RESUMEN
We made a comparative survey of the poliovirus antibodies (anti-poliovirus type 1, anti-poliovirus type 2 and anti-poliovirus type 3) and the measles antibodies in malnourished but completely vaccinated children (37) and control children (34). The age range was 10 months to 5 years. Immunization in children with protein-energy malnutrition was low for both vaccines. Seroprevalence rates of the polio 1, polio 2, polio 3 antibodies and the measles antibodies in the control group were 94.1%, 97.1%, 91.2% and 82.4% respectively. In malnourished children the respective rates were in some cases significantly lower being: 40.5% (P = 0.001), 59.5% (P = 0.001), 40.5% and 35.1%. Malnutrition is a major determinant of the humoral response to oral polio and measles vaccines and must be given due consideration to prevent vaccination failure.
Asunto(s)
Trastornos de la Nutrición del Niño/complicaciones , Sarampión/prevención & control , Poliomielitis/prevención & control , Desnutrición Proteico-Calórica/complicaciones , Vacunación/normas , Distribución por Edad , Anticuerpos Antivirales/sangre , Formación de Anticuerpos , Estudios de Casos y Controles , Niño , Trastornos de la Nutrición del Niño/sangre , Trastornos de la Nutrición del Niño/inmunología , Preescolar , Femenino , Humanos , Esquemas de Inmunización , Lactante , Masculino , Sarampión/complicaciones , Sarampión/epidemiología , Virus del Sarampión/inmunología , Marruecos/epidemiología , Poliomielitis/complicaciones , Poliomielitis/epidemiología , Poliovirus/inmunología , Desnutrición Proteico-Calórica/sangre , Desnutrición Proteico-Calórica/inmunología , Estudios Seroepidemiológicos , Distribución por Sexo , Insuficiencia del TratamientoRESUMEN
We made a comparative survey of the poliovirus antibodies [anti-poliovirus type 1, anti-poliovirus type 2 and anti-poliovirus type 3] and the measles antibodies in malnourished but completely vaccinated children [37] and control children [34].The age range was 10 months to 5 years. Immunization in children with protein-energy malnutrition was low for both vaccines. Seroprevalence rates of the polio 1, polio 2, polio 3 antibodies and the measles antibodies in the control group were 94.1%, 97.1%, 91.2% and 82.4% respectively. In malnourished children the respective rates were in some cases significantly lower being: 40.5% [P = 0.001], 59.5% [P = 0.001], 40.5% and 35.1%. Malnutrition is a major determinant of the humoral response to oral polio and measles vaccines and must be given due consideration to prevent vaccination failure
