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1.
Front Aging Neurosci ; 16: 1412542, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39170900

RESUMEN

Background: The association between lung function and motoric cognitive risk syndrome (MCR) is unclear. We aimed to explore the association of peak expiratory flow (PEF) with MCR using cross-sectional and longitudinal analyses. Methods: Within the CHARLS, 5095 participants were included in the cross-sectional analysis, and 4340 MCR-free participants were included in the longitudinal analysis. The PEF was assessed with a lung peak flow meter. MCR was characterized by cognitive complaints and a slow walking speed with normal mobility and without dementia. Logistic regression, Cox regression, and Laplace regression models were employed for data analysis. Results: In this cross-sectional study, logistic regression analyses revealed that continuous PEF was associated with MCR (odds ratio [OR], 0.998; 95% confidence interval [CI], 0.998, 0.999), and the ORs (95% CIs) of MCR prevalence were 0.857 (0.693, 1.061) for the middle tertile and 0.665 (0.524, 0.845) for the highest tertile compared to the lowest tertile. In a longitudinal cohort study, continuous PEF was dose-dependently associated with the risk of MCR. Compared with those in the lowest tertile of PEF, the hazard ratios (95% CIs) of incident MCR were 0.827 (0.661, 1,036) for the middle tertile and 0.576 (0.432, 0.767) for the highest tertile. Furthermore, compared with the lowest tertile, the highest tertile was associated with a delayed onset time of MCR of 0.484 (95% CI: 0.151, 0.817) years. Conclusion: A higher PEF was related to a lower prevalence of MCR and a lower risk for MCR, and a higher PEF also prolonged the onset time of MCR.

2.
Phys Chem Chem Phys ; 26(16): 12681-12697, 2024 Apr 24.
Artículo en Inglés | MEDLINE | ID: mdl-38600841

RESUMEN

The intrinsic ferromagnetism of two-dimensional transition metal carbide Co2C is remarkable. However, its practical application in spintronic devices is encumbered by a low Curie temperature (TC). To surmount this constraint, double transition-metal carbide CoMC (M = Ti, V, Cr, Mn, Fe, Ni) monolayers are constructed with the aim of improving the magnetic properties and Curie temperature of Co2C. The magnetic properties of CoMC monolayers are comprehensively investigated by first-principles calculations and the effects of hole doping and biaxial strain on the magnetic properties of CoMC (M = V, Cr, Mn) monolayers are also studied. The ground states of CoTiC, CoMnC and CoNiC monolayers all favor ferromagnetic ordering, whereas the CoVC and CoCrC monolayers favor antiferromagnetic ordering and the CoFeC monolayer is non-magnetic. Excitedly, the CoMnC monolayer displays a high total magnetic moment of 4.024µB and a TC of 1366 K. Moreover, the control of hole doping can effectively improve the TC of CoVC, CoCrC, and CoMnC monolayers to 680, 1317, 3044 K, respectively. Finally, applying the in-plain biaxial strain, the CoVC monolayer can be transformed into a ferromagnetic semiconductor under a tensile strain of 6%. The TC values of CoVC, CoCrC, and CoMnC monolayers are tuned by biaxial strain to 440, 1334 and 2390 K, respectively. Their TC above room temperature demonstrates that these monolayers have potential applications in spintronic devices. These theoretical investigations provide valuable insights into guiding experimental synthesis endeavors.

3.
Phys Chem Chem Phys ; 26(1): 267-277, 2023 Dec 21.
Artículo en Inglés | MEDLINE | ID: mdl-38059372

RESUMEN

Two-dimensional ferromagnets with a long-range ferromagnetic ordering at finite temperature present a bright prospect for their potential applications in nanoscale spintronic devices. The tuning of their intrinsic ferromagnetism and Curie temperature is essential for the development of next-generation data storage and spintronic devices. In this work, the electronic structures, ferromagnetism and Curie temperature of two-dimensional MnS2 monolayer are controlled by charge doping and electric field using first principles calculations. The results show that the dynamic and thermal stability of monolayer MnS2 for all of the cases can be still maintained. Moreover, there is no existence of phase transition and all MnS2 monolayers at any charge doping concentrations and electric field intensities favor ferromagnetic coupling. For the manipulation of electron doping, the calculated total magnetic moment Mtot of the MnS2 monolayer exhibits an increase from 3.112 to 3.491µB per unit cell. Further analysis indicates that a transition from half-metal to metal occurs by introducing the charge doping and vertical electric field, and the Mn 3d electronic states are the major determinants of ferromagnetism. Additionally, the charge doping enables the magnetic anisotropy energy to transform from an in-plane easy axis to the magnetization direction out of the plane. The Curie temperature Tc of the MnS2 monolayer can be moderately enhanced above room temperature by hole doping and application of a vertical electric field. Remarkably, Tc reaches its peak at 767 K at a hole doping concentration of -0.8e. This work enriches the microscopic understanding of the tuning mechanism of ferromagnetism and supplies a sound theoretical basis for subsequent experimental studies.

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