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1.
Braz. j. infect. dis ; Braz. j. infect. dis;19(3): 272-277, May-Jun/2015. tab, graf
Artículo en Inglés | LILACS | ID: lil-751877

RESUMEN

Background: Neonatal infection is a serious public health problem. The aim of this study was to assess the influence of the antenatal care on the risk of early-onset neonatal healthcare associated infection in two Brazilian maternities. Methods: Cohort study - Newborns admitted at two public neonatal intensive care units from 2008 to 2009 were included in the study. Data on antenatal and perinatal variables were collected from maternal prenatal cards and medical charts. Newborns were actively surveyed for early-onset neonatal healthcare associated infection, defined as a neonatal infection diagnosed within 48 h after birth. Multiple logistic regression was used to assess variables independently associated with early-onset neonatal healthcare associated infection. Results: 561 neonate-mother pairs were included in the study. Early-onset neonatal health-care associated infection was diagnosed in 283 neonates (51%), an incidence rate of 43.5/1000 live births. Neonates whose mothers had less then six antenatal visits were under risk significantly higher for early-onset neonatal healthcare associated infection (OR = 1.69, 95% CI = 1.11-2.57), after adjusting for birth weight, membranes ruptured for >18 h, maternal complications during delivery, maternal infection at admission, and hospital where patients received care. Conclusions: The risk of neonatal early-onset neonatal healthcare associated infection was significantly associated with insufficient number of antenatal care visits. Further studies assessing the quality of antenatal care and targeting its improvement are warranted. .


Asunto(s)
Femenino , Humanos , Recién Nacido , Masculino , Embarazo , Enfermedades del Recién Nacido/diagnóstico , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Complicaciones Infecciosas del Embarazo/diagnóstico , Atención Prenatal/normas , Brasil , Estudios de Cohortes , Enfermedades Transmisibles , Unidades de Cuidado Intensivo Neonatal , Enfermedades del Recién Nacido/prevención & control , Factores de Riesgo
2.
Braz J Infect Dis ; 19(3): 272-7, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25795268

RESUMEN

BACKGROUND: Neonatal infection is a serious public health problem. The aim of this study was to assess the influence of the antenatal care on the risk of early-onset neonatal healthcare associated infection in two Brazilian maternities. METHODS: Cohort study - Newborns admitted at two public neonatal intensive care units from 2008 to 2009 were included in the study. Data on antenatal and perinatal variables were collected from maternal prenatal cards and medical charts. Newborns were actively surveyed for early-onset neonatal healthcare associated infection, defined as a neonatal infection diagnosed within 48h after birth. Multiple logistic regression was used to assess variables independently associated with early-onset neonatal healthcare associated infection. RESULTS: 561 neonate-mother pairs were included in the study. Early-onset neonatal healthcare associated infection was diagnosed in 283 neonates (51%), an incidence rate of 43.5/1000 live births. Neonates whose mothers had less then six antenatal visits were under risk significantly higher for early-onset neonatal healthcare associated infection (OR=1.69, 95% CI=1.11-2.57), after adjusting for birth weight, membranes ruptured for >18h, maternal complications during delivery, maternal infection at admission, and hospital where patients received care. CONCLUSIONS: The risk of neonatal early-onset neonatal healthcare associated infection was significantly associated with insufficient number of antenatal care visits. Further studies assessing the quality of antenatal care and targeting its improvement are warranted.


Asunto(s)
Enfermedades del Recién Nacido/diagnóstico , Transmisión Vertical de Enfermedad Infecciosa/prevención & control , Complicaciones Infecciosas del Embarazo/diagnóstico , Atención Prenatal/normas , Brasil , Estudios de Cohortes , Enfermedades Transmisibles , Femenino , Humanos , Recién Nacido , Enfermedades del Recién Nacido/prevención & control , Unidades de Cuidado Intensivo Neonatal , Masculino , Embarazo , Factores de Riesgo
3.
J Hosp Infect ; 60(1): 51-5, 2005 May.
Artículo en Inglés | MEDLINE | ID: mdl-15823657

RESUMEN

Ralstonia pickettii and Burkholderia cepacia complex isolates are causes of healthcare-associated infection related to contamination of intravenously administered products. Based on microbiological and epidemiological data and molecular typing by pulsed-field gel electrophoresis, we report the occurrence of two outbreaks of R. pickettii and B. cepacia complex bloodstream infections. The first outbreak occurred from August 1995 to September 1996, and the second outbreak occurred from 28 March to 8 April 1998, affecting adults and neonates, respectively. Infusion of contaminated water for injection was the source of infection.


Asunto(s)
Bacteriemia/etiología , Infecciones por Burkholderia/etiología , Complejo Burkholderia cepacia , Infección Hospitalaria/etiología , Contaminación de Medicamentos , Infecciones por Bacterias Gramnegativas/etiología , Inyecciones/efectos adversos , Ralstonia , Microbiología del Agua , Adulto , Bacteriemia/epidemiología , Brasil/epidemiología , Infecciones por Burkholderia/epidemiología , Complejo Burkholderia cepacia/clasificación , Complejo Burkholderia cepacia/genética , Complejo Burkholderia cepacia/aislamiento & purificación , Infección Hospitalaria/epidemiología , ADN Bacteriano/análisis , ADN Bacteriano/genética , Brotes de Enfermedades/estadística & datos numéricos , Electroforesis en Gel de Campo Pulsado , Resultado Fatal , Femenino , Genotipo , Infecciones por Bacterias Gramnegativas/epidemiología , Humanos , Recién Nacido , Control de Infecciones , Masculino , Epidemiología Molecular , Filogenia , Ralstonia/clasificación , Ralstonia/genética , Ralstonia/aislamiento & purificación , Estaciones del Año
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