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1.
BMC Oral Health ; 24(1): 617, 2024 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-38807096

RESUMEN

BACKGROUND: Retrieval of cement-retained implant-supported restorations is intriguing in cases of screw loosening. Detecting the estimated size of the screw access hole (SAH) could decrease destruction to the prosthesis and preserve the crown. OBJECTIVES: To precisely localize loose implant screws through cemented crowns to reduce crown damage after screw loosening. MATERIALS AND METHODS: In this in vitro study, 60 cement-retained implants supported 30 zirconia-based, and 30 ceramics fused to metal (CFM) lower molar crowns were invented, and each was subdivided into three subgroups (10 each). In group I (AI/BI) (control), SAH was created with the aid of orthopantomography (OPG). In contrast, in group II (zirconia-crown), SAH was created with the aid of CBCT + 3D printed surgical guide with a 2 mm metal sleeve in subgroups IIA/IIIA and CBCT + MAR was used to develop SAH in subgroups IIB/IIIB. SEM and Micro-CT scanned the SAH openings to determine the diameter of the hole, cracking, chipping, and chipping volume. RESULTS: Regarding the effect of plane CBCT and CBCT + MAR on prepared crowns, a highly significant association between group I with group II (p = 0.001) and group III (p = 0.002) was detected. Regarding the cracking of SAH, significant differences between the zirconium crown and CFM restoration (p = 0.009) were found, while for the chipping, no significant association was seen between groups (p = 0.19). CONCLUSIONS: CBCT, either as a plane CBCT or with MAR, significantly improved the accuracy of drilling the screw channel and decreased injury to the existing restoration and abutment, aiding in better localization of SAH in loosened implant abutment screws.


Asunto(s)
Coronas , Prótesis Dental de Soporte Implantado , Técnicas In Vitro , Humanos , Fracaso de la Restauración Dental , Microtomografía por Rayos X , Cementos Dentales , Tomografía Computarizada de Haz Cónico , Cementación/métodos , Circonio , Microscopía Electrónica de Rastreo , Tornillos Óseos
2.
JSES Int ; 7(6): 2507-2516, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37969506

RESUMEN

Background: Superior inclination of the base plate in reverse shoulder arthroplasty (RSA) is underestimated and may lead to major setbacks in terms of functional outcomes due to the altered biomechanics. Joint instability, scapular notching, and loosening of the glenoid component are considered the most serious sequelae. Therefore, a thorough preoperative radiological assessment of the affected shoulder joint and customized design of the prosthesis according to the glenoid morphology are decisive and directly correlated to the outcome. In this article, we propose a simple radiographic technique to assess the inclination of the glenoid preoperatively, which identifies the need for intraoperative correction. Materials and Methods: One hundred inconspicuous shoulder radiographs were included in the control group (CG) to define the normal ranges of the base plate orientation angle (BOA) and the base plate correction angle (BCA). Further, both angles were measured on 2-dimensional (2D) computed tomography scans of patients with proximal humerus fractures as well as radiographs, 2D and 3-dimensional (3D) computed tomography scans of patients with cuff tear arthropathy who underwent RSA between 2018 and 2021. The interobserver reliability among three independent testers was evaluated by calculating the intraclass correlation coefficient. In cuff tear arthropathy cases, the BOA and BCA measurements on different imaging modalities were compared using the Wilcoxon test. Possible variations of both angles' values based on glenoid erosion types, according to the Favard classification, were also investigated. Results: Regardless of the imaging modality used, the interobserver reliability was excellent among three independent observers. In the CG, the mean BOA and BCA values were 118° ± 6° and 17° ± 5°, respectively. The mean corrected BOA values of the CG and fracture group were 136° ± 5° and 140° ± 5°, respectively. In contrast to the BCA values, the BOA measurements on radiographs showed a statistically significant difference compared to those obtained on 2D- and 3D scans in the cuff arthropathy group. Further, both angles' values varied according to the extent and location of the glenoid erosion. The lowest mean BOA and highest mean BCA values were observed in cases with Favard glenoid type E3. Conclusions: The BOA and the BCA are reliable tools proposed to aid in precisely positioning the glenoid component in RSA in the preoperative setting. Whereas, the BOA determines the inclination of the inferior glenoid segment, the BCA represents the extent of correction required to obtain a neutral inclination of the base plate. Glenoid type E3 of the Favard classification with superior wear is particularly susceptible to base plate superior tilt.

