Asunto(s)
Infecciones del Sistema Respiratorio/tratamiento farmacológico , Salicilatos/efectos adversos , Convulsiones/tratamiento farmacológico , Ácido Valproico/efectos adversos , Virosis/tratamiento farmacológico , Enfermedad Aguda , Niño , Preescolar , Humanos , Lactante , Recién Nacido , Infecciones del Sistema Respiratorio/complicaciones , Salicilatos/uso terapéutico , Convulsiones/complicaciones , Ácido Valproico/uso terapéutico , Virosis/complicacionesRESUMEN
A possibility of construction of a mathematical model for current prognosing of aseptic meningitis incidence both for 2-4 months in advance and for the whole year has been demonstrated. The initial information consisted of the data on prevalence of enteroviruses in water objects as from May. Comparison of the actual and estimated incidence indicates that with the proposed model, up to 90.4% of the incidence of aseptic meningitis may be explained.
Asunto(s)
Simulación por Computador , Infecciones por Enterovirus/epidemiología , Meningitis Aséptica/epidemiología , Meningitis Viral/epidemiología , Meningitis/epidemiología , Microbiología del Agua , Infecciones por Enterovirus/etiología , Humanos , Incidencia , Meningitis Aséptica/etiología , Meningitis Viral/etiología , Pronóstico , Análisis de Regresión , Factores de TiempoAsunto(s)
Lesiones Encefálicas/sangre , Prostaglandinas/sangre , Adolescente , Niño , Preescolar , HumanosRESUMEN
The authors present the results of examining the plasma lipids in 62 children with an infectious neurotoxic syndrome. The children were suffering from acute respiratory viral infections, lobular pneumonia, or intestinal infections. Hyperlipidemia and dysphospholipidemia were revealed: the former was due primarily to a rise of the content of non-saturated fatty acids and triglycerides, and the latter to a drop of the lecithin and cephaline levels. These changes correlated with the disease gravity. No substantial differences in the plasma lipid spectrum were revealed in the children with the neurotoxicoses due to the acute respiratory infections, pneumonias, and intestinal infections, however, in the latter cases a more marked rise of the triglyceride content was noted.
Asunto(s)
Enfermedades Intestinales/complicaciones , Lípidos/sangre , Enfermedades del Sistema Nervioso/etiología , Infecciones del Sistema Respiratorio/complicaciones , Virosis/complicaciones , Preescolar , Femenino , Humanos , Lactante , Masculino , Enfermedades del Sistema Nervioso/sangre , Fosfolípidos/sangre , Neumonía/complicaciones , SíndromeRESUMEN
Lipids, lipoproteins and lipid peroxidation in the blood serum, erythrocyte membranes and CSF were examined in 110 patients (aged 1 month to 3 years) with infectious neurotoxicosis developed in the presence of acute respiratory viral infections, pneumonia and intestinal infection. The results obtained showed a considerable fall in the level of total phospholipids and in their individual fractions in the blood serum and erythrocyte membranes; and their elevation in the CSF as well as increased lipid peroxidation in the blood serum and in the CSF. Among the questions discussed is a possible involvement of upset metabolism of lipids and their peroxides in the pathogenesis of infectious-toxic impairments of the nervous system in children of early age. The questions of their correction with lipostabilizing agents are also reviewed.