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1.
Biomimetics (Basel) ; 9(6)2024 May 30.
Artículo en Inglés | MEDLINE | ID: mdl-38921213

RESUMEN

Mycelium-based composites (MBCs) are biomaterials with scientifically proven potential to improve sustainability in construction. Although mycelium-based products are not entirely new, their use in engineering presents challenges due to the inherent properties of this fungal material. This study investigated professional architects' and interior designers' perceptions of MBCs, focusing on familiarity, aesthetic appeal, and willingness to use. The first phase of the survey explored respondents' views on material-related ecological design principles. In the second phase, respondents evaluated ten small architectural objects crafted from MBCs, focusing on form, detail, and visual appeal. The last phase of the survey measured their interest in using mycelium in their design work. The results revealed that MBCs were relatively unknown among the surveyed professionals; only every second respondent knew this material. Despite this, 90% found MBCs visually appealing after seeing the examples. Interestingly, the natural, unprocessed appearance of the material was assessed as less aesthetically pleasing, with thermal treatment improving its perceived value. Architects were more receptive to using MBCs in their professional projects for customers than for personal use. This observation points to a 'double standard': professional architects are more open to using MBCs in projects not intended for their own use.

2.
Mol Cell Endocrinol ; 590: 112264, 2024 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-38705365

RESUMEN

Reproductive factors play significantly important roles in determining the breast cancer (BC) risk. The impact of pregnancy, abortion, and birth control methods on tumor development remains unclear. It has been found that early full-term pregnancies in young women can lower their lifetime risk of developing the type of cancer in question. However, having a first full-term pregnancy at an older age can increase this risk. The relationship between pregnancy and breast cancer (BC) is, however, much more complicated. Both induced and spontaneous abortions lead to sudden changes in hormonal balance, which could cause different effects on sensitive breast epithelial cells, making abortion a potential risk factor for breast cancer. The influence of hormonal contraception on carcinogenesis is not comprehensively understood, and therefore, more exhaustive analysis of existing data and further investigation is needed. This review explores how the mentioned reproductive factors affect the risk of breast cancer (BC), focusing on the molecular mechanisms that contribute to its complexity. By comprehending this intricate network of relationships, we can develop new strategies for predicting and treating the disease.


Asunto(s)
Aborto Inducido , Neoplasias de la Mama , Humanos , Femenino , Embarazo , Factores de Riesgo , Anticoncepción/métodos
3.
Vaccines (Basel) ; 12(4)2024 Mar 28.
Artículo en Inglés | MEDLINE | ID: mdl-38675748

RESUMEN

Background: The pandemic has proven to be a particular challenge for healthcare workers, not only in the professional but also individual sense. The COVID-19 pandemic negatively influenced their well-being and caused psychological distress. Undoubtedly, direct contact with sick patients, the fight against the pandemic, and observing the epidemiological situation influenced the attitudes of this group towards COVID-19 and vaccinations. The aim of the study was to analyse the level of anxiety among healthcare workers during the COVID-19 pandemic and to assess attitudes towards vaccinations against COVID-19. Methods: The cross-sectional study followed the recommendations of STROBE (Strengthening the Reporting of Observational Studies in Epidemiology). A convenience purposive sampling method was used and the study was led among nurses and doctors employed in healthcare facilities. The study used a survey and the Trait Anxiety Scale SL-C. Results: The study included 385 participants, with an average age of 48.41 ± 6.76 years. The nurses constituted 55% of the study group and the doctors 45%. A total of 70% of healthcare workers had over 10 years of work experience. Over half of the subjects (57%) became infected with COVID-19. A total of 85% of respondents have received vaccination. A total of 71% of respondents believe vaccinations are harmless. Frequently, the participants assessed their level of anxiety as moderate. Conclusions: Almost all surveyed doctors chose to be vaccinated, while the percentage of vaccinated nurses was significantly lower. As a result, it is possible to conclude that the employment position has a significant influence on the decision to get vaccinated against COVID-19. In self-assessment during the COVID-19 pandemic, most healthcare professionals experienced a moderate level of anxiety. Receiving the COVID-19 vaccination reduced the level of anxiety.

