RESUMEN
Chelating chiral diphosphines are often used as ligands of organometallic complexes. However monophosphines, or more generally ligands with one phosphorus linked to one or several heteroatom, may also be useful. This review gives the main results obtained in that area, by considering the classes of monodentate chiral ligands bearing one P(III) atom and involved in asymmetric catalysis with organometallic complexes.
Asunto(s)
Compuestos Organometálicos/química , Fosfinas/química , Catálisis , Ligandos , EstereoisomerismoRESUMEN
Kinetic resolution of 2-hydroxyalkyldiphenylphosphines 4 by acylation with isopropenyl acetate was carried out under rabbit gastric lipase (RGL) catalysis to give optically active 4 and the corresponding acetate, the enantioselectivity factors E ranging from 10 to 20. 1-(2-Naphthyl)ethanol and 2-[N-(ethoxycarbonyl)amino]1-butanol 7 were also resolved.
