RESUMEN
UNLABELLED: The complexity of the clinical, biochemical, hystochemical and immunologic aspects of the intervertebral disk, along with its molecular biology, justifies the object of our study on the extracellular matrix modifications in lumbar disk hernias and their impact on patient quality of life. MATERIAL AND METHOD: The research lot was composed of 50 patients, aged between 18 and 73, who have undergone lumbar disk hernia surgery. MMP-9 (metalloproteinase-9) and TIMP-1 (tissue inhibitor of matrix metalloprotease 1) have been dosed in order to study the modifications on extracellular disk matrix, and quality of life assessment was carried out both in pre-operatory and post-operatory periods. CONCLUSIONS: Patients may prevent the appearance of degenerative processes of the intervertebral disk with care and responsibility by controlling their weight, avoiding intense physical activities and ceasing to smoke.
Asunto(s)
Matriz Extracelular/metabolismo , Degeneración del Disco Intervertebral/patología , Disco Intervertebral/patología , Vértebras Lumbares/patología , Adolescente , Adulto , Anciano , Matriz Extracelular/enzimología , Humanos , Disco Intervertebral/enzimología , Degeneración del Disco Intervertebral/enzimología , Vértebras Lumbares/enzimología , Metaloproteinasa 9 de la Matriz/metabolismo , Persona de Mediana Edad , Calidad de Vida , Factores de Riesgo , Inhibidor Tisular de Metaloproteinasa-1/metabolismo , Adulto JovenRESUMEN
The authors present the case of a patient with ocular pain and visual impairment after an ocular trauma. The ophthalmologic exam and the complementary exams show atypical aspects of the traumatic ocular pathology.
Asunto(s)
Lesiones Oculares/complicaciones , Neoplasias del Ojo/diagnóstico , Hipema/diagnóstico , Hipema/etiología , Neoplasias Meníngeas/diagnóstico , Meningioma/diagnóstico , Anciano , Diagnóstico Diferencial , Neoplasias del Ojo/complicaciones , Neoplasias del Ojo/patología , Neoplasias del Ojo/cirugía , Femenino , Glaucoma/etiología , Humanos , Hipema/complicaciones , Hipema/cirugía , Neoplasias Meníngeas/complicaciones , Neoplasias Meníngeas/patología , Neoplasias Meníngeas/cirugía , Meningioma/complicaciones , Meningioma/patología , Meningioma/cirugía , Resultado del Tratamiento , Baja Visión/etiologíaRESUMEN
The present paper analyzed the indications and surgical treatment in 505 patients with lesions of the mitral valve. 350 lesions were of rheumatic nature and 148 with nonrheumatic etiology. 31 patients with infectious endocarditis with mitral localization were operated; 3 deaths and 56 cases wits aggravation of the lesions after endocarditis with a mortality of 6%, were recorded. The severity factors, the complications and characteristics of the intervention in these patients were analyzed. 48 patients had dysfunctions of the mechanical prosthesis with disk and 11 with Edwards Carpentier's prosthesis. The dysfunction types, the diagnosis methods and the evolution were investigated. 16 emergency cases with dysfunctions of the prostheses were operated wits good results. The cooperation among cardiologist, surgeon, explorer and anesthesiologist is an essential condition for the best solution of the new and complex pathology.