Macroadenoma del epitelio no pigmentado del cuerpo ciliar / Macroadenoma of the non-pigmented ciliary epithelium

CASO CLÍNICO: Se describen los hallazgos clínicos y la cirugía conservadora de un paciente con un adenoma no pigmentado del cuerpo ciliar. El adenoma presentaba un tamaño de 5 × 7 mm. El paciente fue intervenido con una cirugía conservadora mediante iridociclectomía parcial asociada a esclerouvectomía lamelar. DISCUSIÓN: Los adenomas del cuerpo ciliar clínicamente pueden imitar a los melanomas amelanóticos. La cirugía conservadora del globo ocular permite realizar un diagnóstico y un tratamiento del paciente manteniendo la función visual

CASE REPORT: We report the clinical features and surgery of a patient with an adenoma of the non-pigmented ciliary epithelium. The adenoma measured 5 × 7 mm. The patient underwent radical ocular surgery consisting of partial iridocyclectomy associated to lamellar sclerouvectomy. DISCUSSION: Adenomas of ciliary body can mimic clinically amelanotic melanomas. We present details of the patient's medical records and review the literature. Clinically, adenoma in ciliary body can mimic amelanotic melanomas. Conservative surgery of the eye allows diagnosis and treatment, maintaining visual function

[Macroadenoma of the non-pigmented ciliary epithelium]. / Macroadenoma del epitelio no pigmentado del cuerpo ciliar.

CASE REPORT: We report the clinical features and surgery of a patient with an adenoma of the non-pigmented ciliary epithelium. The adenoma measured 5 × 7 mm. The patient underwent radical ocular surgery consisting of partial iridocyclectomy associated to lamellar sclerouvectomy. DISCUSSION: Adenomas of ciliary body can mimic clinically amelanotic melanomas. We present details of the patient's medical records and review the literature. Clinically, adenoma in ciliary body can mimic amelanotic melanomas. Conservative surgery of the eye allows diagnosis and treatment, maintaining visual function.

New guidelines for the management of thyroid nodules and differentiated thyroid cancer.

AIM: The aim of this paper was to evaluate the diagnostic efficiency of cytology results obtained through fine-needle aspiration (FNA) in partially cystic thyroid nodules and to examine the association between specific ultrasonographic evidence and malignancy. METHODS: A descriptive, observational, cross-sectional study examining the relationship between cytological and ultrasonographic findings in a group of patients with partially cystic thyroid nodules. The following ultrasound characteristics were examined: 1) nodule size (in mm); 2) percentage of the solid portion of the nodule (greater or less than 50%); 3) echogenicity of the solid portion (hypoechoic, isoechoic, or hyperechoic); 4) eccentricity of the solid portion; 5) regularity of the margins, and 6) presence or absence of microcalcifications. RESULTS: The ultrasound (US) and cytological characteristics of the partially cystic thyroid nodules of 145 patients, 127 women with a mean age of 53.1 years (SD 19.7) and 18 men with a mean age of 60 (SD 19.7), were reviewed. The mean size of the nodules was 28.07 mm (SD 11.23). Thirty-seven (25.5%) were solitary nodules and 98 (72.59%) formed parts of multinodular goiters. Twenty-eight (19.3%) of the cytologies proved to be inadequate samples, 104 (71.7%) were benign, 7 (4.8%) were suspicious, and 4 (2.8%) were malignant. The sensitivity for detecting malignancy was >90% when the percentage of the solid portion of the nodule was greater than 50%; these values remained unchanged when combined with other sonographic findings. The greatest specificity for malignancy was associated with the presence of microcalcifications (99%); however, none of the associations observed were statistically significant. CONCLUSION: FNA cytology is an essential diagnostic tool in both partially cystic and solid nodules. Examination of several individual ultrasound characteristics of these nodules, such as the percentage of the solid component, as well as other common characteristics, including the echogenicity or the presence of microcalcifications, may greatly facilitate the diagnostic process.

[Nonbacterial thrombotic endocarditis: a review of a necropsy series]. / Endocarditis trombótica no bacteriana: revisión de una serie necrópsica.

Nonbacterial thrombotic endocarditis (NBTE) is characterized by the deposition of thrombi on undamaged heart valves and by the increased frequency of associated arterial embolic events in patients with chronic debilitating diseases. Fifteen subjects diagnosed by necropsy of nonbacterial thrombotic endocarditis (NBTE) were studied to evaluate the general features, associated diseases, arterial embolic events, distribution and characteristics of histologic lesions. The most common underlying disease was neoplasm, which was present in 10 cases. Of these, 6 were adenocarcinomas, 3 hematological, and the remaining case was a bladder carcinoma. Other associated diseases included amyloidosis, MELAS syndrome, and sepsis. In most cases peripheral arterial embolic events were detected (9 cases). The central nervous system and the lung were involved in 7 cases (78%), heart and kidneys in 5 cases (56%), and spleen in 4 cases (44%). Other involved organs included pancreas, thyroid gland, testicles, meninges, liver and adrenal glands. The left valves were predominantly involved. The mitral valve in eight cases and the aortic valve in six cases. All cases with right involvement had the antecedent of central venous catheterization. Subendothelial fibrosis was a common histological finding which revealed the chronicity of the disease.