Incorporating biodiversity responses to land use change scenarios for preventing emerging zoonotic diseases in areas of unknown host-pathogen interactions.

The need to reconcile food production, the safeguarding of nature, and the protection of public health is imperative in a world of continuing global change, particularly in the context of risks of emerging zoonotic disease (EZD). In this paper, we explored potential land use strategies to reduce EZD risks using a landscape approach. We focused on strategies for cases where the dynamics of pathogen transmission among species were poorly known and the ideas of "land-use induced spillover" and "landscape immunity" could be used very broadly. We first modeled three different land-use change scenarios in a region of transition between the Cerrado and the Atlantic Forest biodiversity hotspots. The land-use strategies used to build our scenarios reflected different proportions of native vegetation cover, as a proxy of habitat availability. We then evaluated the effects of the proportion of native vegetation cover on the occupancy probability of a group of mammal species and analyzed how the different land-use scenarios might affect the distribution of species in the landscape and thus the risk of EZD. We demonstrate that these approaches can help identify potential future EZD risks, and can thus be used as decision-making tools by stakeholders, with direct implications for improving both environmental and socio-economic outcomes.

Body yield and quality of fresh and post-freezing filet of Nile tilapia (Oreochromis niloticus) genetic groups.

The aim of this study was to evaluate the body yield and quality of fresh and post-freezing filet of male and female fish of inbred and non-inbred AquaAmérica genetic group and the hybrid between the AquaAmérica and Tilamax varieties. Forty fish (20 males and 20 females) of each genetic group were housed in four 48-m3 hapa net cages, getting 120 fish per cage. The fish were housed at 51 days of age and farmed for 269 days. Pre-slaughter weight was higher (P<0.05) in the AquaAmérica × Tilamax males (0.805±0.204 kg) than in the inbred AquaAmérica male (0.643±0.115 kg). Filet yield percentage was higher (P<0.05) in the AquaAmérica × Tilamax males (32.14±4.72%) than in the inbred AquaAmérica (28.15±2.67%) and non-inbred AquaAmérica (29.06±2.80%) males. Head and viscera yield percentages, pH, color values (L*, a* and b*), shear force, drip loss and cooking loss did not differ significantly between the genetic groups and sexes. Alterations in meat quality were observed after freezing. In conclusion, inbreeding in the AquaAmérica variety resulted in reduced slaughter weight for males; AquaAmérica × Tilamax males have a higher filet yield; and filet quality is not influenced by crossing, inbreeding, or sex, but is changed after freezing.

South Atlantic explosive cyclones in 2014-2015: study employing NCEP2 and MERRA-2 reanalyses.

An analysis of explosive cyclone cases was produced by comparing the reanalysis of MERRA-2 (high spatial resolution) and NCEP2 (low spatial resolution) to South Atlantic in the 2014-2015 period. A total of 51 cases were found, of which 49 were detected by the first reanalysis and 33 by the second (2 cases identified by NCEP2 were not identified by MERRA-2). Spring was the dominant season in the formation of the cases in both reanalyses. It was observed that most systems are formed preferentially eastward of a preexisting trough at higher levels, while others are formed under an almost zonal upper airstream. This difference is more evident in the NCEP2. It was also diagnosed that the MERRA-2 shows more clearly the diffluence in the 250 hPa flow. The analysis of the composite fields revealed a negative horizontal tilt of the trough in 500 hPa, influenced by intense convection as the system develops. Besides, it pointed to a more pronounced jet stream in intense explosive cyclones and more prominent diffluence in non-intense cases. Since the NCEP2 reanalysis detected fewer cases (and only 2 intense) than MERRA-2, it was considered that the former is less suited to the analysis of this type of event.

