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2.
Int J Cardiol ; 137(1): 72-4, 2009 Sep 11.
Artículo en Inglés | MEDLINE | ID: mdl-18676044

RESUMEN

BACKGROUND: Distinguishing physiological hypertrophy from hypertrophic cardiomyopathy in athletes remains difficult, but vital in view of the risk of sudden death under effort. NT-proBNP was previously reported to be usually normal in healthy athletes, but often elevated in case of hypertrophic cardiomyopathy. OBJECTIVES: To assess the interest of NT-proBNP in differential diagnosis of left ventricular hypertrophy in athletes. METHODS: NT-proBNP levels were measured at rest and after effort in trained athletes referred for suspectedly abnormal (>or=13 mm) left ventricular hypertrophy. RESULTS: 17 patients were included, 10 of whom were diagnosed with hypertrophic cardiomyopathy (group I) while the other 7 presented typical signs of athlete's heart (group II). NT-proBNP levels did not significantly differ between groups, whether at rest or after effort. NT-proBNP levels were, however, significantly elevated in 3 subjects in group I, while being consistently normal in group II. CONCLUSIONS: In active athletes presenting with ambiguous left ventricular hypertrophy, abnormal NT-proBNP levels indicate hypertrophic cardiomyopathy, whereas normal values are inconclusive.


Asunto(s)
Cardiomiopatía Hipertrófica/sangre , Péptido Natriurético Encefálico/sangre , Fragmentos de Péptidos/sangre , Precursores de Proteínas/sangre , Deportes/fisiología , Adulto , Biomarcadores/sangre , Cardiomiopatía Hipertrófica/diagnóstico , Humanos , Masculino , Adulto Joven
4.
Presse Med ; 34(2 Pt 1): 111-3, 2005 Jan 29.
Artículo en Francés | MEDLINE | ID: mdl-15687981

RESUMEN

INTRODUCTION: Septicaemia on endocardial pacemaker leads is very rare but the presentation is insidious and the prognosis very bad if all the implanted materiel is not completely removed. OBSERVATION: A 55 year-old woman presented three episodes of Staphylococcus epidermidis septicaemia in three years, after incomplete removal of the pacing system. Permanent cure was finally obtained after complete removal of the pacemaker material. COMMENT: Emphasis must be placed on the difficulty in diagnosing and treating such affections, their severity and also the interest of a certain number of prophylactic measures.


Asunto(s)
Bacteriemia/etiología , Infección Hospitalaria/etiología , Remoción de Dispositivos/efectos adversos , Marcapaso Artificial/efectos adversos , Infecciones Estafilocócicas/etiología , Antibacterianos/uso terapéutico , Astenia/microbiología , Bacteriemia/sangre , Bacteriemia/diagnóstico , Bacteriemia/prevención & control , Infección Hospitalaria/sangre , Infección Hospitalaria/diagnóstico , Infección Hospitalaria/prevención & control , Remoción de Dispositivos/instrumentación , Remoción de Dispositivos/métodos , Ecocardiografía Transesofágica , Femenino , Fiebre/microbiología , Humanos , Control de Infecciones/métodos , Persona de Mediana Edad , Pronóstico , Proteína C/metabolismo , Recurrencia , Infecciones Estafilocócicas/sangre , Infecciones Estafilocócicas/diagnóstico , Infecciones Estafilocócicas/prevención & control , Staphylococcus epidermidis , Resultado del Tratamiento
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