Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials.

Introduction: So far, Auditory Event-Related Potential (AERP) features have been used to characterize neural activity of patients with tinnitus. However, these EEG patterns could be used to evaluate tinnitus evolution as well. The aim of the present study is to propose a methodology based on AERPs to evaluate the effectiveness of four acoustic therapies for tinnitus treatment. Methods: The acoustic therapies were: (1) Tinnitus Retraining Therapy (TRT), (2) Auditory Discrimination Therapy (ADT), (3) Therapy for Enriched Acoustic Environment (TEAE), and (4) Binaural Beats Therapy (BBT). In addition, relaxing music was included as a placebo for both: tinnitus sufferers and healthy individuals. To meet this aim, 103 participants were recruited, 53% were females and 47% were males. All the participants were treated for 8 weeks with one of these five sounds, which were moreover tuned in accordance with the acoustic features of their tinnitus (if applied) and hearing loss. They were electroencephalographically monitored before and after their acoustic therapy, and wherefrom AERPs were estimated. The sound effect of acoustic therapies was evaluated by examining the area under the curve of those AERPs. Two parameters were obtained: (1) amplitude and (2) topographical distribution. Results: The findings of the investigation showed that after an 8-week treatment, TRT and ADT, respectively achieved significant neurophysiological changes over somatosensory and occipital regions. On one hand, TRT increased the tinnitus perception. On the other hand, ADT redirected the tinnitus attention, what in turn diminished the tinnitus perception. Tinnitus handicapped inventory outcomes verified these neurophysiological findings, revealing that 31% of patients in each group reported that TRT increased tinnitus perception, but ADT diminished it. Discussion: Tinnitus has been identified as a multifactorial condition highly associated with hearing loss, age, sex, marital status, education, and even, employment. However, no conclusive evidence has been found yet. In this study, a significant (but low) correlation was found between tinnitus intensity and right ear hearing loss, left ear hearing loss, heart rate, area under the curve of AERPs, and acoustic therapy. This study raises the possibility to assign acoustic therapies by neurophysiological response of patient.

Mexican validation of the International Affective Digitized Sounds second edition (IADS-2) and additional sounds.

Affective stimuli have been extensively used in emotion research for a better understanding of emotion regulation. Sound ratings, specifically non-verbal sounds, are biased by demographic indicators such as sex and nationality. Therefore, it is crucial to characterize sounds prior to their use in emotion research. This study aims to validate the IADS-2 database and additional sounds in a sample from the Mexican population. Three hundred twenty-nine participants born and raised in Mexico remotely listened to 174 sounds in monophonic format. They rated sounds according to the valence-arousal-dominance model using the Self-Assessment Manikin test. Results positively correlated to those of previous studies. Sex differences were observed only in dominance between female and male groups, contrary to the results from Portuguese, American and Japanese validations. Geographic region analysis demonstrated differences in arousal, indicating the need for additional research on occident and south regions. Furthermore, when conducting affective research, headphones and audio quality should be considered, primarily to reduce variability due to audio-related aspects, and to avoid changes in emotional experience. Finally, this study supports the feasibility of remote affective sound experiments over the internet as reported in previous research.

Data on electroencephalographic activity while exposed to pink noise modified by the frequency responses of three headphone models.

The data described in this article refers to the experimental paradigm where subjects listened to the same pink noise modified by the frequency responses of three headphone models while their brain responses were recorded by means of electroencephalography. Six types of data are described: 1) pink noise sounds with a length of 2.73 s used for the experimental paradigm; 2) electrophysiological recordings, 29 in the first session and 25 in the last session recorded for five minutes; text files with 3) electrode positions and 4) information to identify physiological data and headphone group; 5) a table with technical specifications of the physical headphone model used in the experiment; and 6) a figure summarizing the experimental design. The information in this work can be used to compare the electrical activity of the brain in acoustic treatments where headphones are a key element to meet the therapeutic effect.