RESUMEN
Nasal and paranasal malignant tumours account for less than 5% of all head and neck malignancies. Epithelial malignancies overwhelmingly predominate, with squamous cell carcinomas representing the most frequent histological subtype in this location. Soft-tissue sarcomas of the nasal cavity and paranasal sinuses are exceedingly rare. Here, we report two cases of myxoid liposarcomas that occurred in the nasal and paranasal regions, both of which presented diagnostic challenges and could not be diagnosed definitively from intraoperative frozen sections. These cases reinforce the notion that, while they are uncommon, sarcomas in general and liposarcomas in particular should still be considered as part of the differential diagnosis in patients presenting with obstructive symptoms in the nasal and paranasal sinuses.
Asunto(s)
Liposarcoma Mixoide/diagnóstico , Neoplasias de los Senos Paranasales/diagnóstico , Seno Esfenoidal , Anciano , Medios de Contraste , Diagnóstico Diferencial , Femenino , Humanos , Liposarcoma Mixoide/patología , Imagen por Resonancia Magnética/métodos , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia , Neoplasias de los Senos Paranasales/patología , Tomografía Computarizada por Rayos XAsunto(s)
Trastornos Cerebrovasculares/historia , Neurocirugia/historia , Procedimientos Quirúrgicos Vasculares/historia , Isquemia Encefálica/cirugía , Trastornos Cerebrovasculares/cirugía , Descompresión Quirúrgica/historia , Descompresión Quirúrgica/métodos , Predicción , Historia del Siglo XVIII , Historia del Siglo XIX , Historia del Siglo XX , Humanos , Aneurisma Intracraneal/cirugía , Malformaciones Arteriovenosas Intracraneales/cirugía , Neurocirugia/tendencias , Hemorragia Subaracnoidea/cirugía , Procedimientos Quirúrgicos Vasculares/tendencias , Vasoespasmo Intracraneal/cirugíaRESUMEN
OBJECTIVE: To describe the clinical significance of tumor-associated hemorrhage in patients with acoustic neuromas. STUDY DESIGN: Retrospective chart review. SETTING: University-based, tertiary care teaching hospital. PATIENTS: Three patients with acoustic neuromas who experienced symptomatic tumoral bleeding. INTERVENTIONS: Radiographic imaging, surgical removal of tumors, and pathologic analysis. MAIN OUTCOME MEASURES: Patient histories, radiologic characteristics, surgical results, and pathologic findings. RESULTS: Tumoral hemorrhage can occur in patients with acoustic neuromas. These three cases and a review of the world literature suggest that tumor size may be the most important risk factor for tumor-related hemorrhage. CONCLUSION: These findings have implications for those patients with acoustic neuromas who choose not to have surgical removal.
Asunto(s)
Neuroma Acústico/cirugía , Hemorragia Posoperatoria/diagnóstico , Anciano , Femenino , Pérdida Auditiva Sensorineural/diagnóstico , Humanos , Imagen por Resonancia Magnética , Persona de Mediana Edad , Estudios Retrospectivos , Índice de Severidad de la EnfermedadRESUMEN
The brain stem has long lost the designation of "no-man's land." Armed with a detailed knowledge of skull base and parenchymal neuroanatomy, coupled with the advances in intraoperative mapping and monitoring, most intrinsic brain stem cavernous malformations can be resected microsurgically. Success continues to depend on proper patient selection, optimal timing, thorough planning, meticulous technique, and completeness of the resection.
Asunto(s)
Tronco Encefálico/cirugía , Cerebelo/cirugía , Craneotomía/métodos , Hemangioma Cavernoso/cirugía , Neoplasias Infratentoriales/cirugía , Microcirugia/métodos , Humanos , Bulbo Raquídeo/cirugía , Mesencéfalo/cirugía , Planificación de Atención al Paciente , Selección de Paciente , Puente/cirugía , Medición de Riesgo/métodos , Resultado del TratamientoRESUMEN
We report a case of an adult female who developed fulminant hepatic failure (FHF) during the second trimester of pregnancy and underwent a successful living related liver transplantation because no cadaveric donor was available during the development of life-threatening symptoms. A left lateral segment hepatic graft was procured from her brother, whose body weight was similar to hers. Her postoperative course was complicated by bleeding at the biliary anastomosis and subsequently by a biliary leak. Nevertheless, the complications were corrected surgically and the patient recovered well with a good quality of life 5 months after the transplant. This case suggests that living related liver transplantation should be considered more frequently for adult FHF patients. As the window of therapeutic opportunity is narrow for the dramatic condition of FHF, wide acceptance of this procedure will be of great benefit for the patients suffering from FHF.