4.
Asian Pac J Cancer Prev ; 24(7): 2259-2269, 2023 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-37505755

RESUMEN

OBJECTIVE: The incidence of skin cancer is constantly growing, it is considered a serious problem of public health. Most cases of skin cancer are caused by a combination of non-modifiable genetic, and modifiable environmental risk factors. The study objective was to analyse the correlation between pigmentation traits, excessive sunlight exposure, solarium use and the risk of melanoma development. METHODS: The study included 480 patients diagnosed with melanoma and 400 within the control group. Subjects diagnosed with the melanoma confirmed by histopathology were invited to take part in the study. The research was based on a clinical, direct, individual, structured, in-depth and focused interview. RESULTS: The mean age of the study subjects was 44.3 ± 7.86, while in the control group 59.5 (7.93) Most frequently, melanoma was located on the upper extremities (64%). A family history of neoplastic diseases was found in 55% of the patients. The assessment of sunburns showed that only 15%  of the respondents never experienced sunburn, 49% of the study subjects never used solarium. Among patients with multiple sunburns, the risk of developing skin cancer was 1.27 (AOR = 1,27; 95% CI, 1.07-1.55) compared with non-sunburns subjects. CONCLUSIONS: Risky behaviours including excessive exposure to UV radiation, both natural and artificial, are of special significance in women with fair complexion and fair hair. Indoor tanning is a probable factor of increased skin cancer incidence in younger women, as compared to men.


Asunto(s)
Melanoma , Neoplasias Cutáneas , Quemadura Solar , Masculino , Humanos , Femenino , Polonia/epidemiología , Luz Solar/efectos adversos , Melanoma/epidemiología , Melanoma/etiología , Neoplasias Cutáneas/epidemiología , Neoplasias Cutáneas/etiología , Quemadura Solar/complicaciones , Quemadura Solar/epidemiología , Factores de Riesgo
5.
Biomedicines ; 11(4)2023 Apr 10.
Artículo en Inglés | MEDLINE | ID: mdl-37189761

RESUMEN

Spinal cord injuries (SCIs) are associated with a high risk of thromboembolic complications (VTE), despite the use of antithrombotic prophylaxis in the form of low-molecular-weight heparin (LMWH). The occurrence of VTE requires, as in other diseases, full-dose antithrombotic treatment. Herein, we describe seven cases of soft tissue hemorrhagic complications in the form of spontaneous intramuscular hematomas (SMHs) in patients after SCI undergoing rehabilitation. Four patients received anticoagulant therapy due to previously diagnosed deep vein thrombosis (DVT), and three patients received anticoagulant prophylaxis. None of the patients had a significant injury immediately before the hematoma appeared, and the only symptom was a sudden swelling of the limb without accompanying pain. The hematomas in all patients were treated conservatively. In three patients, significant decreases in hemoglobin were observed; in one patient, a blood transfusion was required for this reason. In all patients treated via anticoagulation, the anticoagulation treatment was modified at the time of diagnosis of the hematoma; in three patients, oral anticoagulants were changed to LMWH in a therapeutic dose, while in one patient, anticoagulant treatment was completely discontinued. Conclusions: Intramuscular hematomas are rare complications after SCI. Each sudden swelling of a limb requires ultrasound-based diagnostics. At the time of diagnosis of a hematoma, the level of hemoglobin and the size of the hematoma should be monitored. The treatment or anticoagulation prophylaxis should be modified if necessary.

