Ultrasound as a triaging tool for the diagnosis of malaria and typhoid in a resource constrained setting: A proposed frame-work.

INTRODUCTION: Ultrasound has proven to have great potentials in the diagnosis and work-up of patients affected by tropical diseases. Its role in the diagnosis of malaria and typhoid abounds, but its value as a triaging tool in a resource-constrained settings is indistinct. Our review aimed is aimed at assessing the utility of ultrasound in diagnosis and prognosis of malaria and typhoid. MATERIALS AND METHOD: Extensive literature search was conducted using the PubMed electronic database, for original peer reviewed articles in English language within 1964-2023. Keywords like "malaria", "typhoid", "S. Typhi", "Salmonella Typhi", "enteric fever", "ultrasound", "sonography" and "ultrasonography" were searched, using Boolean operators such as (OR, AND) applying the following filters (English, Human). A systematic synthesis of the literature was done. RESULT: Our initial search yielded 749 potentially relevant references out of which 55 were found to be eligible. Organs assessed include the liver, spleen, kidneys, intestines, mesenteric lymph nodes, among others. For malaria, pathognomonic conditions like splenic enlargement, hepatomegaly, renal abnormalities as well as mesenteric lymph nodes and intestinal wall thickening in patients with typhoid fever. CONCLUSION: Ultrasound by experienced clinicians adds significantly to the diagnosis and work-up of patients with malaria and typhoid fever. However, it is important to note that ultrasound alone may not be sufficient for definitive diagnosis as laboratory tests may still be required for confirmatory diagnosis. IMPLICATION FOR PRACTICE: This study provide information on ultrasound in diagnosis of Malaria and typhoid by evaluating the morphological changes in abdominal and other organs of the body. This can be a guide to clinicians and other healthcare providers for early diagnosis and work-up of patients in endemic areas where resources are scarce.

Bonn call for action and the unfinished task of radiation protection of children and adolescents in low and middle-income countries: A focus on Sub-Saharan Africa.

OBJECTIVES: The Bonn call for action, with the theme: "Setting the scene for the next decade," was declared over nine years ago to strengthen radiation protection in medicine. This study reviews key actions and activities related to radiation protection of children and adolescents consistent with the Bonn call for action in sub-Saharan Africa to highlight progress and identify existing gaps. KEY FINDINGS: A lot has happened since the declaration of the Bonn call-for-action such as a follow-up conference in 2017 on achieving change in the practice of radiation protection. However, there exists a huge gap that needs to be filled in the radiation protection of children and adolescents in low and middle-income countries particularly sub-Saharan Africa, where limited resources in health compete with radiation protection demands. Some of the gaps that remain are the apparent lack of implementation of the use of referral guidelines and establishment of national and regional diagnostic reference levels for paediatric imaging among others. CONCLUSION: Several strides have been achieved on a global scale for the Bonn call for action, ranging from the justification of medical exposures to the current drive for radiation safety culture in medical imaging. However, several unmet needs for radiation protection for children and adolescents remain such as implementation of referral guidelines for justification and paediatric diagnostic reference levels. IMPLICATIONS FOR PRACTICE: Step up actions and close collaboration is required to strengthen the practice of paediatric radiation protection in low and middle-income countries because children account for a greater proportion of the population and are vulnerable to the negative effects of radiation like possible cancer induction.

Achieving universal access to obstetric ultrasound in resource constrained settings: A narrative review.

OBJECTIVES: The potential benefits and challenges of achieving universal access to obstetric ultrasound services in resource constrained settings were reviewed, with a view to making some recommendations to address the huge burden of avoidable maternal and child morbidity and mortality. KEY FINDINGS: In most resource-poor settings of the world, antenatal ultrasound is available only to a privileged few in urban centres, while the majority of the population living in rural areas have little or no access to diagnostic imaging services. There is also the extreme shortage of sonographers and doctors with specialist training in sonography. A comprehensive regulation must be put in place to achieve maximum benefits and to ensure quality assurance; appropriate use and application of ethics and training must be comprehensive. CONCLUSION: Ultrasound service provision, in resource-scarce settings, has the potential to improve access and quality of health care services in areas like the point of care ultrasound service provision and in the fields of obstetrics and gynaecology. A comprehensive regulation must be put in place to achieve maximum benefits and to ensure quality assurance. IMPLICATIONS FOR PRACTICE: Making ultrasound technology available and affordable in resource scare settings has the potential to improve access to diagnostic imaging services and reduce avoidable maternal and child death in resource constrained settings.