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J Obstet Gynaecol Res ; 50(7): 1268-1272, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38720638

RESUMEN

Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P-aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment.


Asunto(s)
Síndrome Hemolítico Urémico Atípico , Humanos , Femenino , Embarazo , Síndrome Hemolítico Urémico Atípico/terapia , Síndrome Hemolítico Urémico Atípico/diagnóstico , Adulto , Intercambio Plasmático , Anticuerpos Monoclonales Humanizados/uso terapéutico , Anticuerpos Monoclonales Humanizados/administración & dosificación , Complicaciones Hematológicas del Embarazo/terapia , Complicaciones Hematológicas del Embarazo/diagnóstico
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