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INTRODUCTION AND HYPOTHESIS: To determine if the classification of obstetric anal sphincter injuries (OASIs) affected clinical and functional outcome and to assess the need for follow-up of 3a tears in secondary care METHODS: Prospective data collection in 255 patients who sustained OASIs during repair with follow-up in a specialist clinic after 6 months. RESULTS: One hundred and thirty-two patients (51.7 %) sustained 3a tears, 81 (31.7 %) 3b tears, 27 (10.6 %) 3c tears and 15 (5.8 %) had 4th degree tears. Twenty-three patients (9 %) reported symptoms at 6-month follow-up. Eight patients reported anal incontinence of liquid or solid stool. Among patients who sustained 3a tears, 8 patients were symptomatic: 7 had urgency and 1 had flatus incontinence. None of the patients who sustained 3a tears reported incontinence of solid/liquid stool. There appears to be no correlation with scan findings and symptoms at follow up. Most patients are asymptomatic. Urgency of faeces is the commonest symptom. CONCLUSIONS: The vast majority of patients are asymptomatic. The necessity of seeing all these patients in secondary care for follow-up needs to be questioned. With effective primary care follow-up, there may be a place to follow up patients with 3a tears in the community during the routine 6-week postnatal check and refer the symptomatic patients to the hospital for further review.
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Canal Anal/lesiones , Incontinencia Fecal/etiología , Incontinencia Fecal/cirugía , Complicaciones del Trabajo de Parto , Adulto , Cirugía Colorrectal , Femenino , Estudios de Seguimiento , Procedimientos Quirúrgicos Ginecológicos , Humanos , Embarazo , Estudios Retrospectivos , Atención Secundaria de Salud , Resultado del TratamientoRESUMEN
OBJECTIVE: To investigate the effect of pregnancy and delivery on anal continence, sensation, manometry, and sphincter integrity. STUDY DESIGN: Two hundred eighty-six nulliparous women in the third trimester completed a symptom questionnaire and underwent anorectal sensation and manometric evaluations. Three months postpartum, 161 women returned and the questionnaires and investigations were repeated together with anal endosonographic examinations. RESULTS: The prevalence of fecal urgency before, during, and after pregnancy was 1%, 9.4%, and 10.5%, respectively; the prevalence of anal incontinence before, during, and after pregnancy was 1.4%, 7.0%, and 8.7%, respectively. Vaginal delivery, particularly instrumental, resulted in a decrease in anal squeeze pressures (P =.015) and resting pressures (P =.002) but had no effect on anal sensation. Postpartum anal endosonographic examination revealed sphincter disruption in 38% of women. There was no relationship between symptoms and anal manometry, sensation, or sphincter integrity. Vaginal delivery (P <.0001) and perineal trauma (P <.001) were significantly associated with sphincter defects. CONCLUSION: Vaginal delivery is associated with a decrease in anal pressures and increased anal sphincter trauma but has no effect on anal sensation. These changes were not related to anal symptoms.
