RESUMEN
OBJECTIVE: The present study sought to analyze the influence of Levetiracetam (LEV) in cognitive performance by identifying the changes produced by LEV in reaction time, in neuropsychological assessment of attention and memory and in absolute theta power in frontal activity. METHODS: Twelve healthy subjects (5 men and 7 women; mean age, 30.08 years, standard deviation, 4.71) were recruited for this study. The neuropsychological tests: Trail Making Test (A and B), Digit Span (direct and indirect numerical orders/working memory); Stroop test (inhibitory control of attention); Tower of London (planning and decision-making) and a quantitative electroencephalography were applied in 2 different days after and before the participants ingested the capsule of placebo or 500 mg LEV. RESULTS: A two-way-ANOVA was implemented to observe the interaction between conditions (placebo or LEV 500 mg) and moments (pre- and post-ingestion of LEV or placebo). The data were analyzed by the SPSS statistical package (p<0.05). For the neuropsychological parameter, the Trail Making Test (A) was the only test that showed significant difference for condition in the task execution time (p=0.026). Regarding the reaction time in the behavioral parameter, an interaction between both factors (p=0.034) was identified through a two-way-ANOVA (condition versus moment). Electrophysiological measures showed a significant interaction for electrodes: F7, F3, and FZ. CONCLUSIONS: The findings showed that LEV promotes an important cognitive enhancement in the executive functions.
RESUMEN
Quality of life has become an important yardstick of the impact on health. Its evaluation related to diseases and associated risk factors has increased in the population in general. This article seeks to assess the quality of life and the presence of the association with risk factors for non-communicable chronic diseases in the urban population of the city of Montes Claros in the State of Minas Gerais. It is a population-based cross-sectional study. The sample was calculated considering the prevalence of risk factors of overweight of 30% and corrected for a variation of 30%. Cluster sampling was conducted on urban census sectors. Seventeen census sectors were selected and 648 residents aged e" 18 years were interviewed. The risk factors for non-communicable chronic diseases as well as the quality of life were verified using the SF-36 questionnaire. Some risk factors were associated with the lowest scores on the SF-36 questionnaire. The presence of some risk factors for chronic diseases has an impact on quality of life.
Asunto(s)
Enfermedad Crónica/epidemiología , Calidad de Vida , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Factores de Riesgo , Adulto JovenRESUMEN
A qualidade de vida tornou-se uma importante medida de impacto em saúde. Sua avaliação relacionada às doenças e seus fatores de risco tem acrescido na população em geral. Objetivo: Verificar a qualidade de vida e a presença de associação com fatores de risco para as doenças crônicas não transmissíveis na população urbana do município de Montes Claros, Minas Gerais. Métodos: Estudo transversal de base populacional. A amostra foi calculada considerando-se a prevalência do fator de risco sobrepeso de 30% e corrigida para um efeito de delineamento de 30%. Amostragem por conglomerados de setores censitários urbanos. Sorteou-se 17 setores censitários e entrevistou-se 648 moradores de idade maior ou igual a 18 anos. Os fatores de risco para as doenças crônicas não transmissíveis foram verificadas e a qualidade de vida também através do SF-36. Resultados: Alguns dos fatores de risco foram associados a piores escores no questionário SF-36. Conclusão: a presença de alguns fatores de risco para as doenças crônicas tem impacto na qualidade de vida.
Quality of life has become an important yardstick of the impact on health. Its evaluation related to diseases and associated risk factors has increased in the population in general. This article seeks to assess the quality of life and the presence of the association with risk factors for non-communicable chronic diseases in the urban population of the city of Montes Claros in the State of Minas Gerais. It is a population-based cross-sectional study. The sample was calculated considering the prevalence of risk factors of overweight of 30% and corrected for a variation of 30%. Cluster sampling was conducted on urban census sectors. Seventeen census sectors were selected and 648 residents aged e" 18 years were interviewed. The risk factors for non-communicable chronic diseases as well as the quality of life were verified using the SF-36 questionnaire. Some risk factors were associated with the lowest scores on the SF-36 questionnaire. The presence of some risk factors for chronic diseases has an impact on quality of life.