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Indian J Tuberc ; 64(2): 144-146, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28410699

RESUMEN

Rifampicin (RFP) and pyrazinamide (PZA) are the primary anti-tubercular drugs with a considerably safe profile. However, none of the drugs are without adverse reactions. They both can lead to a variety of adverse effects including life-threatening anaphylaxis. We report an interesting and possibly the first case of concurrent hypersensitivity to two primary anti-tubercular treatment (ATT) drugs. Hypersensitivity to RFP and PZA was confirmed in this patient by drug provocation and intradermal skin testing. He improved on alternative ATT regime withdrawing RFP and PZA.


Asunto(s)
Anafilaxia/etiología , Antituberculosos/efectos adversos , Hipersensibilidad a las Drogas/etiología , Pirazinamida/efectos adversos , Rifampin/efectos adversos , Tuberculosis Meníngea/tratamiento farmacológico , Niño , Humanos , Masculino
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