6.
Cancers (Basel) ; 15(8)2023 Apr 14.
Artículo en Inglés | MEDLINE | ID: mdl-37190225

RESUMEN

PURPOSE: Low back pain presents a serious challenge for numerous medical specialties. The purpose of this study was to assess disability due to low back pain in patients operated on due to colorectal cancer depending on the type of surgery performed. METHODS: This prospective observational study was carried out in the period of July 2019 through March 2020. Included in the study were patients with colorectal cancer for scheduled surgeries including anterior resection of rectum (AR), laparoscopic anterior resection of rectum (LAR), Hartmann's procedure (HART), or abdominoperineal resection of rectum (APR). The Oswestry Low Back Pain Disability Questionnaire was used as the research tool. The study patients were surveyed at three time points: before surgery, six months after surgery, and one year after surgery. RESULTS: The analysis of study results revealed that an increase in the degree of disability and functioning impairment occurred in all groups between time points I and II, with the differences being statistically significant (p < 0.05). The inter-group comparative analysis of the total Oswestry questionnaire scores revealed statistically significant differences, with the impairment of function being most severe within the APR group and least severe within the LAR group. CONCLUSION: The study results showed that low back pain contributes to impaired functioning of patients operated on due to colorectal cancer regardless of the type of procedure performed. A reduction in the degree of disability due to low back pain was observed one year after the procedure in patients having undergone LAR.

7.
Artículo en Inglés | MEDLINE | ID: mdl-36673734

RESUMEN

BACKGROUND: Today, cardiovascular diseases cause 47% of all deaths among the European population, which is 4 million cases every year. In Ukraine, CAD accounts for 65% of the mortality rate from circulatory system diseases of the able-bodied population and is the main cause of disability. The aim of this study is to develop a medical expert system based on fuzzy sets for assessing the degree of coronary artery lesions in patients with coronary artery disease. METHODS: The method of using fuzzy sets for the implementation of an information expert system for solving the problems of medical diagnostics, in particular, when assessing the degree of anatomical lesion of the coronary arteries in patients with various forms of coronary artery disease, has been developed. RESULTS: The paper analyses the main areas of application of mathematical methods in medical diagnostics, and formulates the principles of diagnostics, based on fuzzy logic. The developed models and algorithms of medical diagnostics are based on the ideas and principles of artificial intelligence and knowledge engineering, the theory of experiment planning, the theory of fuzzy sets and linguistic variables. The expert system is tested on real data. Through research and comparison of the results of experts and the created medical expert system, the reliability of supporting the correct decision making of the medical expert system based on fuzzy sets for assessing the degree of anatomical lesion of the coronary arteries in patients with various forms of coronary artery disease with the assessment of experts was 95%, which shows the high efficiency of decision making. CONCLUSIONS: The practical value of the work lies in the possibility of using the automated expert system for the solution of the problems of medical diagnosis based on fuzzy logic for assessing the degree of anatomical lesion of the coronary arteries in patients with various forms of coronary artery disease. The proposed concept must be further validated for inter-rater consistency and reliability. Thus, it is promising to create expert medical systems based on fuzzy sets for assessing the degree of disease pathology.


Asunto(s)
Enfermedades Cardiovasculares , Enfermedad de la Arteria Coronaria , Humanos , Sistemas Especialistas , Inteligencia Artificial , Enfermedad de la Arteria Coronaria/diagnóstico , Reproducibilidad de los Resultados , Lógica Difusa , Algoritmos
8.
Artículo en Inglés | MEDLINE | ID: mdl-36361404

RESUMEN

The Act on the Pharmacist Profession, adopted on 10 December 2020, is a breakthrough for the entire community of pharmacists in Poland. Due to the scope of the changes introduced in the Act, the question is whether pharmacists in Poland are suitably prepared for pharmaceutical care and clinical pharmacy services. The main aim of the study is to assess the readiness of hospital pharmacists to introduce changes in the way the profession functions. The result of the study is the presentation of the concept of a new model of pharmacist functioning in healthcare entities and the indication of actions necessary to carry out such a change. The questionnaire was addressed to all hospital pharmacists in Poland. Two hundred and seventy-seven hospital pharmacists were included in the research. The analysis of the data revealed that almost all (96.1%) respondents indicated the need to introduce changes to the model of functioning of pharmacists in medical entities. Two-thirds of pharmacists declared readiness to start work to introduce changes. Hospital pharmacists recognize the importance of clinical pharmacy in their current practice; however, the biggest barrier is the lack of financing, an insufficient number of staff, a lack of knowledge and skills, and a lack of tools to use the service.


