RESUMEN
CONTEXT: With more studies investigating effects of high serum lipid levels, new findings are emerging regarding the damage these biomolecules may cause. AIM: In this study we aimed to find a relation between neuropathy and hypertriglyceridemia in patients with metabolic syndrome (MS). MATERIAL AND METHODS: One hundred and twenty subjects (Ninety subjects with metabolic syndrome and 30 healthy controls) were included in the study. Subjects with MS were divided into three groups. HbA1C levels of the subjects were < 5.7% in group A, ≥ 5.7% - < 6.5% in group B, and ≥ 6.5% - < 8.0% in group C. Pin-Prick test and Semmes- Weinstein Monofilament were used for neurological examination. Electromyography was performed to patients with neuropathy to support the diagnosis. RESULTS: Neuropathy prevalence was found to be higher in the subjects with metabolic syndrome compared to control group. (9.9 %; 16.65 %; 23.31 % vs. 3.3%; in group A, group B, group C vs. healthy control group respectively) (p=0.003 for group A, p=0.0002 for group B, p=0.0002 for group C). There was an association between triglyceride levels and neuropathy in group C. CONCLUSION: Patients with MS may have more neuropathy risk than we estimate.
RESUMEN
A 35-year-old man was admitted to the emergency room with the complaint of weakness of the extremities, which abruptly began in the morning. Only mild generalized muscle weakness was present on physical examination. Laboratory data showed hypokalaemia, elevation of creatinine phosphokinase and serum transaminases. He had been consuming 2.5 litres of soft drink per day for 20 years. There could not be found any metabolic, organic, traumatic and/or pharmacological reason to cause hypokalaemia and rhabdomyolysis other than the long-term and excess consumption of soft drinks. The patient was cured by the replacement of electrolytes and the avoidance of drinking soft drinks.