3.
Front Psychiatry ; 14: 1212769, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37599883

RESUMEN

Introduction: The COVID-19 pandemic has been shown to cause enormous psychological burden among health care workers, including first responders. However, the psychological well-being of first responders, essential in the fight against COVID-19 pandemic, has often been ignored. This qualitative study aimed to explore the coping strategies used by EMTs to manage stress during the pandemic. Methods: The research was designed as a qualitative study, utilizing a thematic analysis framework. Semi-structured interviews were conducted with 15 EMTs from a single geographic area between September 2022 and December 2022. The data were analyzed using Braun and Clarke analytic techniques, and this study used Lincoln and Guba's to assess the reliability of the data. Results: Four main coping strategies emerged from the data: seeking social support, practicing self-care, utilizing coping mechanisms, and finding meaning and purpose in work. EMTs sought support from both professional and personal sources, engaged in physical and emotional self-care, used humor and distraction as coping mechanisms, and found meaning and purpose in helping others and growing as professionals. Conclusion: Based on the extracted results from the study on EMTs in Iran, it can be concluded that the importance of social support cannot be overstated, as it serves as a crucial buffer against the negative effects of stress and trauma. The findings suggest that addressing the social and emotional needs of EMTs is important for promoting their mental health and well-being during the pandemic.

5.
J Educ Health Promot ; 12: 449, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38464660

RESUMEN

INTRODUCTION: One of the most important wards of the hospital is the emergency department (ED). Due to the increasing number of referrals, overcrowding has become a significant problem. It means an increase in patients' referrals and swarms at the ED, limiting their medical staff access. This study investigates the nurses' experiences and perceptions about the reasons for ED overcrowding. MATERIALS AND METHODS: Twelve emergency nurses were purposefully selected to take part in this study. Data collection was through face-to-face semi-structured interviews until data saturation was finalized. Data analysis was conducted using Graneheim and Lundman's conventional content analysis. RESULTS: Nurses' experiences with the reasons for ED overcrowding came into two main categories. The first was "increased referral to the emergency department," which had three subcategories: "increased referral due to health system reform plan," "increased referral due to corona pandemic," and "improper triage." The second was "increased patients' length of stay at the ED" with seven subcategories including "shortage of bed," "shortage of nursing staff," "lack of physical space," "turtle para-clinic," "on-call specialists' delay," "timely medical record documentation requirements," and "delaying in patients' transfer from the ED to the ward." CONCLUSION: The results showed ED overcrowding is inevitable. Intentional or unintentional changes in the health system, such as implementing the health system reform plan or the corona pandemic, can also increase overcrowding. Findings showed ED overcrowding increased referrals and patients' length of stay. This study suggests the health system authorities pay more attention to this phenomenon and look for solutions.