Asunto(s)
Servicios Comunitarios de Farmacia , Servicio de Farmacia en Hospital , Humanos , Farmacéuticos , Polonia , Encuestas y Cuestionarios , Hospitales , Rol Profesional , Actitud del Personal de Salud
9.
Children (Basel) ; 9(10)2022 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-36291498

RESUMEN

(1) Background: The onset and duration of the child's illness is a difficult test for the entire family. The stress, in which the family lives from this moment, influences the relationships within it, as well as external relations with the environment. The child's cancer fundamentally changes the way the family functions, the quality of interactions within the family, and life plans. (2) Patients and Approach: A population survey was run between 2015 and 2020. A cross-sectional study was conducted involving 800 family caregivers of children with cancer during active treatment. The aim of the study was to assess changes in the family functioning in the opinion of parents of a child with cancer. (3) Results: Parents experience chronic anxiety (67%), nervousness (60%), and worry (64%). For 50% of parents, the illness of their child entirely changed their plans. As many as 75% of parents feel guilty for exposing their child to carcinogens. According to the parents, the child's illness is a psychological (89%), somatic (49%) and financial (77%) burden for them. Only 7% of children cause behavioural problems and 16% have trouble learning due to their sibling's illness. (4) Conclusions: Cancer is a great difficulty for all members of a family system. The disease disturbs the balance within the family and relations in the family, as well as more distant psychological, social, and material consequences.

10.
Asian Pac J Cancer Prev ; 23(10): 3299-3307, 2022 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-36308352

RESUMEN

OBJECTIVE: Lung cancer is one of the most common and deadly malignant neoplasms. Currently, it is one of the main causes of cancer deaths worldwide. The study aimed to identify and evaluate patient characteristics, demographic and lifestyle factors that are associated with lung cancer at diagnosis. METHODS: The study included 400 patients diagnosed with lung cancer and 400 within the control group. The research was based on a clinical, direct, individual, structured, in-depth and focused interview. Assessment of activity and BMI was used according to WHO recommendations, as well as the expert system. RESULTS: The mean age of the patients was 74.53 ± 7.86 years, while in the control group 59.5 (7.93). There was a strong positive relationship between the incidence of tuberculosis and chronic obstructive pulmonary disease and the risk of lung cancer (p <0.001). The risk of lung cancer was significant in the case of smoking 20 or more than 20 cigarettes a day and smoking for more than 20 years (p = 0.01). CONCLUSIONS: Active and passive smoking, are a leading risk factor for lung cancer, which shows that understanding of the long-term and fatal effects of smoking is still very low in society.  No significant correlation has been found between lifestyle and risk of lung cancer. However, there was a strong positive correlation between tuberculosis and chronic obstructive pulmonary disease and the risk of lung cancer. Occupation is a predisposing factor for lung cancer occurrence.


Asunto(s)
Neoplasias Pulmonares , Enfermedad Pulmonar Obstructiva Crónica , Tuberculosis , Humanos , Anciano , Anciano de 80 o más Años , Fumar/efectos adversos , Fumar/epidemiología , Estudios de Casos y Controles , Polonia/epidemiología , Factores de Riesgo , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/epidemiología , Neoplasias Pulmonares/etiología , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Enfermedad Pulmonar Obstructiva Crónica/epidemiología
11.
Sci Rep ; 12(1): 15281, 2022 09 10.
Artículo en Inglés | MEDLINE | ID: mdl-36088380

