[Efficacy and tolerance of coamoxiclav in community-acquired lower respiratory tract infections in children]. / 'Effektivnost' i perenosimost' amoksitsillin/potassium klavulanata pri lechenii detel s vnebol'nichnol infektsiel nizhnikh dykhatel'nykh putel.

Amoxyclav (amoxycillin/potassium clavulanate, A/PC) was used in the treatment of 55 children with acute bronchitis and pneumonia. The drug was administered in a dose of 20-40 mg/kg body weight a day in 3 portions. The treatment course was 4 to 10 days. The treatment was performed under careful clinicoroent-genologic control. The clinical picture of the disease in the children was characterized by a moderate process which made it possible to treat the children as outpatients. The clinical efficacy amounted to 90.5 per cent. The isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus and Haemophilus influenzae proved to be susceptible to A/PC. It may be used as the 1st class agent in the treatment of children with lower respiratory tract infection.

[Neuro-ultrasonography in the assessment of perinatal lesions of the brain in high-risk children at birth and at 3 months of age]. / Neirosonografiia v otsenke perinatal'nykh porazhenii golovnogo mozga u detei vysokoi gruppy riska pri rozhdenii i v 3-mesiachnom vozraste.

As many as 135 children belonging to the group at high risk underwent neurosonography to assess the neuropsychic status in the early neonatal period and at an age of three months. A high rate of perinatal brain injuries was established as was a close relationship between the gestation age of the child, on the one hand and the character and intensity of the injury, on the other one. It has been revealed that the combination of deep immaturity and severe ante-intranatal hypoxia predetermines almost 100% injury of the brain structures, bringing about the formation of organic pathology and impairment of the psychoneurologic development of these children by the age of 3 months.