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J Reprod Immunol ; 143: 103243, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33157499

RESUMEN

A primigravid woman with Covid-19 related respiratory insufficiency was admitted into a tertiary Intensive Care Unit at 23 3/7 weeks' gestation. Highly sensitive flow cytometry of peripheral leukocytes indicated significantly suppressed naïve T- and B-cell compartments. The suppressed immune cell responses led us keep the initially started administration of corticosteroids for fetal and maternal indication at a low dose. After three weeks her B-cell response peaked, SARS-CoV-2 was cleared and clinical improvement ensued a week later. At 28 weeks' gestation, a son of 1570 g was born by cesarean section. She was extubated two days postpartum and discharged from hospital 5.5 weeks postpartum.


Asunto(s)
Linfocitos B/inmunología , COVID-19/diagnóstico , Complicaciones Infecciosas del Embarazo/diagnóstico , Embarazo/inmunología , Insuficiencia Respiratoria/diagnóstico , SARS-CoV-2/fisiología , Linfocitos T/inmunología , Adulto , COVID-19/inmunología , Cesárea , Cuidados Críticos , Femenino , Citometría de Flujo , Número de Embarazos , Humanos , Terapia de Inmunosupresión
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