[A vaccine against tetanus with a higher level of tetanus toxoid]. / Vakcína proti tetanu s vyssím obsahom tetanického anatoxínu.

In an immunological survey of the population it was revealed that the population above 60 years is not adequately protected against tetanus. This is probably to a considerable extent due to changes in the immune system as a result of age-conditioned changes and also due to an inadequate stimulus in the form of vaccine. The author prepared therefore an anti-tetanus vaccine with a higher antigen content. After its administration to a group of elderly subjects experimental evidence was provided of its favourable effect on the formation of tetanic antitoxin. The main attention was focused on the effect of vaccine in prophylaxis of tetanus after injuries.