RESUMEN

Graphical user interfaces are designed so that the most important elements are usually located in the central part of the screen, where they catch the user's attention. However, there are situations where it is necessary to attract the user's attention to make him/her notice, e.g., a critical alert, which is customarily displayed in the peripheral area so as not to interact with the main content. Therefore, our focus is to deliver an increased visibility of content in the peripheral area of the display in a non-intrusive way. Thus, the main purpose of this work is to analyze the visibility of the stimulus (in the form of colored discs), displayed in the peripheral area of a screen, which distracts users from the central part of the interface. The habituation and sensitization effects were considered to study which parameters catch and hold the user's attention, despite the length of their interaction with the system. The experiments performed indicated how the parameters should be set to reduce the habituation effect without the need to use content with the highest visual intensity. The results showed that a high visual intensity is not necessarily needed for the best impact. A medium contrast level, a horizontal or vertical display localization, and a flashing frequency of 2 Hz are sufficient to obtain the best visibility in the peripheral area. In the case of critical alerts and the need for short-term intensive stimuli, it is worth highlighting these with high contrast. This configuration should be the most effective if it is not a continuous operation. However, they can cause unnecessary irritation or even cognitive load for more extended usage.


Asunto(s)
Habituación Psicofisiológica , Femenino , Humanos , Masculino
12.
Sensors (Basel) ; 22(9)2022 May 06.
Artículo en Inglés | MEDLINE | ID: mdl-35591226

RESUMEN

The essential factor that enables medical patient monitoring is the vital signs monitor, whereas the key in communication with the monitor is the user interface. The way the data display on the monitors is standard, and it is often not changed; however, vital signs monitors are now configurable. Not all the data have to be displayed concurrently; not all data are necessary at a given moment. There arises a question: is the standard monitor configuration sufficient, or can it lead to mistakes related to delays in perceiving parameter changes? Some researchers argue that mistakes in life-saving activities is not mainly due to medical mistakes but due to poorly designed patient life monitor interfaces, among other reasons. In addition, it should be emphasized that the activity that saves the patient's life is accompanied by stress, which is often caused by the chaos occurring in the hospital emergency department. This raises the following question: is the standard user interface, which they are used to, still effective under stress conditions? Therefore, our primary consideration is the measure of reaction speed of medical staff, which means the perception of the changes of vital signs on the patient's monitor, for stress and stressless situations. The paper attempts to test the thesis of the importance of the medical interface and its relation to medical mistakes, extending it with knowledge about the difference in speed of making decisions by the medical staff with regard to the stress stimulus.


Asunto(s)
Errores Médicos , Signos Vitales , Humanos , Monitoreo Fisiológico
13.
Diagnostics (Basel) ; 12(4)2022 Apr 07.
Artículo en Inglés | MEDLINE | ID: mdl-35453970

RESUMEN

Intra-vesical instillations with bacillus Calmette-Guerin (BCG) are the established adjuvant therapy for superficial bladder cancer. Although generally safe and well tolerated, they may cause a range of different, local, and systemic complications. We present a patient treated with BCG instillations for three years, who was admitted to our hospital due to fever, hemoptysis, pleuritic chest pain and progressive dyspnea. Chest computed tomography (CT) showed massive bilateral ground glass opacities, partly consolidated, localized in the middle and lower parts of the lungs, bronchial walls thickening, and bilateral hilar lymphadenopathy. PCR tests for SARS-CoV-2 as well as sputum, blood, and urine for general bacteriology-were negative. Initial empiric antibiotic therapy was ineffective and respiratory failure progressed. After a few weeks, a culture of M. tuberculosis complex was obtained from the patient's specimens; the cultured strain was identified as Mycobacterium bovis BCG. Anti-tuberculous treatment with rifampin (RMP), isoniazid (INH) and ethambutol (EMB) was implemented together with systemic corticosteroids, resulting in the quick improvement of the patient's clinical condition. Due to hepatotoxicity and finally reported resistance of the BCG strain to INH, levofloxacin was used instead of INH with good tolerance. Follow-up CT scans showed partial resolution of the pulmonary infiltrates. BCG infection in the lungs must be taken into consideration in every patient treated with intra-vesical BCG instillations and symptoms of protracted infection.