6.
J Orthop ; 34: 357-363, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36247826

RESUMEN

Objectives: The radiological measurement of the Böhler angle (BA) and the critical angle of Gissane (CAG) is used not only to diagnose and corroborate the suspicion of the presence of calcaneal fractures but also to assess the prognosis of different injury patterns and to evaluate the operative reduction of calcaneal fractures. Notwithstanding, many previous studies indicated the poor intra- and interobserver reproducibility of both angles. In this retrospective study, we present the subtalar calcaneal angle (SCA) as an additional diagnostic tool -to BA and CAG-which can be applied on pre- and postoperative radiographs to assess calcaneal fractures involving the posterior facet. Design: Retrospective Study. Methods: Two retrospective groups were established, a 'CF-group' including radiographs of patients diagnosed with a calcaneal fracture and underwent operative treatment in the authors' traumatology department, and a 'control group' with 50 lateral calcaneal radiographs clear of skeletal lesions. Initially, the SCA, BA, and CAG were measured in both groups by three examiners. Those measurements were repeated one month later. The intra- and intertester reliabilities of all three angles were tested by determining the intraclass correlation coefficient (ICC). A paired t-test was used to prove the statistically significant difference between the SCA values for the pre- and postoperative groups, while the significant difference between the SCA values for the control and preoperative groups was tested through an independent-samples t-test. Results: The intra- and interobserver reliability of the SCA and the BA was in close proximity. The values of the SCA in both the control and postoperative groups were significantly different compared to the measurements of the preoperative group. The CAG showed poor intertester reliability. Conclusion: The subtalar calcaneal angle is a new instrument with proven reliability in estimating the prognosis of displaced calcaneal fractures and the postoperative alignment of the posterior facet. Level of clinical evidence: Diagnostic, Level III.

7.
Curr Pharm Biotechnol ; 23(15): 1893-1902, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35135450

RESUMEN

BACKGROUND: In the wake of the warning by WHO that the prevalence of dementia may have a rise of 125% in the Middle East by 2050, identification of the genetic risk factors in Arab populations is urgent. OBJECTIVES: To investigate the association of Single Nucleotide Polymorphisms (SNPs) in apolipoprotein E (ApoE), clusterin (CLU), tumor necrotic factor- α (TNF-α) and interleukin-6 (IL-6) genes, with risk of Alzheimer's disease (AD) in Saudi Arabian participants. METHODS: A total of 42 Saudi AD patients and 23 age-matched control participants were genotyped for eight SNPs: rs429358, rs7412 (ApoE); rs11136000, rs1532278 (CLU); rs1800629, rs1799724 (TNF-α) and rs1800796, rs1800795(IL-6), by RT-PCR using the TaqMan assay. Serum concentrations of amyloid beta peptide 1-40(Aß1-40), amyloid beta peptide 1-42(Aß1- 42), CLU and some other biochemical markers were measured. RESULTS: A significant increase (p=0.004) in the serum CLU level was detected in the AD group (340.4 ± 74.6) compared with control group (265.0 ± 80.9). For rs1532278 (CLU), genotype GA was significantly higher in AD patients (57.1%) than in the control participants (26.1%), [p=0.024, OR = 4.00, 95% CI (1.20-13.28)]. For the ApoE SNP rs7412, 40.4% of patients carried a TT genotype, whereas it was completely absent in the controls [p = 0.020, OR = 30.53, 95% CI (1.73 - 540.05)].For rs429358 (ApoE), patients showed a significantly increased frequency of the TC genotype [p = 0.006, OR = 9.33, 95% CI (1.89-46.19)] and TT [p = 0.045, OR = 19.76, 95% CI (1.07-366.0)] genotype than controls. AD patients with CC genotype for ApoE rs429358 had significantly lower levels of Aß1-40 (p=0.04) in AD patients than controls. Carriers of genotype GG for rs1800629 (TNF-α) showed significantly higher levels of serum IL-6 (p = 0.04) in AD patients. CONCLUSION: Genetic variants in ApoE and CLU may influence susceptibility to AD among Saudi Arabian participants.


Asunto(s)
Enfermedad de Alzheimer , Clusterina , Anciano , Humanos , Enfermedad de Alzheimer/genética , Péptidos beta-Amiloides , Apolipoproteínas E/genética , Biomarcadores , Clusterina/genética , Interleucina-6/genética , Arabia Saudita/epidemiología , Factor de Necrosis Tumoral alfa/genética
8.
Biology (Basel) ; 11(2)2022 Feb 11.
Artículo en Inglés | MEDLINE | ID: mdl-35205153

