An epidural brain abscess and thrombus in the superior sagittal sinus in a 12 year-old with sinusitis.

BACKGROUND: Upper respiratory infections can be complicated by acute bacterial sinusitis in pediatric patients, and usually resolve with antibiotic therapy (DeMuri and Wald, 2011). However, intracranial complications such as: epidural abscess, meningitis and more rarely cerebral sinus venous thrombosis (CSVT) can occur (Germiller et al., 2006). We report an unusual case of sinusitis complicated by an epidural abscess and later a CSVT in a young previously healthy patient. CASE DESCRIPTION: A 12-year-old female presented to the emergency department with a 9-day history of headaches and a 3-day history of fevers, rigors, nasal congestion and nonproductive cough. She later tested positive for Covid-19. CT and MRI showed extensive paranasal sinus disease and a right frontal epidural collection. MRV showed no sinovenous thrombosis. Washout and burr hole drainage alongside endoscopic sinus surgery was completed and post-op imaging showed evacuation of the epidural abscess with a small residual collection. Six days after the procedure, she experienced worsening headaches and MRV showed a nonocclusive thrombus in the superior sagittal sinus, which was treated with anticoagulation therapy. Upon follow-up, the patient showed improvement of the sinusitis, abscess and thrombus. CONCLUSION: This specific case encourages clinicians to be aware of complications, though rare, and to diagnose and treat sinusitis cases quickly. It is also important to be aware of any risk factors for thrombus formation, including an inflammatory and hypercoagulable state. In the patient's case, it was perceived that the CSVT was provoked due to the patient's Covid-19 infection, abscess, and sinus disease.

Presenting symptoms of pediatric brain tumors diagnosed in the emergency department.

OBJECTIVE: The primary objective of this study is to categorize the symptoms associated with brain tumors as diagnosed in the emergency department (ED). The secondary objective is to detail the specific characteristics of these headaches via a subgroup analysis. METHODS: A retrospective chart review was performed among patients younger than 18 years presenting to a large urban tertiary care facility. Electronic medical records were searched and reviewed from 2002 to 2011 for inpatient discharge diagnoses using malignant and benign central nervous system tumor International Classification of Diseases, Ninth Revision codes. RESULTS: The electronic records of ED visits for 87 patients were reviewed. The most frequent signs and symptoms were as follows: headache (66.7%), hydrocephalus (58.6%), nausea/vomiting (49.4%), gait disturbance (42.5%), vision changes (20.7%), seizure (17.2%), behavior/school change (17.2%), cranial nerve deficits (16.1%), altered mental status (16.1%), back/neck pain (16.1%), papilledema (12.6%), facial asymmetry (10.3%), sensory deficits (8.0%), focal motor weakness (6.9%), cranial nerve 6 deficit (6.9%), ptosis (5.7%), macrocephaly (4.6%), asymptomatic (3.4%), and anisocoria (1.1%). The frequencies of location of headache were diffuse (24.1%), frontal (12.1%), occipital (8.6%), and parietal/temporal (6.9%). The severity was described as severe (37.9%) followed by moderate and mild (10.3% and 5.2%, respectively). Most headaches occurred in the morning (13.8%) and night (12.1%), and their quality was predominantly progressively worsening (50.0%) CONCLUSIONS: Brain tumors diagnosed in the ED most commonly present with headache, hydrocephalus, nausea/vomiting, and gate disturbances. The headaches are described as progressively worsening and diffuse most commonly occurring in the morning and night.

Toxic traveler? Latrodectus species envenomation in Michigan with refractory symptoms after antivenin administration.

A 17-year-old male was envenomated on the right forearm by a black widow spider that had presumably traveled in a packaged dishwasher and been shipped from Mexico to Michigan. The patient experienced vomiting and severe pain in his abdomen and chest approximately 30 min after being bitten. He received 6000 units (1 vial) of Latrodectus antivenin intravenously about 7 h after he was envenomated. He did not experience significant improvement in his symptoms after the administration of antivenin and additional antivenin was not given. The patient was hospitalized for 7 days and still was complaining of intermittent episodes of pain in his chest and lower back 3 weeks after envenomation. To avoid prolonged symptomatology and hospitalization, additional Latrodectus antivenin should be given promptly to those individuals whose symptoms are not ameliorated after 1 vial.