14.
Medicina (Kaunas) ; 58(2)2022 Jan 27.
Artículo en Inglés | MEDLINE | ID: mdl-35208519

RESUMEN

Background and objectives: Current studies show an important role of affective temperament in sport performance. The aim of this study was to assess the feasibility of the use of the TEMPS-A scale, by using it to examine five dimensions of affective temperament in three groups of athletes. We hypothesized that temperament may be a predisposing factor to the level of commitment and type of training. Materials and methods: The study group (N:71, 33 female) consisted of professional canoeists (N:25, aged 18-30), sports pilots (N:21, aged 19-57) and non-professionals regularly performing aerobic exercises (N:25, aged 23-33). The Affective Temperament of Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A) was used to evaluate affective temperament dimensions. Statistical analysis was performed using non-parametric tests. Results: The TEMPS_A scale shows good internal consistency; a hyperthymic temperament was associated with different factors compared to other temperament traits. The most prevalent trait in the study group was hyperthymic temperament. The study group scored higher on hyperthymic and lower on depressive and anxious temperaments when compared with the general population. Canoeists scored higher on cyclothymic temperament compared with non-professional athletes and on cyclothymic and irritable dimensions in comparison with pilots. Pilots obtained significantly lower scores on irritable and anxious temperaments than non-professional athletes. Females scored higher on both hyperthymic and irritable dimensions. No significant differences were found in respect of depressive, cyclothymic and anxious traits. Age was negatively correlated with cyclothymic and irritable temperament scores. Conclusions: TEMPS-A scale is a useful tool for assessing affective temperament in athletes. The results suggest that affective temperament may be a factor influencing physical activity engagement. Different types of activities may be connected with different temperament dimensions. Younger athletes present a higher tendency to mood lability and sensitivity to environmental factors. However, further research is needed, involving larger numbers of subjects.


Asunto(s)
Comparación Transcultural , Temperamento , Adolescente , Adulto , Atletas , Estudios de Factibilidad , Femenino , Humanos , Persona de Mediana Edad , Inventario de Personalidad , Psicometría , Reproducibilidad de los Resultados , Encuestas y Cuestionarios , Adulto Joven
15.
Children (Basel) ; 9(2)2022 Jan 23.
Artículo en Inglés | MEDLINE | ID: mdl-35204865

RESUMEN

BACKGROUND: Parents experience many healthcare needs when caring for their sick children. Research shows that parents of oncological children have a high level of unmet needs, including psychosocial, emotional, physical, informational, financial, educational, and spiritual needs. To date, little quantitative research has been carried out on the specific needs of parents of children with cancer, which creates uncertainty about what areas should be addressed in care. This study investigated the prevalence of unmet needs among parents of children with cancer. METHODS: A population survey was conducted between 2015 and 2020. Caregivers of children diagnosed with cancer were invited to participate in the study to assess their problems and needs. RESULTS: The analysis found that 97% of the participants experienced some level of need for one or more items, and 73% of the respondents reported a moderate or high need for one or more items. In the field of medical information, 70% of respondents had moderate or high needs, 55% of parents reported a moderate or high level of need for help in the psychological or emotional field, and 30% in the financial domain. The prevalence of moderate or high need in the remaining domains ranged from 10% to 15%. CONCLUSIONS: Parents of children with cancer experience a high level of needs, especially psychological, emotional, and information. These data suggest that the existing healthcare system does not meet the needs of parents of sick children. The results show the need to investigate the mechanisms by which healthcare providers can use the healthcare system to identify and meet needs.