RESUMEN

Angiogenin (ANG), a multifunctional protein known to induce blood vessel formation, is a potential biomarker for cardiovascular diseases; however, whether it is affected by vitamin D supplementation is not known. This interventional study in vitamin D-deficient Saudi adults was designed to investigate it. A total of 100 vitamin D-deficient Saudi adults aged 30-50 years were randomly selected to undergo 6-month vitamin D supplementation. Circulating levels of fasting glucose, lipids, vitamin D, apolipoproteins (AI, AII, B, CI, CII, CIII, E, and H), and ANG were measured using commercially available assays at baseline and after six months. Overall, vitamin D levels increased significantly post intervention. With this, levels of apo-CIII and apo-E significantly increased (p-values of 0.001 and 0.009, respectively) with a significant parallel decrease in apo-B (p = 0.003). ANG levels were significantly positively associated with most apolipoproteins and inversely correlated with HDL-cholesterol. Post intervention, the changes in ANG levels were positively correlated with apo-E (r = 0.32; p < 0.01 in all subjects and r = 0.40; p < 0.05 in males). Vitamin D supplementation may modestly affect ANG levels. The association observed between ANG and apo-E is worthy of further investigation since both biomarkers have been linked to neurodegenerative disorders.

9.
J Educ Health Promot ; 10: 347, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34761033

RESUMEN

BACKGROUND: In the turbulent and stressful work environment of prehospital emergencies, the conflict among emergency medical technicians (EMT) and other health-care providers is inevitable. This study aims to examine the concept of workplace interpersonal conflict (WIC) in prehospital emergencies. MATERIALS AND METHODS: The eight-step Walker and Avant's concept analysis approach was adopted to define the concept. Iranmedex, SID, Magiran, ISC, PubMed, Scopus, Embase, and Web of Science searched with keywords such as WIC and hospital emergencies. After an extensive review of online national and international databases, one dictionary, nine books, and 25 articles in English and Persian were retrieved for the purposes of the study. RESULTS: The antecedents, attributes, and consequences of the concept identified. EMT must learn how to eliminate their destructive effects while enhancing constructive effects. CONCLUSION: Conflict is an inevitable part of life, and EMT must learn how to reduce their destructive effects while increasing constructive results.

10.
Ethiop J Health Sci ; 31(6): 1115-1124, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35392330

RESUMEN

Background: Exploring emergency medical technicians' (EMTs) experiences of COVID-19 epidemic, help to identify the challenges they face in their daily work and develop strategies that address these challenges. This study aimed to explore EMTs' experiences of the challenges of prehospital care delivery during the COVID-19 pandemic. Methods: This qualitative study was conducted in March-July 2020 using conventional content analysis approach. Fifteen EMTs were purposively selected from the Emergency Medical Services (EMS) Center in Qom, Iran. For data collection, semi-structured interviews were conducted until data saturation was reached. Results: EMTs' experiences of the challenges of prehospital care delivery during the COVID-19 pandemic were classified into three main categories including "restless society", "difficult care delivery conditions", and "unprepared organization". The emergent subcategories were "need for information", "limited perception of the COVID-19 risk", "obsessive use of disinfectants", "fear over the transmission of COVID-19 to self and others", "burnout due to heavy workload", "altered communication with hospital staff", "ethical conflicts", "lack of a definite treatment plan", "lack of protective equipment", "staff shortage due to the affliction of EMTs by COVID-19", and "inadequate support by authorities". Conclusion: During COVID-19 pandemics, EMTs face many challenges including emotional and occupational stress, social strains, risk of affliction by infections, heavy workload, and ethical conflicts and hence, experience difficulties in quality care delivery. Developing appropriate strategies, guidelines, and policies are needed to effectively manage these challenges and improve the quality of prehospital care delivery in COVID-19 epidemic.


