[Investigations on the stability of therapeutic drugs derived from imidazole. XII. Qualitative and quantitative stability evaluation of phentolamine hydrochloride solutions]. / Badania trwalosci srodków leczniczychpochodnych imidazoliny.XII. Jakosciowa i ilosciowa ocena trwalosci roztworów chlorowodorku fentolaminy.

Hydrolysis of phentolamine hydrochloride in aqueous solutions, and at pH 1.0 and pH 8.0 was studied by means of thin-layer chromatography. A spectrophotometric method for quantitative assessment of phentolamine hydrochloride hydrolysis has been elaborated, and thermodynamic parameters of this reaction were determined.