in South Africa, and it was concluded that this microorganism is an important pathogen of balanitis and vulvitis in them. The study furthermore demonstrated a probable synergism between A. pyogenes and MmmLC. Finding these 2 organisms together occurred 53.4 times more frequently in the affected sheep than in the unaffected, which emphasises the probable multifactorial nature of the disease. The association between age and the presence of clinical signs was statistically significant. It was found that young sheep were more likely to have lesions than adult sheep. Clinical observations showed that the typical ulceration appears to be confined to the glans penis and lips of the vulva; no ulceration was observed on the shaft of the penis and prepuce or vaginal vestibule. In uncomplicated cases inflammation of the prepuce and vaginal vestibule is not a regular feature of the disease. Therefore the names ulcerative balanitis and vulvitis most accurately describe the nature of the disease in South Africa.
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Balanitis/veterinaria , Mycoplasma mycoides , Enfermedades de las Ovejas/etiología , Enfermedades de las Ovejas/patología , Vulvitis/veterinaria , Factores de Edad , Animales , Balanitis/epidemiología , Balanitis/etiología , Balanitis/patología , Infecciones por Corynebacterium/epidemiología , Infecciones por Corynebacterium/etiología , Infecciones por Corynebacterium/patología , Infecciones por Corynebacterium/veterinaria , Corynebacterium pyogenes/aislamiento & purificación , Femenino , Masculino , Mycoplasma , Infecciones por Mycoplasma/epidemiología , Infecciones por Mycoplasma/etiología , Infecciones por Mycoplasma/patología , Infecciones por Mycoplasma/veterinaria , Mycoplasma mycoides/aislamiento & purificación , Pleuroneumonía Contagiosa/epidemiología , Pleuroneumonía Contagiosa/etiología , Pleuroneumonía Contagiosa/patología , Ovinos , Enfermedades de las Ovejas/epidemiología , Sudáfrica/epidemiología , Vulvitis/epidemiología , Vulvitis/etiología , Vulvitis/patologíaRESUMEN
The in vitro activities of enrofloxacin, florfenicol, oxytetracycline and spiramycin were determined against field isolates of Mycoplasma mycoides mycoides large colony (MmmLC) by means of the broth microdilution technique. The minimum inhibitory concentrations (MICs) of these antimicrobial drugs were determined for a representative number of 10 isolates and 1 type strain. The susceptibility of Arcanobacterium pyogenes to enrofloxacin, oxytetracycline and tilmicosin was determined by means of an agar disk diffusion test. The MICs of enrofloxacin, florfenicol, oxytetracycline and spiramycin were within the ranges of 0.125-0.5, 1.0-2.0, 2.0-4.0 and 4.0-8.0 microg/ml, respectively. This study has shown that resistance of MmmLC against enrofloxacin, florfenicol, oxytetracycline and spiramycin was negligible. All the field strains of A. pyogenes that were tested were susceptible to enrofloxacin, oxytetracycline and tilmicosin with mean inhibition zones of 30.6, 42.3 and 35.8 mm, respectively. Although there is lack of data on in vivo efficacy and in vitro MIC or inhibition zone diameter breakpoints of these antimicrobial drugs for MmmLC, the MIC results indicate that these 4 classes of antimicrobial drugs should be effective in the treatment of ulcerative balanitis and vulvitis in sheep in South Africa.
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Antibacterianos/farmacología , Balanitis/veterinaria , Corynebacterium pyogenes/efectos de los fármacos , Mycoplasma mycoides/efectos de los fármacos , Enfermedades de las Ovejas/tratamiento farmacológico , Vulvitis/veterinaria , Animales , Balanitis/tratamiento farmacológico , Balanitis/microbiología , Recuento de Colonia Microbiana/veterinaria , Relación Dosis-Respuesta a Droga , Farmacorresistencia Bacteriana , Femenino , Masculino , Pruebas de Sensibilidad Microbiana/veterinaria , Ovinos , Enfermedades de las Ovejas/microbiología , Resultado del Tratamiento , Vulvitis/tratamiento farmacológico , Vulvitis/microbiologíaRESUMEN
The occurrence of severe lameness in adult African elephant bulls in a shrub Mopane (Colophospermum mopane) ecosystem was investigated. Large ulcers in the soles of at least one front foot were seen in each of the recorded cases. Microscopically, the lesion can be described as a severe, chronic-active, ulcerative, bacterial pododermatitis (complicated by hypersensitivity/septic vasculitis). A variety of bacteria were isolated from these lesions as well as from regional lymph nodes. Streptococcus agalactiae was the most consistent isolate, while Dichelobacter nodosus, the only organism known to be involved with foot disease in domestic ruminants, was isolated from two cases. Contributory factors such as body mass, portal of entry and origin of potential pathogens may have predisposed to the development of the lesions.