Asunto(s)
COVID-19 , Servicios Médicos de Urgencia , Auxiliares de Urgencia , COVID-19/epidemiología , Humanos , Pandemias , SARS-CoV-2
11.
Clin Case Rep ; 8(6): 1061-1064, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32577265

RESUMEN

A 43-year-old man who was treated with interferon-beta for multiple sclerosis was presented with hypertension, headache, nausea/vomiting, blurred vision, and renal dysfunction. The treatment with drugs and dialysis relieved the symptoms. Despite plasmapheresis is known to cause improvement in renal function, no such improvement was seen in patient.

12.
Public Health Nutr ; 23(7): 1208-1213, 2020 05.
Artículo en Inglés | MEDLINE | ID: mdl-31097054

RESUMEN

OBJECTIVE: Both vitamin D and Fe micronutrient deficiencies are common in Saudi Arabia but the association between them is unclear. The present study aimed to determine whether Fe indices are associated with vitamin D status and other metabolic markers in Arab adolescents. DESIGN: Single-centre, cross-sectional study gathering anthropometrics, glucose and lipid profile. Serum 25-hydroxyvitamin D (25(OH)D), Fe, total iron-binding capacity (TIBC), transferrin saturation (%) and other parameters were measured. SETTING: Vitamin D School Project Database, King Saud University (2014-2016). PARTICIPANTS: Arab adolescents aged 10-17 years randomly selected from the Vitamin D School Project Database (170 Saudi students; 100 girls, seventy boys). RESULTS: Among Fe indices, only TIBC was found to be significantly and inversely associated with 25(OH)D (r = -0·20; P < 0·01) and only in girls (r = -0·20; P < 0·05). Among cardiometabolic parameters, serum Fe was associated with TAG in boys (r = 0·36; P < 0·01) and inversely associated with HDL-cholesterol in girls (r = -0·29; P < 0·05). Age was the most significant predictor of serum Fe for all participants, accounting for 5 % (R2 = 0·05; P = 0·004) of variance perceived. Serum 25(OH)D and age, on the other hand, were the most significant predictors for TIBC, accounting for 10·1 % (R2 = 0·10; P < 0·001) of variance perceived. CONCLUSIONS: Among healthy Arab adolescents, the association between vitamin D and Fe indices, particularly TIBC, is modest, inverse and sex-dependent. Larger studies with inclusion of markers such as hepcidin and ferritin, vitamin D metabolites and endogenous sex hormones may provide a clearer view of this complex association.


Asunto(s)
Anemia Ferropénica/sangre , Hierro/sangre , Deficiencia de Vitamina D/sangre , Vitamina D/sangre , Adolescente , Anemia Ferropénica/epidemiología , Árabes , Glucemia , Niño , HDL-Colesterol/sangre , Estudios Transversales , Femenino , Humanos , Lípidos/sangre , Masculino , Estado Nutricional , Arabia Saudita/epidemiología , Factores Sexuales , Vitamina D/análogos & derivados , Deficiencia de Vitamina D/epidemiología
13.
SICOT J ; 5: 16, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31115316

RESUMEN

INTRODUCTION: Hip arthroscopy for treatment of femoroacetabular impingement (FAI) has shown significant pain and functional improvement. However, the differential outcome of each of the FAI morphological types in contrast to one another remains largely unknown. This study was conducted to detect a possible difference in outcome among different FAI types treated using hip arthroscopy. METHODS: In this prospective non randomized comparative study, after exclusion of non-FAI cases and cases with advanced arthritic changes, 90 hips in 85 patients that had hip arthroscopy for the treatment of FAI between 2011 and 2015 in our center were analyzed. The collected patient reported outcome measures (PROMs) included visual analog scale (VAS) of pain, the modified Harris hip score (mHHS), and the non arthritic hip score (NAHS) both preoperatively and at final follow-up. Patient satisfaction was collected at final follow-up. Postoperative PROMs were subjected to three main comparisons based on each of FAI type, labral procedure, and extent of cartilage damage. Repeat comparison based on FAI type after matching of exact chondrolabral condition was also attempted. RESULTS: Mean follow-up was 32.8 months (five patients lost from follow-up). There was a significant improvement in the overall PROMs. This improvement was significantly higher in the cam group in contrast to the mixed group. After matching for chondrolabral condition, this difference was consistent and more evident. DISCUSSION: The outcome of arthroscopic treatment of pure cam FAI is significantly better than that of mixed FAI. Matching of the same chondrolabral condition and repeating the comparison yields similar results.

