Asunto(s)
Antígenos HLA/análisis , Embarazo/inmunología , Líquido Amniótico/inmunología , Línea Celular , Femenino , Fertilización In Vitro , Sangre Fetal/inmunología , Antígenos HLA-A/análisis , Antígenos HLA-B/análisis , Antígenos HLA-C/análisis , Antígenos HLA-G , Antígenos de Histocompatibilidad Clase I/análisis , Humanos , Técnicas para Inmunoenzimas , Valores de Referencia , SolubilidadRESUMEN
To determine whether chronic exposure to airport noise affects children, a study was conducted of the physical growth of children, aged 5-13 years, from two communities, one exposed to airport noise (n = 148) and another, not exposed (n = 102). Ten standard anthropometric measurements were made according to U.S. Health Examination Survey guidelines, and information on the social and biological characteristics of each family was collected in interviews. Hotelling's T2-tests were performed comparing the noise-exposed and nonnoise-exposed samples. There was no significant difference between the sample for measurements of social and biological characteristics of the families (including socioeconomic status and maternal reproductive history). Parental anthropometrics differed significantly (T2 = 24.32, P = 0.0001) as did child anthropometrics (T2 = 21.01, P = 0.032). For the child anthropometrics, noise-exposed children's slightly smaller measures of body bulk, together with their larger facial breadths, contributed to the significant T2. When the entire sample (n = 250) was analyzed by multiple linear regression, noise exposure was a significant predictor only of male triceps and subscapular skinfolds. For these two variables, and most other anthropometrics, however, the beta coefficients were negative for both sexes. In order to include information on the covariance structure among all variables, a canonical correlation analysis was performed. Noise exposure loaded negatively on the third canonical variate and was paired with positively loaded measures of body bulk. Taken together, the three analyses suggest that while there is some evidence for a slight effect of airport noise on measures of body bulk for males in this sample, most measures of postnatal growth for both males and females were unaffected by the noise levels experienced.