RESUMEN
Purpura fulminans features the sudden onset of large rapidly-spreading areas of hemorrhagic skin necrosis. This is followed by a disseminated intravascular coagulopathy with consecutive consumption of anticoagulant factors. Patients with severe disease in whom therapy is delayed often develop shock with a poor prognosis.The mortality rate is about 30-40%. An elderly women developed purpura fulminans after a respiratory infection. Prompt diagnosis before shock symptoms had started was instrumental in producing a favorable clinical course.
Asunto(s)
Púrpura Fulminante/diagnóstico , Púrpura Fulminante/etiología , Infecciones del Sistema Respiratorio/complicaciones , Infecciones del Sistema Respiratorio/diagnóstico , Anciano , Femenino , HumanosRESUMEN
In Germany Fuchs syndrome is used to describe a variant of erythema multiforme majus which mainly involves the mucosal surfaces. As the skin may be completely unaffected, it is an under-recognized diagnosis and often difficult to confirm. Clinical features involve erythema, erosions and ulcerations of the oral mucosa. In most cases there is severe conjunctivitis and sometimes the genital mucosa is involved. Most cases of Fuchs syndrome are triggered by infections; herpes simplex virus and Mycoplasma pneumoniae are the most common causes. We describe two women presenting with Fuchs syndrome after respiratory illness caused by Mycoplasma pneumoniae.
Asunto(s)
Corticoesteroides/uso terapéutico , Antibacterianos/uso terapéutico , Eritema Multiforme/diagnóstico , Eritema Multiforme/tratamiento farmacológico , Neumonía por Mycoplasma/diagnóstico , Neumonía por Mycoplasma/tratamiento farmacológico , Adulto , Eritema Multiforme/complicaciones , Femenino , Humanos , Neumonía por Mycoplasma/complicaciones , Resultado del TratamientoAsunto(s)
Dípteros , Dermatosis Facial/diagnóstico , Dermatosis Facial/parasitología , Miasis/diagnóstico , Miasis/parasitología , Enfermedades Cutáneas Parasitarias/diagnóstico , Enfermedades Cutáneas Parasitarias/parasitología , Animales , Diagnóstico Diferencial , Humanos , Larva , Masculino , Persona de Mediana EdadRESUMEN
Decorative tattoos have become very popular. As a result, a higher number of hypersensitivity reactions are seen, caused by the mostly undeclared tattoo dyes. If local and intralesional therapy with corticosteroids is not effective, total excision was formerly considered the best approach. Selective laser therapy offers an alternative approach for removing the offending pigment. Case reports are used to illustrate the individual treatment options for removal of tattoos.
Asunto(s)
Corticoesteroides/administración & dosificación , Colorantes/efectos adversos , Fármacos Dermatológicos/administración & dosificación , Hipersensibilidad/etiología , Hipersensibilidad/terapia , Terapia por Luz de Baja Intensidad/métodos , Tatuaje/efectos adversos , Adulto , Femenino , Humanos , Masculino , Guías de Práctica Clínica como Asunto , Pautas de la Práctica en MedicinaRESUMEN
Leflunomide is a disease-modifying antirheumatic drug for the treatment of active rheumatoid arthritis and psoriatic arthritis. Skin ulcerations are not listed as a side effect for this drug, and there has been only one case report on leflunomide associated skin ulcerations. We report on two females, 59 and 63 years old respectively, who were treated with leflunomide for rheumatoid arthritis and subsequently developed severe skin ulcerations. After discontinuation of the drug the skin ulcerations healed complete even if very slowly.
