[The renin-angiotensin system:implications, pathology, therapeutic possibilities, perspectives]. / Sistemul renina-angiotensina: implicatii în patologie, posibilitati terapeutice, perspective.

The renin-angiotensin system is initiate by numerous pathological situations which release the renal ischemia: heart failure, arterial hypertension, renal pathology with or without diabetes mellitus. Therapeutic possibilities in renin-angiotensin system control are offered by angiotensin-converting enzyme inhibitors, angiotensin II type-1 receptors antagonists, angiotensin converting enzyme inhibitors and neutral endopeptidase inhibitors and angiotensin II type 2 receptors agonists.

[The efficacy of electroversion in the treatment of tachyarrhythmia complications of the heart valves]. / Eficienta electroconversiei în tratamentul complicatiilor tahiaritmice la valvulari.

The results of electric cardioversion in the treatment of tachyarrhythmias in a series of 431 patients with valve diseases of the left heart admitted during the last 10 years are presented. Most patients presented atrial fibrillation (71.4%), the atrial flutter and paroxysmal tachycardia necessitating electric cardioversion in 24.5% and 4.1% of the cases, respectively. The restoration of sinusal rhythm was obtained in 90% of the cases, a single shock being delivered in most of them (74.5%). The patients' age, type of arrhythmia and the causal valvular heart disease did not influence the results, the essential factors of restoration and especially of maintaining the sinusal rhythm failure being the age of the valvular heart disease, the quality of atrial myocardium (which depends on the size of the enlargement and age of arrhythmia) and the association of a coronary or myocardial alcohol induced affection. The importance of estimating the resumption of atrial mechanic activity is underlined. The "regulation" embolism was rare (5 cases), while an embolism occurring during the preparation period raises the possibility of a possible coincidence between the embolic accident and the recurrence of atrial mechanical systole after electric cardioversion.