14.
J Cosmet Dermatol ; 18(1): 204-211, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29577562

RESUMEN

BACKGROUND: Dermatologic complications are common in patients with end-stage renal disease and also have a high diversity. OBJECTIVES: This meta-analysis reviews prevalence of dermatological manifestations among hemodialysis patients in Iran. MATERIALS AND METHODS: Using PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS as the main international electronic data sources, and Iran-Medex, Irandoc, and Scientific Information Database, as the main domestic databases with systematic search capability, we systematically searched surveys, papers, and reports on the prevalence of dermatological manifestations (until February 2016). Heterogeneity of reported prevalence's between studies was assessed using the Q test; overall prevalence of dermatological manifestations was estimated using random-effect meta-analysis model. RESULTS: We found 1229 records; from them, a total of eight studies comprising 917 hemodialysis patients were included. In all of studies, skin discoloration, pruritus and xerosis have the highest prevalence. According to random-effect meta-analysis model, the pooled prevalence of skin discoloration, pruritus, ecchymosis, xerosis, and half-and-half nail in hemodialysis patients were 48.03% (95% CI: 45.09-51.01), 52.85% (95%CI: 49.23-56.47), 19.88 (95% CI: 17.57-22.19), 51.14% (95% CI: 48.25-54.02), and 18.50% (95% CI: 16.0-21.0), respectively. CONCLUSIONS: his study shows that the prevalence of dermatological manifestations seems high among the hemodialysis patients in Iran, and skin discoloration, pruritus, and xerosis are more common.


Asunto(s)
Fallo Renal Crónico/terapia , Diálisis Renal , Enfermedades de la Piel/epidemiología , Equimosis/epidemiología , Humanos , Irán/epidemiología , Enfermedades de la Uña/epidemiología , Trastornos de la Pigmentación/epidemiología , Prevalencia , Prurito/epidemiología
15.
Clin Nutr ; 38(4): 1561-1569, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-30170781

RESUMEN

OBJECTIVE: The aim of this trial was to characterize the beneficial effects of probiotics on decreasing endotoxin levels and other cardiometabolic parameters in Arab patients with type 2 diabetes mellitus (T2DM). METHODS: Saudi adults with naïve T2DM (n = 30; 12 males and 18 females) were randomly allocated to receive twice daily placebo or 2.5 × 109 cfu/g of Ecologic®Barrier (multi-strain probiotics; n = 31; 14 males and 17 females) in a double-blind manner over a 6 month period, respectively. Anthropometrics were measured and fasting blood samples were collected to analyze endotoxin, glycemic parameters [glucose, insulin, c-peptide and homeostasis model assessment for insulin resistance (HOMA-IR)], lipids [triglycerides, total cholesterol, low and high-density lipoprotein (LDL and HDL, respectively) cholesterol and total/HDL-cholesterol ratio], inflammatory markers [tumor-necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and C-reactive protein (CRP)] and adipocytokines [leptin, adiponectin and resistin] at baseline and after 3 and 6 months of intervention. RESULTS: Multi-strain probiotics supplementation for 6 months caused a significant decrease in circulating levels of endotoxin by almost 70% over 6 months, as well as glucose (38%), insulin (38%), HOMA-IR (64%), triglycerides (48%), total cholesterol (19%), total/HDL-cholesterol ratio (19%), TNF-α (67%), IL-6 (77%), CRP (53%), resistin (53%), and a significant increase in adiponectin (72%) as compared with baseline. Only HOMA-IR had a clinically significant reduction (-3.4, 64.2%) in the probiotics group as compared to placebo group at all time points. No other clinically significant changes were observed between the probiotic or placebo group at 3 and 6 months in other markers. CONCLUSION: Multi-strain probiotic supplementation over 6 months as a monotherapy significantly decreased HOMA-IR in T2DM patients, with the probiotic treatment group highlighting reduced inflammation and improved cardiometabolic profile. As such, multi-strain probiotics is a promising adjuvant anti-diabetes therapy. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01765517.


