Multiple primary malignant neoplasms: a case of colonic adenocarcinoma and non-Hodgkin's lymphoma on a background of ulcerative colitis.

The presence of an adenocarcinoma and non-Hodgkin's lymphoma in an individual is an uncommon finding. In this case report, we discuss the case of an elderly man presenting with a synchronous moderately differentiated colonic adenocarcinoma alongside a distal ileal extranodal marginal zone lymphoma, on a background of ulcerative colitis. He underwent an elective open panproctocolectomy with an end ileostomy for the management of his malignancy.

Multiple primary malignant neoplasms: a case of colonic adenocarcinoma and non-Hodgkin's lymphoma on a background of ulcerative colitis.

The presence of an adenocarcinoma and non-Hodgkin's lymphoma in an individual is an uncommon finding. In this case report, we discuss the case of an elderly man presenting with a synchronous moderately differentiated colonic adenocarcinoma alongside a distal ileal extranodal marginal zone lymphoma, on a background of ulcerative colitis. He underwent an elective open panproctocolectomy with an end ileostomy for the management of his malignancy.

Effect of tricainemethanesulfonate (MS222), clove oil and electro-anaesthesia on respiratory burst activity in whole blood and serum alternative complement response in rainbow trout (Oncorhynchus mykiss), during the narcosis stage.

There is a little available information on the suppressive effect of anaesthesia on immune response in fish, especially electro-anaesthesia. In the present study, two anaesthetics, MS222 (50 ppm), clove oil (25 ppm), and electro-anaesthesia were tested in rainbow trout (Oncorhynchus mykiss) during the narcosis stage in order to observe their effects on the innate immune system. The results showed that electro-anaesthesia reduces light emission in chemiluminescence assay both 1 and 24 h post anaesthesia. Clove oil and MS222 decreased light emission 24 h post anaesthesia. In addition, clove oil, MS222 and electro-anaesthesia had no effect on alternative complement (ACH50) response. From the perspective of aquaculture practice, these data show that the type of anaesthesia should be taken into account to avoid possible immunosuppression in rainbow trout.

Use of mini-monoka stents for punctal/canalicular stenosis.

BACKGROUND: Proximal lacrimal system stenosis may cause debilitating epiphora and recurrent ocular infections. Mini-monoka stents are primarily used in the management of canalicular lacerations. Evidence regarding their use to treat punctal/canalicular stenosis is sparse. Compared with dacryocystorhinostomy, a punctocanaliculoplasty with mini-monoka stenting is quicker, less invasive with reduced postoperative complications/recovery time. AIMS: To assess the effectiveness of mini-monoka punctocanaliculoplasty for treatment of punctal/canalicular stenosis. METHODS: A retrospective case note analysis was performed on 77 consecutive patients (123 eyes). RESULTS: 73% of eyes had punctal stenosis, 72% had canalicular stenosis; 46% had a combination of the above. 20% had some degree of lid laxity and 29% had nasolacrimal duct stenosis. 101 eyes (82%) had significant improvement in symptoms and were discharged without further intervention. Excluding the patients with structural comorbidity the success rate improved to 88%. CONCLUSIONS: Mini-monoka punctocanaliculoplasty is an effective, safe, simple and relatively non-invasive treatment strategy for the management of epiphora secondary to punctal and/or canalicular stenosis.

Determination of normal values of some blood serum enzymes in Acipenser stellatus Pallas.

Hematological studies on fishes have assumed greater significance due to the increasing emphasis on pisciculture and greater awareness of the pollution of natural water resources. Such studies have generally been used as an effective and sensitive index to monitor physiological and pathological changes in fishes, especially in the management of endangered species. This study was undertaken to establish a reference range for six important blood serum enzymes. Serum samples of 40 Acipenser stellatus (20 female and 20 male) were analyzed, and serum enzyme values were determined. The reference ranges for the total samples and also for each sex were determined. The activities of measured enzymes in serum were: aspartate aminotransferase (AST) 265.60 +/- 56.55 IU/l, alanine aminotransferase (ALT) 5.65 +/- 1.18 IU/l, acid phosphatase (ACP) 15.63 +/- 2.59 IU/l, lactate dehydrogenase (LDH) 2007.15 +/- 521.97 IU/l, creatine kinase (CK) 6,596.05 +/- 1,807.19 IU/l, and alkaline phosphatase (ALP) 69.05 +/- 13.04 IU/l. There were significant differences between male and female fish in terms of AST and CK activity (P < 0.05). These may be related to the season of sampling and changing physiological cycles during spawning during which period the sexual hormones and stress are more obvious. However, there were no differences in the activity of ALP, ACP, LDH, and ALT between sexes. The correlations between measured enzymes were also determined.