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Elefantes , Dermatosis del Pie/veterinaria , Úlcera del Pie/veterinaria , Animales , Elefantes/microbiología , Dermatosis del Pie/microbiología , Dermatosis del Pie/patología , Úlcera del Pie/microbiología , Úlcera del Pie/patología , MasculinoRESUMEN
The eyes of clinically healthy Simmentaler cattle and those affected by ophthalmia were sampled once a month over a continuous period of 12 months for bacterial, mycoplasmal and ureaplasmal infections. In total 478 eyes, representing from a clinical viewpoint 414 healthy and 64 affected eyes, were swabbed. Bacteria were isolated from 201 (48.6%) healthy eyes and 56 (87.5%) affected eyes. No bacteria were isolated from the remaining eyes. Eleven genera of bacteria were isolated from healthy eyes and 8 genera from affected eyes. The majority of isolates were classified in the genera Moraxella, Neisseria and Staphylococcus. Mycoplasmas were isolated from 247 (50.7%) healthy eyes and 27 (42.2%) affected eyes. No mycoplasmas were isolated from the remaining eyes. Ureaplasmas were not isolated from any animal. Eye-frequenting moths were collected on 3 occasions during the investigation and bacterial and mycoplasmal isolation techniques were performed on a total of 21 moths. Twelve different genera of bacteria, mostly Nocardia, Corynebacterium, Staphylococcus, Moraxella, and mycoplasmas were isolated from various eye-frequenting moths. Scanning electron microscopical studies of the proboscis of the moths showed it to contain various sensillae and short triangular denticles that could possibly cause damage to the mucous membranes of the eyes and predispose to ophthalmia in cattle.
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Enfermedades de los Bovinos/microbiología , Endoftalmitis/veterinaria , Ojo/microbiología , Mariposas Nocturnas/fisiología , Animales , Bacterias/aislamiento & purificación , Bovinos , Endoftalmitis/microbiología , Mariposas Nocturnas/ultraestructura , Fenómenos Fisiológicos Oculares , SudáfricaRESUMEN
An outbreak of granular vulvitis and ulcerative posthitis in 24-month-old virgin Bonsmara heifers and bulls is reported. Ureaplasma was isolated locally from all the clinically infected cattle. There was marked clinical improvement within 3 d of the commencement of a 5 d course of tylosin administered intramuscularly at 10 mg kg-1. Ureaplasma could not be cultured from the external genitalia of either heifers or bulls following clinical recovery. Details of the Ureaplasma culture media are given.
Asunto(s)
Enfermedades de los Bovinos/diagnóstico , Enfermedades de los Bovinos/tratamiento farmacológico , Infecciones por Ureaplasma/veterinaria , Animales , Bovinos , Femenino , Masculino , Tilosina/administración & dosificación , Ureaplasma/aislamiento & purificación , Infecciones por Ureaplasma/diagnóstico , Infecciones por Ureaplasma/terapiaRESUMEN
The immunity conferred by an A. pyogenes bacterin-toxoid was evaluated in sheep, using an intravenous challenge system. Three sheep were vaccinated and 3 served as controls. The vaccinated sheep were not protected against pyogenic conditions. High antitoxin levels were induced by vaccination but could not be associated with protection against infection. Antibacterial antibody levels elicited with initial vaccination dropped progressively with the 2nd and 3rd vaccinations. Nevertheless, these antibodies did not seem to be necessary for protection against A. pyogenes conditions.