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Canal Anal/fisiopatología , Parto Obstétrico/efectos adversos , Incontinencia Fecal/etiología , Canal Anal/lesiones , Canal Anal/inervación , Enfermedades del Ano/diagnóstico por imagen , Enfermedades del Ano/etiología , Enfermedades del Ano/fisiopatología , Cesárea/efectos adversos , Parto Obstétrico/métodos , Incontinencia Fecal/fisiopatología , Femenino , Flatulencia , Humanos , Manometría , Periodo Posparto , Embarazo , Presión , Estudios Prospectivos , Factores de Riesgo , Sensación , Encuestas y Cuestionarios , UltrasonografíaRESUMEN
OBJECTIVE: To evaluate the feasibility of a new technique of primary overlap anal sphincter repair instead of end-to-end repair. SETTING: A teaching hospital and a district general hospital. METHODS: Between June 1995 and November 1996, two obstetricians repaired 32 anal sphincters ruptured during vaginal delivery. A ruptured internal sphincter was repaired separately and the torn ends of the external sphincter were overlapped and sutured with 3/0 polydioxanone sulphate sutures (Ethicon, Edinburgh, UK). MAIN OUTCOME MEASURES: Bowel function, clinical assessment, anal endosonography and manometry performed at a mean of 140 days after delivery. RESULTS: Eight percent of the women experienced incontinence of flatus. Fifteen percent had persistent sonographic external sphincter defects, and 44% had internal sphincter defects. The maximum mean resting pressure was 58 mmHg (range 37-135) and the mean maximum incremental squeeze pressure 54 mmHg (range 8-104). None had defaecatory difficulty and no complications were encountered with the new technique of repair. CONCLUSIONS: Reservations regarding the feasibility of the overlap technique of primary repair are unfounded, as both subjective and objective outcomes are favourable compared with other studies using end-to-end approximation. A multicentre randomised study of the overlap vs end-to-end repair technique is now planned.
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Canal Anal/lesiones , Canal Anal/cirugía , Parto Obstétrico/efectos adversos , Incontinencia Fecal/cirugía , Adolescente , Adulto , Canal Anal/diagnóstico por imagen , Procedimientos Quirúrgicos del Sistema Digestivo/métodos , Endosonografía , Estudios de Factibilidad , Incontinencia Fecal/etiología , Femenino , Estudios de Seguimiento , Humanos , Embarazo , Rotura/diagnóstico por imagen , Rotura/cirugíaRESUMEN
The aim of this study was to assess the magnitude of the morbidity following radical surgery for early stage cervical cancer. We performed a retrospective survey of all women who had undergone a radical hysterectomy and lymphadenectomy between the months of July 1995 and December 1996 inclusive at either the Royal Marsden or St George's Hospital (n =38), using a detailed questionnaire on bladder, ano-rectal and sexual function, both before and after treatment. Sixteen women (44.4%) received adjuvant radiotherapy. The mean interval between surgery and inquiry was 16.4% months (range 8-25 months). The mean age at the time of surgery was 40.5 years. Thirty-six out of 38 women contacted responded (94.7%). Overall 33 women (91.7%) reported new bladder, ano-rectal or sexual symptoms. Complaints of urinary incontinence, particularly of urge incontinence, and of voiding difficulties increased significantly after surgery (P <0.05). However, only 5.3% of women had sought treatment. Tenesmus increased significantly (P <0.05), while increases in diarrhoea and faecal incontinence were not statistically significant (P =0.051). Although 12.9% of women stated an improvement in their sex lives, 54.8% thought that their sex life was worse after treatment, and 12.9% of women had ceased sexual activity altogether. Of women of childbearing age 53.8% felt adversely affected by their loss of fertility. Bladder, ano-rectal and sexual symptoms are very common following radical hysterectomy for cervical cancer, with adverse effect on quality of life, and persist into the second year after treatment.
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OBJECTIVE: To determine whether periurethral collagen is an effective, safe and practical day-case procedure to control genuine stress incontinence (urethral sphincter incompetence) in the elderly female. DESIGN: Prospective longitudinal study using subjective and objective outcome measures with long term follow up. SETTING: A teaching hospital tertiary referral centre. SAMPLE: Thirty-two women over 65 years of age with a urodynamic diagnosis of genuine stress incontinence. RESULTS: At one year, 22 women (79%) were subjectively cured or improved, and 14 (50%) were objectively cured; at two years, 18 (69%) and 14 (54%), respectively. Symptoms of urgency, urge incontinence, frequency and nocturia improved, while voiding difficulty remained unchanged. Brief urinary retention was encountered in seven women. No long term side effects or complications were encountered. Urodynamic studies suggest that collagen works by preventing premature bladder neck opening through physical stress, rather than by obstruction. This would account for the slight increase in functional urethral length. CONCLUSIONS: Contigen collagen is a simple and effective day case procedure as an alternative to major surgery and is without significant morbidity or complication. It is ideal for the elderly.
