RESUMEN
PURPOSE: To study the surgically induced astigmatism (SIA) in combined phacoemulsification and vitrectomy, and compare with that when either procedure is performed alone. METHODS: This is a prospective comparative interventional trial comprising of 60 eyes of 60 consecutive patients with cataract and/or vitreo-retinal pathology. They were divided equally into three groups based on the type of procedure: Group A, phacoemulsification alone group, using a 3.0-3.2 mm wide unsutured sclero-corneal tunnel incision at 1.0 mm post-limbus at 10 o'clock; Group B, par plana vitrectomy alone group, using three sclerotomies at 3.5 mm post-limbus at 2, 8, and 10 o'clock (right eye) or at 2, 4, and 10 o'clock (left eye) positions; and Group C, combined phacoemulsification and pars plana vitrectomy group. Main outcome measures were the amplitude (K-induced) and the axis of SIA calculated by rectangular coordinate method using the Holladay-Cravy-Koch formula. RESULTS: The mean K-induced amplitudes were 0.19+/-0.14 D, 0.17+/-0.11 D, and 0.23+/-0.19 D for groups A, B, and C, respectively. The range of K-induced amplitudes for the entire cohort was 0.00-0.77 D. No overall statistically significant differences in the pre- and postoperative topographic astigmatism amplitudes and the K-induced between groups A, B, and C were found (all P>0.05). Minor shifts, of doubtful clinical significance, in the axes of SIA were present. CONCLUSIONS: Combined phacoemulsification and pars plana vitrectomy does not induce significant astigmatic change per se, and its amount is similar to that when either procedure is performed alone.
Asunto(s)
Astigmatismo/etiología , Facoemulsificación/efectos adversos , Vitrectomía/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Topografía de la Córnea/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Facoemulsificación/métodos , Estudios Prospectivos , Resultado del Tratamiento , Vitrectomía/métodos , Adulto JovenRESUMEN
Topical chloramphenicol has been widely used in the treatment and prevention of superficial eye infections due to its broad spectrum of activity and low cost. The use of this drug has decreased considerably in the United States since the first case of aplastic anaemia associated with topical chloramphenicol was reported in the 1960s. This medication, however, is still widely used in many other countries. This paper evaluates the evidence for and against the use of topical chloramphenicol in ocular diseases.
