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1.
Ter Arkh ; 92(9): 108-124, 2020 Oct 14.
Artículo en Ruso | MEDLINE | ID: mdl-33346439

RESUMEN

The agreement of experts of the Eurasian Association of Therapists (EAT) discusses pathogenesis and treatment of COVID-19. Modern data on the characteristics of cardiovascular, kidney, respiratory damage in SARS-infected CoV-2 are presented. The tactics of managing patients initially having cardiovascular diseases, diabetes mellitus, chronic obstructive pulmonary disease, bronchial asthma, chronic kidney disease are discussed in detail. The article presents data on drug interaction of drugs.


Asunto(s)
Asma , COVID-19 , Diabetes Mellitus , Enfermedad Pulmonar Obstructiva Crónica , Humanos , SARS-CoV-2
2.
Tsitol Genet ; 12(4): 299-306, 1978.
Artículo en Ruso | MEDLINE | ID: mdl-705880

RESUMEN

The presence of ouabain at a concentration of 4.10(-4) M in the culture medium is shown to lead to cytophysiological and morphological alterations in the cells. The synthetic and mitotic activity of the cells is reduced after 6 hrs of the experiment. The ultrastructure of all cell organelles changed simultaneously with their metabolic activity. The dynamics of ultrastructural alterations of the cells was observed. However, changes caused by ouabain did not result in death of the cell.


Asunto(s)
Metabolismo/efectos de los fármacos , Mitosis/efectos de los fármacos , Organoides/efectos de los fármacos , Ouabaína/farmacología , Fosfatasa Ácida/metabolismo , Línea Celular , Núcleo Celular/efectos de los fármacos , Cromatina/efectos de los fármacos , ADN/biosíntesis , Aparato de Golgi/efectos de los fármacos , Leucina/metabolismo , Biosíntesis de Proteínas , ARN/biosíntesis , Succinato Deshidrogenasa/antagonistas & inhibidores , Timidina/metabolismo , Uridina/metabolismo
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