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Colágeno/uso terapéutico , Incontinencia Urinaria de Esfuerzo/terapia , Anciano , Anciano de 80 o más Años , Atención Ambulatoria , Colágeno/administración & dosificación , Colágeno/efectos adversos , Femenino , Humanos , Inyecciones , Estudios Longitudinales , Estudios Prospectivos , Incontinencia Urinaria de Esfuerzo/fisiopatología , Micción , UrodinámicaRESUMEN
OBJECTIVE: To assess the role of urodynamics in the prediction and assessment of outcome and analysis of the mechanism of cure for stress incontinence using periurethral collagen as our treatment model. DESIGN: Prospective longitudinal study. SETTING: A teaching hospital tertiary referral centre. PATIENTS: Sixty women with genuine stress incontinence. RESULTS: The objective cure rate was 54% (n = 54) at 12 months. Subtracted cystometry, urethral electrical conductivity and bladder neck excursion measurements did not predict cure. A low pre-injection maximum urethral closure pressure adversely affects outcome (31 cmH2O (success) vs 19 cmH2O (failure), P = 0.004); all women with a maximum urethral closure pressure > 39 cmH2O were rendered dry. Urethral pressure profilometry can analyse mechanism of cure. Total profile length, stress maximum urethral closure pressure, stress functional urethral length and pressure transmission ratio in the first quarter of urethral length were increased in successful cases (P < 0.05), and rest maximum urethral and maximum urethral closure pressures, area under rest profile and pressure transmission ratio in the second quarter of urethral length were increased in failed cases (P < 0.02). CONCLUSIONS: In successful cases the increased area and pressure transmission ratio in the first quarter of the functional urethral length suggest that collagen placement occurs at the bladder neck or proximal urethra. Cure appears to be due to prevention of bladder neck opening during stress and not obstruction. In addition the cephalad elongation of the urethra caused by collagen probably accounts for the increased abdominal pressure transmission in the first quarter of the urethra. In failures, there is an increased length and increased area to peak pressure suggesting collagen is deposited more distally. This study confirms the role of certain urethral pressure profilometry variables in the prediction and analysis of mechanism of cure.
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Colágeno/uso terapéutico , Incontinencia Urinaria de Esfuerzo/terapia , Urodinámica , Adulto , Anciano , Anciano de 80 o más Años , Colágeno/administración & dosificación , Femenino , Estudios de Seguimiento , Humanos , Estudios Longitudinales , Persona de Mediana Edad , Presión , Estudios Prospectivos , Resultado del Tratamiento , Incontinencia Urinaria de Esfuerzo/fisiopatologíaRESUMEN
Alterations in the hormonal milieu associated with the menstrual cycle appear to influence the dynamic interaction between the bladder and urethra as well as detrusor function, probably because of the common embryological origin of the lower genital and urinary tracts. In this retrospective study we investigated the effect of the menstrual cycle on cystometric diagnosis. A retrospective case note review of 687 consecutive patients attending the urogynecology unit of St Georges University Hospital, a tertiary referral center, was carried out. The study group comprised 57 women with regular menstrual periods. In both patients whose symptoms were adversely affected premenstrually and those whose symptoms were not influenced by the menstrual cycle, the majority of normal cystometric diagnoses were made in the luteal phase: 45.5% vs. 25% (P < or = 0.002) and 38.5% vs. 4.8% (P < or = 0.05), respectively. Diagnoses of genuine stress incontinence, detrusor instability and mixed genuine stress incontinence and detrusor instability were most frequently made in the follicular phase of the cycle. More normal cystometric diagnoses were made in the influenced group (36.8%) than in the uninfluenced group (21%) (P < 0.02). The results of this preliminary study indicate that the timing of cystometric evaluation may influence the detection of a positive diagnosis. The luteal phase may not be the correct time to make an accurate diagnosis, especially in patients whose symptoms are influenced by their menstrual cycle.
