[Efficacy and perspective of application of preparation based on hydrogel and xerogel of methyl-silicic acid in patients with the intestinal malignancy]. / Efektivnist' ta perspektyvy zastosuvannia preparativ na osnovi hidroheliu ta kseroheliu metylkremniievoï kysloty u khvorykh iz zloiakisnym novoutvorenniam travnoho kanalu.

There was studied the influence of medicinal preparations, created on the base of methylsiliconorganic matrix, on immediate and late follow-up result of treatment of more than 2000 patients with the digestive channel malignancy. High efficacy of application in complex of preoperative preparation of immobilized antibiotics and cytostatics, enterosorpent enterosgel for the purulent-inflammatory complications prophylaxis, lowering of bilirubin level in tumoral obturative jaundice, and in intraoperative usage for the tumor and metastases recurrences prophylaxis.

[The ways of the efficacy raising in surgical treatment of patients with colonic cancer]. / Shliakhy pidvyshchennia efektyvnosti khirurhichnoho likuvannia khvorykh na rak obodovoï kyshky.

The indications extension for the radical surgical intervention conduction in elderly and senile patients and with locally spreading colonic cancer had promoted the result of their treatment improvement.

[Primary multiple malignant tumors of the stomach and colon]. / Pervichno-mnozhestvennye zlokachestvennye opukholi zheludka i tolstoi kishki.

Experience of diagnosis and treatment of primarily-multiple gastric cancer, combined with malignant colonic tumors in 27 patients was summarized. One-stage combined radical treatment of the patients is the most effective one.

[The clinical and biochemical characteristics of the status of stomach cancer patients who were exposed to ionizing radiation as a result of the accident at the Chernobyl Atomic Electric Power Station]. / Klinicheskie i biokhimicheskie osobennosti statusa bol'nykh rakom zheludka, podvergshikhsia vozdeistviiu ioniziruiushchego izlucheniia v rezul'tate avarii na ChAES.

As many as 208 patients with carcinoma of the stomach were examined, with 98 of these, having been victims of Chernobyl accident. It has been established that in spite of the fact that the clinical picture was practically identical in both case groups those patients having been exposed to mixed radiation demonstrated more clearly manifest endogenous intoxication, impairement of erythrocytic membrane function, which fact calls correction of these changes in the preoperative period.

[The use of ceruloplasmin in combination with adjuvant polychemotherapy in stomach cancer]. / Primenenie tseruloplazmina v sochetanii s ad''iuvantnoi polikhimioterapiei pri rake zheludke.

Ceruloplasmin as a modulator was used for the first time in the clinical practice in 30 patients with gastric cancer in the course of postoperative intraabdominal adjuvant chemotherapy. It was established that ceruloplasmin was well tolerated by the patients and its use during polychemotherapy is accompanied by normalization of the levels of natural ceruloplasmin and iron in the blood serum that are usually reduced in patients with gastric cancer, reduces activation of lipid peroxidation and improves the course of postoperative period. Ceruloplasmin possesses a week immunomodulating action in polychemotherapy which is expressed in the increase of the percentage content of T-lymphocytes. Use of ceruloplasmin tended to improve the functional state of the cardiovascular system.

[Intensive preoperative gamma teletherapy combined with endogenous interferon induction in the treatment of stomach cancer]. / Intensivnaia predoperatsionnaia telegammaterapiia v sochetanii s induktsiei éndogennogo interferona pri lechenii raka zheludka.

The authors analyze results of combined treatment of 72 patients using preoperative intensive gamma teletherapy. Increase of 4-year survival was observed only in patients showing no regional metastases and equalled 18.7%. The authors worked out a method of preoperative radiation treatment against the background of induction of endogenous interferon by curantyl. The course of radiation therapy was carried out in association with a 2-3 times increase of the interferon levels in the blood and was accompanied by a reduction of the immunodepressive effect of gamma teletherapy on the body.

[Combination treatment of cancer of the stomach using preoperative telegammatherapy in combination with local SHF-hyperthermia]. / Kombinirovannoe lechenie raka zheludka s predoperatsionnoi telegammaterapiei v sochetanii s lokal'noi SVCh-gipertermiei.

The immediate and long-term results of treatment of 178 patients with gastric cancer, who underwent before surgery intensive telegammatherapy in combination with local SHF-hyperthermia, and without it, were studied. The total focal dosage was 20 Gy, temperature on the surface of a tumour reached 41-43 degrees C. At the late period, the increase in survival of the patients, who had no lesions of the regional lymphatic nodes was noted. In patients with regional metastases, the reverse effect was observed.

[Etiology, clinical picture, and diagnosis of postoperative peritonitis in rectal cancer]. / Prichiny, klinika i diagnostika posleoperatsionnogo peritonita pri rake priamoi kishki.

Under analysis were 40 case histories and records of dissections of patients dead of diffuse peritonitis after operations for rectum cancer. It was established that in 1/3 of observations technical defects were responsible for peritonitis. Measures for the prevention of peritonitis are proposed when infection in the abdominal cavity is revealed during operation. An atypical course of peritonitis, not pronounced signs of pathological abdominal cavity results in diagnostic errors. Diagnosis of cardiovascular insufficiency is established in most cases. Peritonitis in patients treated with the use of preoperative irradiation is characterized by the inert course without leukocytosis in many cases. The main efforts should be directed to prophylaxis, i. e. an improvement of the operation technique, struggle against hospital infections, suppression of the microbial flora in the abdominal cavity which appears due to technical errors during surgery.