Asunto(s)
Glucemia/efectos de los fármacos , Diabetes Mellitus Tipo 2 , Endotoxinas/sangre , Inflamación/sangre , Probióticos , Adipoquinas/sangre , Diabetes Mellitus Tipo 2/dietoterapia , Diabetes Mellitus Tipo 2/metabolismo , Método Doble Ciego , Femenino , Humanos , Insulina/sangre , Resistencia a la Insulina/fisiología , Lípidos/sangre , Masculino , Placebos , Probióticos/administración & dosificación , Probióticos/farmacología , Probióticos/uso terapéutico
16.
Nutrients ; 10(12)2018 Dec 02.
Artículo en Inglés | MEDLINE | ID: mdl-30513812

RESUMEN

Vitamin D deficiency has been shown to affect iron status via decreased calcitriol production, translating to decreased erythropoiesis. The present study aimed to determine for the first time whether vitamin D supplementation can affect iron levels among Arab adolescents. A total of 125 out of the initial 200 Saudi adolescents with vitamin D deficiency (serum 25(OH)D < 50 nmol/L) were selected from the Vitamin D-School Project of King Saud University in Riyadh, Saudi Arabia. Cluster randomization was done in schools, and students received either vitamin D tablets (1000 IU/day) (N = 53, mean age 14.1 ± 1.0 years) or vitamin D-fortified milk (40IU/200mL) (N = 72, mean age 14.8 ± 1.4 years). Both groups received nutritional counseling. Anthropometrics, glucose, lipids, iron indices, and 25(OH)D were measured at baseline and after six months. Within group analysis showed that post-intervention, serum 25(OH)D significantly increased by as much as 50%, and a parallel decrease of -42% (p-values <0.001 and 0.002, respectively) was observed in serum iron in the tablet group. These changes were not observed in the control group. Between-group analysis showed a clinically significant increase in serum 25(OH)D (p = 0.001) and decrease in iron (p < 0.001) in the tablet group. The present findings suggest a possible inhibitory role of vitamin D supplementation in the iron indices of healthy adolescents whose 25(OH)D levels are sub-optimal but not severely deficient, implying that the causal relationship between both micronutrients may be dependent on the severity of deficiency, type of iron disorder, and other vascular conditions that are known to affect hematologic indices. Well-designed, randomized trials are needed to confirm the present findings.


Asunto(s)
Árabes , Hierro/sangre , Vitamina D/administración & dosificación , Adolescente , Fenómenos Fisiológicos Nutricionales de los Adolescentes , Animales , Calcitriol/fisiología , Estudios de Cohortes , Suplementos Dietéticos , Femenino , Alimentos Fortificados , Educación en Salud , Humanos , Hierro/análisis , Deficiencias de Hierro , Masculino , Leche , Estado Nutricional/fisiología , Arabia Saudita , Vitamina D/análogos & derivados , Vitamina D/sangre , Deficiencia de Vitamina D/fisiopatología
17.
Prehosp Disaster Med ; 33(6): 602-606, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30376910