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Ciclo Menstrual , Incontinencia Urinaria/diagnóstico , Incontinencia Urinaria/fisiopatología , Micción/fisiología , Adulto , Femenino , Humanos , Persona de Mediana Edad , Estudios Retrospectivos , Incontinencia Urinaria de Esfuerzo/diagnóstico , Incontinencia Urinaria de Esfuerzo/fisiopatología , Sistema Urinario/fisiopatología , UrodinámicaRESUMEN
In this prospective case controlled study 16 premenopausal women with documented irritable bowel syndrome were recruited from the gastroenterology clinic and 16 premenopausal controls without symptoms of irritable bowel syndrome were recruited from the gynaecology clinic. All women answered a standardised bowel and urinary symptom questionnaire and underwent twin channel subtracted cystometry. Women with irritable bowel syndrome also underwent oesophageal balloon distension studies for perception and pain. Oesophageal and bladder sensory thresholds were compared. Urinary frequency and urgency and the urodynamic finding of detrusor instability were significantly more common in women with irritable bowel syndrome (P < 0.05). We were unable to demonstrate a relationship between first sensation of bladder fullness and oesophageal perception or between maximum bladder capacity and oesophageal pain thresholds. These findings suggest that there is an irritable bladder in the irritable bowel syndrome and support the concept that irritable bowel syndrome is part of a generalised disorder of smooth muscle.
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Enfermedades Funcionales del Colon/complicaciones , Enfermedades de la Vejiga Urinaria/complicaciones , Adulto , Estudios de Casos y Controles , Femenino , Humanos , Dimensión del Dolor , Estudios Prospectivos , Umbral Sensorial , Trastornos Urinarios/etiología , UrodinámicaRESUMEN
For centuries the structure and function of the pelvic floor and anal sphincter have remained enigmatic. Great strides made in new imaging techniques over the last decade has enabled a better understanding of this complex and dynamic structure. We can now explore pelvic floor dysfunction.
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Parto Obstétrico/efectos adversos , Incontinencia Fecal/etiología , Incontinencia Urinaria/etiología , Prolapso Uterino/etiología , Canal Anal/fisiopatología , Incontinencia Fecal/fisiopatología , Femenino , Humanos , Diafragma Pélvico/fisiopatología , Embarazo , Incontinencia Urinaria/fisiopatología , Prolapso Uterino/fisiopatologíaRESUMEN
OBJECTIVE: To assess the short- and medium-term efficacy of periurethral collagen injection in women with urethral sphincter incompetence and to determine if urodynamic variables can elucidate the mechanism of action. PATIENTS AND METHODS: Sixty women (mean age 64 years, range 20-90) with genuine stress incontinence received periurethral collagen injections under local anaesthesia; 55 had undergone previous continence surgery. A total of three injection sessions were allowed. Subjective and urodynamic assessments were obtained at 1, 3, 6, 12 and 24 months after injection to evaluate success and long-term effects of collagen. RESULTS: Subjective success rates were 86% at 3 months, 77% at 12 months and 68% at 24 months. Objective cure rates were 61% at 3 months, 54% at 12 months and 48% at 24 months. Low urethral pressures and decreased bladder neck mobility did not affect the outcome. Collagen injections significantly increased stress maximum urethral closure pressures and functional urethral length; increase in the latter and clinical assessment of bulking at the time of injection appeared to predict medium-term success. There were some minor early complications and none in the medium-term. CONCLUSIONS: Periurethral collagen injections continued to be effective at the 2-year follow-up, although there was a time-dependent decline. In comparison with more complicated procedures used in patients with previous failed continence surgery, periurethral collagen injection is a simple, acceptable, day case procedure which improves the quality of life in physically fit or frail patients, with few complications.