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Infection ; 40(1): 87-91, 2012 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21735108

RESUMEN

A 38-year-old male German traveller returning from Asia presented with fever, night sweats and abdominal complaints. Abdominal ultrasonography revealed several fast-growing abscesses of the liver. Three blood cultures as well as serologic investigations for the detection of antibodies to Entamoeba histolytica, performed on day 3 and 7 after the onset of clinical symptoms, remained negative. Stool microscopy revealed the presence of amoeba cysts compatible with E. histolytica infection. Taking both the amoebic and bacterial etiology of the abscesses into consideration, the patient was treated with metronidazole and ciprofloxacin followed by paromomycin. Antibodies to E. histolytica tested positive shortly after anti-amoebic therapy was initiated. The patient fully recovered, and ultrasound follow-up showed complete resolution of the abscesses within 50 days. This case leads to the conclusion that amoebic liver abscess should be considered despite negative amoeba serology and that ultrasonography is an important diagnostic tool for the early diagnosis of extraintestinal amoebiasis.


Asunto(s)
Antiprotozoarios/uso terapéutico , Entamebiasis/diagnóstico , Absceso Hepático Amebiano/diagnóstico , Administración Oral , Adulto , Pruebas de Aglutinación , Antígenos de Protozoos/aislamiento & purificación , Ciprofloxacina/uso terapéutico , Entamoeba histolytica/aislamiento & purificación , Entamebiasis/tratamiento farmacológico , Entamebiasis/parasitología , Entamebiasis/patología , Técnica del Anticuerpo Fluorescente , Alemania , Humanos , Técnicas para Inmunoenzimas , Hígado/diagnóstico por imagen , Hígado/parasitología , Hígado/patología , Absceso Hepático Amebiano/tratamiento farmacológico , Absceso Hepático Amebiano/parasitología , Absceso Hepático Amebiano/patología , Masculino , Metronidazol/uso terapéutico , Paromomicina/uso terapéutico , Ultrasonografía
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