[Zollinger-Ellison syndrome in children caused by hyperplasia of antral gastrin cells]. / Syndrome de Zollinger-Ellison chez l'enfant par hyperplasie des cellules à gastrine antrales.

A case of Zollinger-Ellison due to hyperplasia of antral gastrin cells in a 11 year-old child is reported. Only 49 cases of this syndrome in children have been published. The diagnosis (gastrin stimulation test, immunohistochemical detection of endocrine cells and therapeutic strategy are outlined).

[Study of the effectiveness of tiapride on psychic disorders in alcoholics]. / Etude de l'effeicacité du tiapride sur les troubles psychiques de l'alcoolique.

The effectiveness of tiapride on psychic disorders was studied in 30 chronic alcoholics by assessing four parameters: sleep disturbances, mood disorders, conduct disturbances, and tremor. In a daily dosage of 600 to 900 mg tiapride proved particularly effective on insomnia, anxiety, passivity and tremor, without adverse side-effects. This drug seems useful for controlling psychic disorders in alcoholics and for motivating acceptance of a detoxification program.

[Genetic deficiency of thyroxin-binding protein in 4 members of a family (author's transl)]. / Déficit génétique en globuline fixant la thyroxine chez quatre membres d'une famille.

Four members of the same family (2 male and 2 female) with normal thyroid function were found to have decreased total T3 and total T4, elevated response to the T3 test and low free thyroxin index. Such biological changes result from a deficiency in carrier protein and should be distinguished from nearly similar abnormalities observed in low T3 syndrome and hypothyroidism. Whilst gonosomal transmission through the X chromosome of thyroxin-binding protein deficiency seems well established, our findings show that another mechanism, i.e. dominant autosomal heredity, is practically certain.

[Chronic hepatitis in sex linked agammaglobulinemia. One case (author's transl)]. / Hépatite chronique au cours d'une agammaglobulinémie liée au sexe. Une observation.

The authors report the case of a 21 years old man, with sex-linked agammaglobulinemia, who presents a presumed viral hepatitis, followed two years. The evolution, does yet fear a progressive cirrhosis. About this report and analysis of literature, frequency, evolution and pathophysiologic hypothesis, particularly the lymphocyte T role, are also discussed as the problem of hepatitis prevention of these subjects, who receive gammaglobulin injections.