RESUMEN
The non-Hodgkin lymphomas (NHL) represent an heterogeneous group of malignancies of lymphoreticular histogenesis. In most cases, they initially arise within lymph nodes but so-called extranodal lymphomas are also found. The NHL has low incidence in the oral cavity. It may involve bone and/or soft tissues as a primary or secondary manifestation. We present a review of the literature and four clinical cases of intraoral NHL. The first couple of cases are primary forms, the third one is associated to HIV infection and the last one is an oral presentation as a component of more widely disseminated disease.
Asunto(s)
Linfoma no Hodgkin/patología , Neoplasias de la Boca/patología , Adulto , Anciano , Femenino , Humanos , Linfoma no Hodgkin/terapia , Masculino , Persona de Mediana Edad , Neoplasias de la Boca/terapia , Estadificación de NeoplasiasRESUMEN
Los linfomas no-Hodgkin (LNH) incluyen un grupo heterogéneo de malignidades de histogénesis linforreticular. La mayoría de casos inician en los nódulos linfáticos, aunque existe también la forma extraganglionar. En la cavidad oral el LNH tiene baja incidencia. Puede afectar a los maxilares y/o tejidos blandos como manifestación primaria o secundaria de la enfermedad. Presentamos una revisión de la literatura y cuatro casos clínicos de LNH intraoral, con el propósito de describir sus características clínicas e histológicas. Los dos primeros casos son linfomas intraorales primarios, un tercero asociado a infección VIH y por último una manifestación oral como parte de la diseminación de la enfermedad (AU)
The non-Hodgkin lymphomas (NHL) represent an heterogeneous group of malignancies of lymphoreticular histogenesis. In most cases, they initially arise within lymph nodes but so-called extranodal lymphomas are also found. The NHL has low incidence in the oral cavity. It may involve bone and/or soft tissues as a primary or secondary manifestation. We present a review of the literature and four clinical cases of intraoral NHL. The first couple of cases are primary forms, the third one is associated to HIV infection and the last one is an oral presentation as a component of more widely disseminated disease (AU)
Asunto(s)
Persona de Mediana Edad , Adulto , Anciano , Masculino , Femenino , Humanos , Linfoma no Hodgkin/patología , Neoplasias de la Boca/patología , Estadificación de Neoplasias , Linfoma no Hodgkin/terapia , Neoplasias de la Boca/terapiaRESUMEN
OBJECTIVE: The aim of this investigation was to determine if an association exists between hepatitis C virus and oral lichen planus. STUDY DESIGN: Three groups of subjects were selected: 505 patients with hepatitis C virus infection (group 1), 100 patients with oral lichen planus (group 2), and a randomly selected control group (age- and gender-matched) of 100 healthy subjects (group 3). The prevalence of oral lichen planus was determined in groups 1 and 3, and the prevalence of hepatitis C virus infection was established in groups 2 and 3. RESULTS: The prevalence of oral lichen planus was 3.36% (n = 17) in group 1 and 1% (n = 1) in the control group; the prevalence of hepatitis C virus infection was 23% (n = 23) in group 2, and 5% (n = 5) in the control group. No significant differences were observed in the incidence of oral lichen planus in group 1 between those patients who received interferon and those who did not. The 17 patients in group 1 who manifested oral lichen planus and hepatitis C virus infection simultaneously exhibited a marked tendency to have only reticular lesions (70.6%), with involvement of the buccal mucosa in 88.2% of these patients, the tongue in 29.4%, and the gingiva in 11.8%. Analyzing a randomized subgroup of 143 patients from group 1 (subgroup 1) that was matched by age and gender with groups 2 and 3, we found that the incidence of oral lichen planus in patients with hepatitis C virus infection (subgroup 1) was greater than in the control group (5.59% vs 1%), though this was not statistically significant (chi2 = 0.119; p = 0.06). In contrast, group 2 exhibited a statistically significant higher incidence of hepatitis C virus infection (23%) than the controls (5%; chi2 = 0.259, p = 0.0002). CONCLUSIONS: The prevalence of hepatitis C virus infection in patients with oral lichen planus was greater than in the control series. In our opinion this observation warrants the investigation of potential concomitant hepatitis C virus infection in patients with oral lichen planus.
Asunto(s)
Hepatitis C/complicaciones , Liquen Plano Oral/complicaciones , Candidiasis Bucal/complicaciones , Estudios de Casos y Controles , Distribución de Chi-Cuadrado , Femenino , Enfermedades de las Encías/complicaciones , Enfermedades de las Encías/patología , Hepatitis C/terapia , Humanos , Incidencia , Interferones/uso terapéutico , Leucoplasia Bucal/complicaciones , Liquen Plano Oral/patología , Masculino , Persona de Mediana Edad , Mucosa Bucal/patología , Prevalencia , Estomatitis Aftosa/complicaciones , Enfermedades de la Lengua/complicaciones , Enfermedades de la Lengua/patologíaRESUMEN
A study was made of the dental findings in 100 patients with liver cirrhosis (LC) by examining the number of carious, missing and filled teeth. A significantly greater number of carious and missing teeth were observed in the patients with cirrhosis than in a control group of 50 healthy individuals. In the LC group, caries were found to affect more teeth in those patients with alcohol-induced LC than in those with liver disease of other causes. Finally, no relationship was observed between the number of carious, missing or filled teeth and certain determinations including serum glutamate pyruvate transaminase (SGPT), serum glutamate oxalacetate transaminase (SGOT), alkaline phosphate, platelet number, hepatitis B and C positivity markers, or antinuclear (ANA), antimitochondrial (AMA) or anti-smooth muscle autoantibodies (ASm).