16.
Sensors (Basel) ; 22(2)2022 Jan 11.
Artículo en Inglés | MEDLINE | ID: mdl-35062508

RESUMEN

When reading interesting content or searching for information on a website, the appearance of a pop-up advertisement in the middle of the screen is perceived as irritating by a recipient. Interrupted cognitive processes are considered unwanted by the user but desired by advertising providers. Diverting visual attention away from the main content is intended to focus the user on the appeared disruptive content. Is the attempt to reach the user by any means justified? In this study, we examined the impact of pop-up emotional content on user reactions. For this purpose, a cognitive experiment was designed where a text-reading task was interrupted by two types of affective pictures: positive and negative ones. To measure the changes in user reactions, an eye-tracker (for analysis of eye movements and changes in gaze points) and an iMotion Platform (for analysis of face muscles' movements) were used. The results confirm the impact of the type of emotional content on users' reactions during cognitive process interruptions and indicate that the negative impact of cognitive process interruptions on the user can be reduced. The negative content evoked lower cognitive load, narrower visual attention, and lower irritation compared to positive content. These results offer insight on how to provide more efficient Internet advertising.


Asunto(s)
Emociones , Movimientos Oculares , Publicidad , Lectura
17.
Cancer Control ; 29: 10732748211056692, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35000418

RESUMEN

BACKGROUND: Colorectal cancer defined as cancer of the colon or rectum, is the third most frequently diagnosed cancer in men and the second in women, and, according to the World Health Organization database GLOBOCAN, it accounts for nearly 1.4 million new cases annually worldwide. The occurrence of colorectal cancer is associated with nonmodifiable risk factors, including age and hereditary factors, as well as with modifiable environmental and lifestyle factors. METHODS: The study included 800 patients, 400 diagnosed with colorectal cancer and 400 within the control group, who gave their written informed consent to participate in the study. Patients with cancer other than colorectal cancer were randomly selected for control group I, and patients with no cancer diagnosis were selected for control group II. The method used was a case-control study - an observational and analytical study with a control group, conducted among patients of the Clinical Oncology Centre and the Provincial Hospital in the years 2019-2020. The study comparing the exposure was carried out in a group of people who developed the endpoint, that is colorectal cancer, with the exposure in a well-matched group of controls who did not reach the endpoint. Assessment of activity and BMI was used according to WHO recommendations, as well as the expert system. The data were tested for the distribution and the homogeneity of variance was validated before applying the parameter tests. Comparison of quantitative variables between groups was performed using ANOVA. RESULTS: The mean age of the patients was 64.53 ± 8.86 years, of the control group I - 59.64 ± 9.33 and the control group II - 57.5 (7.83). There was a strong positive association between the incidence of ulcerative colitis and the risk of colorectal cancer (P < .01). Among obese subjects, the risk of developing colorectal cancer was 1.27 (95% CI, 1.06-1.53) compared with nonobese subjects. A strong positive relationship was found between low physical activity converted to metabolic equivalent of MET effort per week and the risk of colorectal cancer (P < .001). The relative risk for current smokers was 2.17 (95% CI 1.79-2.66). There was an association between higher fat consumption and higher red meat consumption and the risk of developing colorectal cancer (P < .01). CONCLUSIONS: Obesity, low physical activity, active and passive smoking and high salt and red meat consumption have been associated with an increased risk of colorectal cancer. These findings provide further evidence of the importance of maintaining a healthy lifestyle.


Asunto(s)
Neoplasias Colorrectales/diagnóstico , Neoplasias Colorrectales/etiología , Detección Precoz del Cáncer/estadística & datos numéricos , Anciano , Estudios de Casos y Controles , Colitis Ulcerosa/complicaciones , Colitis Ulcerosa/epidemiología , Neoplasias Colorrectales/epidemiología , Dieta/efectos adversos , Dieta/estadística & datos numéricos , Ejercicio Físico/estadística & datos numéricos , Femenino , Humanos , Incidencia , Estilo de Vida , Masculino , Persona de Mediana Edad , Obesidad/complicaciones , Obesidad/epidemiología , Factores de Riesgo , Fumar/efectos adversos , Fumar/epidemiología
18.
Sensors (Basel) ; 21(24)2021 Dec 20.
Artículo en Inglés | MEDLINE | ID: mdl-34960596

