RESUMEN
AIM: This study evaluated the impact of the IL-1 genotype and smoking status on the prognosis and development of complications of osseointegrated implants. MATERIAL AND METHODS: The clinical charts of 180 consecutively admitted patients were analyzed with respect to the occurrence of biological complications in conjunction with oral implants. Biologic complications were defined as clinical conditions with suppuration from the peri-implant sulcus, development of a fistula or peri-implantitis with radiologic bone loss. All patients had received one or more ITI dental implants, which had been in function for at least 8 (range: 8-15) years. This patient population had received 292 implants. From these, 51 implants in 34 patients showed late (infectious) biologic complications, and 241 implants had survived without any biologic complications at all. RESULTS: Of the 180 patients, 53 were smokers, who were subdivided in a series of classes according to their intensity of smoking and 127 were never smokers. Sixty-four of 180 (36%) patients tested positive for the IL-1 genotype polymorphism. This prevalence corresponds to previous reports for the prevalence of European descent populations. The results for the non-smoking group indicated no significant correlation between implant complications and a positive IL-1 genotype. However, there was a clear association for heavy smokers between a positive IL-1 genotype and implant complications. 6 of 12 or half of the heavy smokers and IL-1 genotype-positive patients had either an implant failure, i.e. loss of implant, or a biologic complication during the follow-up period. CONCLUSIONS: These findings have led to the conclusion that there is a synergistic effect between a positive IL-1 genotype and smoking that puts dental implants at a significantly higher risk of developing biologic complications during function.
Asunto(s)
Implantes Dentales/efectos adversos , Fracaso de la Restauración Dental , Interleucina-1/genética , Oseointegración/genética , Fumar/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Pérdida de Hueso Alveolar/diagnóstico por imagen , Pérdida de Hueso Alveolar/etiología , Pérdida de Hueso Alveolar/genética , Fístula Dental/etiología , Implantación Dental Endoósea/métodos , Femenino , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Periodontitis/etiología , Polimorfismo Genético , Pronóstico , Radiografía , Fumar/genéticaRESUMEN
The ameloblastoma is a benign odontogenic tumor of epithelial origin. Histopathologically, it occurs in six patterns: plexiform, follicular, acanthomatous, granular cell, basal cell, and desmoplastic type. This report presents a rare case of an ameloblastoma in the maxillary sinus that consists of three types: follicular, plexiform, and acanthomatous. The diagnostic procedure, surgical therapy, and follow-up findings are described and discussed.