Asunto(s)
Encefalopatía Hepática/cirugía , Trasplante de Hígado , Donadores Vivos , Donantes de Tejidos , Adulto , Femenino , Humanos , Embarazo , Complicaciones del Embarazo/cirugía , Tasa de Supervivencia , Resultado del TratamientoRESUMEN
Revascularization is an important component of treatment for complex aneurysms that cannot be directly clipped and instead require parent vessel occlusion. A consecutive series of 61 patients with 63 aneurysms requiring cerebral revascularization is presented. Aneurysms were located along the petrous internal carotid artery (ICA) (n = 5), the cavernous ICA (n = 16), the supraclinoid ICA (n = 12), the middle cerebral artery (n = 17), the anterior cerebral artery (n = 4), the vertebral artery/posterior inferior cerebellar artery (n = 5), and the midbasilar artery (n = 4). Aneurysms were treated by direct clipping (n = 8), trapping (n = 28), proximal vessel occlusion (n = 9), distal vessel occlusion (n = 1), excision (n = 15), and thrombotic occlusion (n = 2). Revascularization was performed with petrous to supraclinoid ICA bypass (n = 12), superficial temporal artery to middle cerebral artery bypass (n = 15), superficial temporal artery to middle cerebral artery bypass with saphenous graft (n = 5), superficial temporal artery to superior cerebellar artery bypass (n = 4) long saphenous bypass (n = 11), in situ bypass (n = 3), and primary reanastomosis (n = 13). Fifty-seven patients (93%) had good outcomes, and one patient died (surgical mortality, 2%). This experience demonstrates that revascularization can be performed with low morbidity and mortality. We think that the cumulative risks of not performing revascularization in patients who tolerate ICA balloon occlusion exceed the surgical risk of revascularization. We therefore favor revascularization in patients with complex aneurysms treated by surgical arterial occlusion.
Asunto(s)
Isquemia Encefálica/cirugía , Revascularización Cerebral/métodos , Aneurisma Intracraneal/cirugía , Complicaciones Posoperatorias/etiología , Adolescente , Adulto , Anciano , Anastomosis Quirúrgica/métodos , Isquemia Encefálica/diagnóstico por imagen , Isquemia Encefálica/mortalidad , Enfermedades de las Arterias Carótidas/diagnóstico por imagen , Enfermedades de las Arterias Carótidas/mortalidad , Enfermedades de las Arterias Carótidas/cirugía , Arteria Carótida Interna/diagnóstico por imagen , Arteria Carótida Interna/cirugía , Angiografía Cerebral , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Aneurisma Intracraneal/diagnóstico por imagen , Aneurisma Intracraneal/mortalidad , Masculino , Persona de Mediana Edad , Examen Neurológico , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/mortalidad , Tasa de Supervivencia , Resultado del TratamientoAsunto(s)
Malformaciones Arteriovenosas Intracraneales/clasificación , Arteria Carótida Externa/patología , Duramadre/irrigación sanguínea , Hueso Etmoides/irrigación sanguínea , Humanos , Malformaciones Arteriovenosas Intracraneales/terapia , Embolia y Trombosis Intracraneal/terapia , Masculino , Persona de Mediana Edad , Arteria Oftálmica/patología , Piamadre/irrigación sanguínea , Grado de Desobstrucción VascularRESUMEN
Although uncommon, the achondroplastic dwarf (AD) may become the victim of multiple trauma, presenting special challenges for the emergency department (ED) physician. Traditional management of airway, breathing, circulation, and neurological disability is altered by the unique anatomic features of achondroplasia. Despite facial abnormalities observed in the AD, orotracheal and nasotracheal intubation are usually accomplished without particular difficulty; however, abnormalities of the base of the skull and cervical spine make hyperextension of the neck especially hazardous in these patients. The lungs are functionally normal, although vital capacity is decreased and thoracic case abnormalities and abdominal obesity impair lung expansion. Vascular access in the AD is difficult. Peripheral access is difficult because of excessive subcutaneous fat, whereas central venous access is complicated by neck, chest wall, and spinal abnormalities that obscure commonly used anatomic landmarks. Major neurological syndromes observed in ADs are hydrocephalus, cervical medullary compression, and thoracolumbar stenosis. The ED physician should recognize these syndromes, their potential to produce neurological disability, and their unique implications for trauma.
Asunto(s)
Acondroplasia/complicaciones , Medicina de Emergencia , Traumatismo Múltiple/complicaciones , Fracturas Óseas/complicaciones , Hematoma Epidural Craneal/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Traumatismo Múltiple/terapia , Huesos Pélvicos/lesionesRESUMEN
The earliest surgical procedures on the brain stem parenchyma were directed at sectioning specific fiber pathways to alleviate pain. Subsequently, some tumors, abscesses, and vascular lesions that displace rather than invade the parenchyma have been successfully removed. Future advances depend on the ability to preserve and restore neural function in operated tissue.