RESUMEN

Interactive environments create endless possibilities for the design of websites, games, online platforms, and mobile applications. Their visual aspects and functional characteristics influence the user experience. Depending on the project, the purpose of the environment can be oriented toward marketing targets, user experience, or accessibility. Often, these conflicting aspects should be integrated within a single project, and a search for trade-offs is needed. One of these conflicts involves a disparity in user behavior concerning declared preferences and real observed activity in terms of visual attention. Taking into account accessibility guidelines (WCAG) further complicates the problem. In our study, we focused on the analysis of color combinations and their contrast in terms of user-friendliness; visual intensity, which is important for attracting user attention; and recommendations from the Web Accessibility Guidelines (WCAG). We took up the challenge to reduce the disparity between user preferences and WCAG contrast, on one hand, and user natural behavior registered with an eye-tracker, on the other. However, we left the choice of what is more important-human conscious reaction or objective user behavior results-to the designer. The former corresponds to user-friendliness, while the latter, visual intensity, is consistent with marketing expectations. The results show that the ranking of visual objects characterized by different levels of contrast differs when considering the perspectives of user experience, commercial goals, and objective recording. We also propose an interactive tool with the possibility of assigning weights to each criterion to generate a ranking of objects.

19.
Children (Basel) ; 8(12)2021 Dec 10.
Artículo en Inglés | MEDLINE | ID: mdl-34943367

RESUMEN

BACKGROUND: Cancer diseases in children and adolescents are considered to be one of the most serious health problems in the world. It is estimated that about 151,435 cases are diagnosed in children annually. Children with cancer experience many comorbid symptoms related to diagnosis and treatment that can profoundly affect their lives. They experience physical and emotional suffering, which affects their well-being and physical fitness, influencing the prognosis and deteriorating their physical, mental and social functioning. Given the limited data, an attempt was made to assess the problems of the biopsychosocial sphere of need and stressors among children and adolescents treated for cancer. Accurate symptom assessment is essential to ensure high-quality care and effective treatment. PATIENTS AND METHODS: The qualitative study was conducted in pediatric oncology of hospitals in Poland. Children diagnosed with cancer were invited to participate in the study to assess their problems, stressors and needs. RESULTS: The study included 520 people, where female sex constituted 48% and male 52%. The mean age of the children is 13.2 SD = 2.5. Negative experiences related to the disease are experienced by 82% of children. Among the surveyed children, the most experienced were anxiety (61%). The conducted research shows that as many as 69% of all respondents experienced states that indicate severe depression. The most common somatic problems reported by children were pain (58%). The most dominant areas of life that had a negative impact was body image (85%). CONCLUSIONS: Children and adolescents diagnosed with neoplastic disease experience many problems and stressors in every sphere of life, which undoubtedly affects a high level of unmet needs. The main category of needs concerning the challenges faced by children with cancer was psychological and care problems. In the youth group, the needs were mainly related to education and social support.

20.
Artículo en Inglés | MEDLINE | ID: mdl-34886419

RESUMEN

The experience of hospitalization of a newborn in the Neonatal Intensive Care Unit (NICU) may become distressing both for the baby and parent. The study aimed to assess the degree of parental stress and coping strategies in parents giving KMC to their babies hospitalized in NICU compared to the control group parents not giving KMC. The prospective observational study enrolled a cohort of 337 parents of premature babies hospitalized in NICU in 2016 in Eastern Poland. The Parental Stressor Scale: Neonatal Intensive Care Unit, Coping Inventory for Stressful Situations were used. The level of stress in parents giving KMC was defined as low or moderate. Analysis confirmed its greater presence in the group of parents initiating KMC late (2-3 weeks) compared to those starting this initiative in week 1 of a child's life. An additional predictor of a higher level of stress in parents initiating KMC "late" was the hospital environment of a premature baby. Task oriented coping was the most common coping strategy in the study group. KMC and direct skin-to-skin contact of the parent with the baby was associated with a higher level of parental stress only initially and decreased with time and KMC frequency.


Asunto(s)
Método Madre-Canguro , Adaptación Psicológica , Niño , Hospitalización , Humanos , Lactante , Recién Nacido , Unidades de Cuidado Intensivo Neonatal , Percepción
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