RESUMEN
Epidural spinal electrostimulatory system (ESES) or dorsal column stimulation (DCS) may be used for the treatment of peripheral vascular diseases of the lower extremities. ESES has been used in our metabolic and surgical department as a way to ameliorate inadequate blood supply in patients suffering from diabetic foot (seven patients), painful chronic arterial narrowing, or inoperable occlusions (25 patients). The continuous stimulation by an implantable apparatus (Medtronic model Itrel, Medtronic, Inc., Minneapolis, MN, USA) led to a reduction or disappearance of pain, an improvement in plethysmographic curves, functional performance, and trophic lesions in about 75% of the patients. The system is safe and well-tolerated by patients.
Asunto(s)
Arteriosclerosis/terapia , Angiopatías Diabéticas/terapia , Terapia por Estimulación Eléctrica , Enfermedades del Pie/terapia , Claudicación Intermitente/terapia , Cuidados Paliativos/métodos , Médula Espinal/fisiología , Anciano , Espacio Epidural , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana EdadAsunto(s)
ADN Satélite/sangre , Leucocitos/análisis , Placenta/análisis , Transformación Celular Neoplásica/análisis , Enzimas de Restricción del ADN/metabolismo , ADN Satélite/análisis , ADN Satélite/genética , Femenino , Humanos , Leucemia Linfoide/sangre , Leucemia Linfoide/genética , Leucemia Mieloide/sangre , Leucemia Mieloide/genética , Masculino , EmbarazoRESUMEN
Male and female human placenta DNA was fractionated in an Ag+-Cs2SO4 density gradient. The different fractions along the gradient were analyzed by Hae III endonuclease digestion. Within the main band DNA on the light side a component having a Hae III digestion pattern similar to that of human satellite III DNA has been identified. This component which might be defined as a cryptic satellite accounts for at least 3% of the total human DNA and has a different position than human satellite III in Ag+-Cs2SO4.
