RESUMEN
Although heat-related mortality has received considerable research attention, the impact of cold weather on public health is less well-developed, probably due to the fact that physiological responses to cold weather can vary substantially among individuals, age groups, diseases etc., depending on a number of behavioral and physiological factors. In the current work we use the classification techniques provided by the COST-733 software to link synoptic circulation patterns with excess cold-related mortality in 5 regions of England. We conclude that, regardless of the classification scheme used, the most hazardous conditions for public health in England are associated with the prevalence of the Easterly type of weather, favoring advection of cold air from continental Europe. It is noteworthy that there has been observed little-to-no regional variation with regards to the classification results among the 5 regions, suggestive of a spatially homogenous response of mortality to the atmospheric patterns identified. In general, the 10 different groupings of days used reveal that excess winter mortality is linked with the lowest daily minimum/maximum temperatures in the area. However it is not uncommon to observe high mortality rates during days with higher, in relative terms, temperatures, when rapidly changing weather results in an increase of mortality. Such a finding confirms the complexity of cold-related mortality and highlights the importance of synoptic climatology in understanding of the phenomenon.
Asunto(s)
Mortalidad , Estaciones del Año , Tiempo (Meteorología) , Frío , Inglaterra , Humanos , Programas InformáticosRESUMEN
An aberrant random amplified polymorphic DNA (RAPD) marker in genomic DNA of tissue culture plantlets was frequently observed during a comparison of DNA fingerprints derived from potato germplasm grown in tissue culture and the field. The RAPD marker was cloned, sequenced and determined to be of bacterial origin. A bacterial contaminant was isolated from the tissue culture plants and identified as a Bacillus pumilus. A set of sequence characterised amplified region (SCAR) primers were designed from the sequence of the cloned fragment and tested for the specific detection of B. pumilus. Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLPs) were also used to generate B. pumilus profiles specific to our isolate in order to test and confirm the sequence homology of amplified markers generated from a range of DNA samples isolated from tissue culture plants and pure isolates of B. pumilus-like bacteria.
Asunto(s)
Bacillus/genética , Enfermedades de las Plantas/microbiología , Solanum tuberosum/microbiología , Bacillus/aislamiento & purificación , Secuencia de Bases , Técnicas de Cultivo , ADN Bacteriano/química , ADN Bacteriano/genética , ADN Bacteriano/aislamiento & purificación , Datos de Secuencia Molecular , Reacción en Cadena de la Polimerasa , Polimorfismo de Longitud del Fragmento de Restricción , ARN Ribosómico 16S/genética , Técnica del ADN Polimorfo Amplificado Aleatorio/métodos , Sensibilidad y Especificidad , Análisis de Secuencia de ADN , Solanum tuberosum/genéticaRESUMEN
Winter ischaemic heart disease (IHD) mortality events (ME) were identified in order to establish their degree of meteorological sensitivity. Sensitivity was evaluated using regression of surface meteorological and large-scale atmospheric circulation variables on daily mortality for each mortality event. Critical meteorological variables affecting IHD mortality appear to be local surface dry-bulb and dew-point temperature and large-scale southerly and westerly wind components, atmospheric pressure and vorticity. The rate of change and departure from normal conditions of these variables appear to be especially important for engendering IHD mortality events. Associated with IHD mortality are two broad types of weather conditions: (1) blustery westerly flows and rapidly changing weather from the west and (2) climatologically strong northeasterly to southeasterly flows of cold air, which bring rapidly changing and anomalous thermal conditions to the study area. The general atmospheric circulation patterns that produce these conditions are identified and the implications of results for weather and health studies are discussed.
Asunto(s)
Isquemia Miocárdica/mortalidad , Tiempo (Meteorología) , Movimientos del Aire , Estudios Epidemiológicos , Humanos , Isquemia Miocárdica/etiología , Estaciones del Año , Reino Unido/epidemiologíaRESUMEN
A synoptic climatological approach is used to investigate linkages between air mass types (weather situations), the daily mean particulate matter with a size of 10 microns or less (PM10) concentrations and all respiratory hospital admissions for the Birmingham area, UK. Study results show distinct differential responses of respiratory admission rates to the six winter air mass types identified. Two of the three air masses associated with above average admission rates (continental anticyclonic gloom and continental anticyclonic fine and cold) also favour high PM10 levels. This association is suggestive of a possible linkage between weather, air quality and health. The remaining admissions-sensitive air mass type (cool moist maritime) does not favour high PM10 levels. This is considered to be indicative of a direct weather-health relationship. A sensitising mechanism is proposed to account for the linkages between air mass type, PM10 concentrations and respiratory response.
Asunto(s)
Enfermedades Respiratorias/epidemiología , Tiempo (Meteorología) , Aire , Hospitalización , Humanos , Estaciones del Año , Reino Unido/epidemiologíaRESUMEN
The current bioclimates of equatorial Western and tropical South Pacific have been assessed, using the concepts of effective temperature and relative strain as a basis for evaluating likely changes in human comfort regimes as a consequence of global warming. Current bioclimates may be considered marginally stressful for indigenous populations. Global warming will result in changes in the frequency, duration and intensity of physioclimatically stressful conditions.