RESUMEN

BACKGROUND: The contamination of the environment, ambulance equipment, and staff hands consequently are major factors which create nosocomial infections in emergency patients. The contamination of equipment and devices plays an important role in nosocomial infections. OBJECTIVES: The aim of this study was to determine the effectiveness of a disinfectant on the rate of microbial contamination of ambulances in Qom Emergency Medical Services (EMS), Qom, Iran. METHODS: This is a quasi-experimental study with a before-after design in order to determine microbial contaminations at the rear and front cabin of ambulances, as well as medical equipment being utilized in Qom EMS. Saya sept-HP-2% solution was used for disinfection. Bacteriological standard methods were used to identify the contaminations. RESULTS: The contamination rates before and after use of disinfection solution were 52% and eight percent, respectively. Coagulase-negative staphylococci were the most commonly isolated bacterial agent from the equipment (53%). In all equipment, the contamination level has shown a significant reduction after applying disinfectant. CONCLUSIONS: In spite of the fact that the rate of infection from ambulance equipment is high, the results showed that the use of the suitable disinfectant had an effective role in the reduction of bacteria. FarhadlooR, Goodarzi FarJ, AzadehMR, ShamsS, Parvaresh-MasoudM. Evaluation of bacterial contamination on prehospital ambulances before and after disinfection. Prehosp Disaster Med. 2018;33(6):602-606.


Asunto(s)
Ambulancias , Infección Hospitalaria/prevención & control , Desinfección , Servicios Médicos de Urgencia/normas , Contaminación de Equipos , Humanos , Irán
18.
Artículo en Inglés | MEDLINE | ID: mdl-30258552

RESUMEN

Moral distress is among the various types of distress that involves nurses and can lead to multiple complications. It is therefore rather important to identify the factors related to moral distress. The purpose of this study was to examine the relationship between futile care perception and moral distress among intensive care unit (ICU) nurses. This cross-sectional study used a descriptive-correlation method and was conducted on 117 ICU nurses of Qom hospitals in 2016. Data were collected using a 17-item futile care perception questionnaire, and Jameton's moral distress questionnaire containing 30 questions. Data analysis was performed using SPSS 16, descriptive statistics and univariate regression analysis. The results showed that the mean age of the participants was 34.99, and most (about 66.7%) were women. Univariate regression analysis indicated that when ICU nurses' perception of futile care and work experience increased, their moral distress also increased significantly (P = 0.03 and P = 0.02, respectively). It can therefore be concluded that moral distress is associated with futile care and ICU work experience. It seems that some interventions are necessary in future to place nurses in clinical situations involving futile care, and thus reduce their level of moral distress.

19.
Saudi J Biol Sci ; 25(4): 710-714, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29740234

RESUMEN

Spexin (SPX) is a novel biomarker abundantly expressed in several animal and human tissues implicated in food intake and glucose control, respectively. As new roles for SPX are emerging, the present study explored for the first time, the associations of SPX to several cardiometabolic indices and inflammatory markers in pregnant women, a demographic not yet investigated with respect to SPX. A total of 117 Saudi women subdivided to those with gestational diabetes mellitus (GDM) (N = 63) and those without (N = 54) were included in this cross-sectional study. Anthropometry, glycemic, lipid, vitamin D, adipocytokines and inflammatory markers were measured consecutively at baseline and after the 2nd and 3rd trimesters. Age- and BMI adjusted comparisons revealed that levels of SPX were not significantly different in pregnant women with and without GDM. In all subjects, circulating levels of SPX showed modest associations with glucose (R = 0.18; p = .08) and HOMA ß (R = -0.19; p = .09) as well as significant positive associations with total cholesterol (R = 0.25; p = .02), LDL-cholesterol (R = 0.25; p = .02), 25(OH)D (R = 0.22; p = .04), albumin (R = 0.30; p < .01) and IL1ß (R = 0.41; p < .01). Stepwise regression analysis also suggested that IL1ß, leptin and albumin were the significant predictors of SPX. In summary, SPX levels modestly affect glucose and insulin sensitivity in pregnant women but is not associated with GDM and obesity. The significant association of SPX to ILß warrants further investigation as to the role of SPX in immune modulation.

20.
Prehosp Disaster Med ; 33(2): 227, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-29482666

RESUMEN

Parvaresh-Masoud M , Asayesh H . Bus crashes in Iran. Prehosp Disaster Med. 2018;33(2):227-227.


Asunto(s)
Accidentes de Tránsito , Vehículos a Motor , Traumatismo Múltiple , Humanos , Irán , Factores de Riesgo
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