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2.
J Med Virol ; 43(1): 1-4, 1994 May.
Artículo en Inglés | MEDLINE | ID: mdl-7521898

RESUMEN

The prevalence of anti-HCV was determined in 1,309 leprosy patients and a control group of 1,469 subjects from 6 sub-Saharan African countries and the Yemen. Sera found positive by an initial second generation ELISA were subjected to 3 additional confirmatory tests. The anti-HCV prevalence in leprosy patients (7.1%) was significantly higher than in the control group (2.6%). HCV seroprevalence increased with age in both the control and leprosy groups. No statistically significant difference could be found between anti-HCV prevalence and the several clinical forms of leprosy among patients. The results of this study indicate a high degree of exposure or chronic carriage of hepatitis C among leprosy patients.


Asunto(s)
Anticuerpos Antihepatitis/sangre , Hepatitis C/epidemiología , Lepra/complicaciones , Adulto , África/epidemiología , Factores de Edad , Ensayo de Inmunoadsorción Enzimática , Hepacivirus , Hepatitis C/complicaciones , Anticuerpos contra la Hepatitis C , Humanos , Técnicas para Inmunoenzimas , Persona de Mediana Edad , Prevalencia , Yemen/epidemiología
3.
J Med Virol ; 34(3): 194-8, 1991 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-1655969

RESUMEN

The prevalence of HHV-6 IgG was studied in 11 different countries across several continents: Morocco, Burkina-Faso, Congo, Ivory Coast, Mali, Niger, Senegal, Togo, Ecuador, Martinique, and France. The study group consisted of 550 pregnant women, representative of the general adult population in each country. Antibodies were detected by immunofluorescence assay on HSB-2 cells infected with HHV-6. Each serum was tested at nine dilutions (1:20 to 1:5,120), sera greater than or equal to 20 being considered positive. For the negative antigen control, we used mock-infected HSB-2 cells. Great differences were seen between separate areas: Morocco showed both low prevalence (20%) and a low geometric mean titer (12), whereas sub-Saharan Africa displayed high prevalences (60% to 90%) and variable geometric mean titers (34 to 229). This study revealed a prevalence of 92% for Ecuador, significantly higher than the prevalence for Martinique (50%), yet both countries had very low antibody titers compared with those found in Africa. The prevalence in France (76%) was similar to previous results from other European countries.


Asunto(s)
Infecciones por Herpesviridae/epidemiología , Herpesvirus Humano 6/inmunología , Adulto , África/epidemiología , Anticuerpos Antivirales/sangre , Ecuador/epidemiología , Femenino , Francia/epidemiología , Infecciones por Herpesviridae/sangre , Humanos , Inmunoglobulina G/sangre , Martinica/epidemiología , Embarazo
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