Left atrial minimum volume is better correlate of left atrial dysfunction by two-dimensional strain

BACKGROUND: The analysis of left atrial (LA) function can add important information to the understanding of cardiovascular diseases. Therefore, to assess its functioning the use of volumetric measurements is adopted. The maximum LA volume is the most echocardiography parameter used, however, some studies demonstrated that minimum LA volume is better to correlate with atrial dysfunction. Purpose: The purpose of this study was compare the accuracy of the phasic volumes of the left atrium in determining LA dysfunction identified by the two-dimensional strain. METHODS: This observational, cross-sectional study admitted 109 participants with diagnosis of acute coronary syndrome non-ST-segment elevation. The exams were performed within 72 hours of admission. LA volume was defined by the mean of measurements performed in the four and two-chamber apical windows using Simpson's method. The phasic volumes of the left atrium were measured using an electrocardiogram synchronized with the device. Reservoir LA strain less than 21% was the cut off to LA dysfunction. RESULTS: The phasic LA volume variables analyzed were maximal (LAVMAX), minimal (LAVMIN) and before atrial contraction (LAVBAC) volume, and each variable indexed for body surface (LAVIMAX, LAVIMIN and LAVIBAC). Therefore, a Roc curve was generated for each volume variable to assess which would be more accurate in predicting left atrial dysfunction. The Youden index was used to determine the cutoff point for each one of them. The areas under the Roc curves were: 0.83 (LAVIMIN), 0.81 (LAVMIN), 0.78 (LAVBAC), 0.76 (LAVIMAX), 0.74 (LAVIBAC) and 0.71 (LAVMAX). CONCLUSION: This study concluded that phasic volumes were good determinants of left atrial dysfunction identified by 2D strain. The minimum left atrial volume was the better correlated with left atrial dysfunction.

Left atrial minimum volume is better correlate of left atrial dysfunction by two-dimensional strain

BACKGROUND: The analysis of left atrial (LA) function can add important information to the understanding of cardiovascular diseases. Therefore, to assess its functioning the use of volumetric measurements is adopted. The maximum LA volume is the most echocardiography parameter used, however some studies demonstrated that minimum LA volume is better to correlate with atrial dysfunction. PURPOSE: The purpose of this study was compare the accuracy of the phasic volumes of the left atrium in determining LA dysfunction identified by the two-dimensional strain. METHODS: This observational, cross-sectional study admitted 109 participants with diagnosis of acute coronary syndrome non-ST-segment elevation. The exams were performed within 72 hours of admission. LA volume was defined by the mean of measurements performed in the four and two-chamber apical windows using Simpson's method. The phasic volumes of the left atrium were measured using an electrocardiogram synchronized with the device. Reservoir LA strain less than 21% was the cut off to LA dysfunction. RESULTS: The phasic LA volume variables analyzed were maximal (LAVMAX), minimal (LAVMIN) and before atrial contraction (LAVBAC) volume, and each variable indexed for body surface (LAVIMAX, LAVIMIN and LAVIBAC). Therefore, a Roc curve was generated for each volume variable to assess which would be more accurate in predicting left atrial dysfunction. The Youden index was used to determine the cutoff point for each one of them. The areas under the Roc curves were: 0.83 (LAVIMIN), 0.81 (LAVMIN), 0.78 (LAVBAC), 0.76 (LAVIMAX), 0.74 (LAVIBAC) and 0.71 (LAVMAX). CONCLUSION: This study concluded that phasic volumes were good determinants of left atrial dysfunction identified by 2D strain. The minimum left atrial volume was the better correlate with left atrial dysfunction.

AMAZONIA CAMTRAP: A data set of mammal, bird, and reptile species recorded with camera traps in the Amazon forest.

The Amazon forest has the highest biodiversity on Earth. However, information on Amazonian vertebrate diversity is still deficient and scattered across the published, peer-reviewed, and gray literature and in unpublished raw data. Camera traps are an effective non-invasive method of surveying vertebrates, applicable to different scales of time and space. In this study, we organized and standardized camera trap records from different Amazon regions to compile the most extensive data set of inventories of mammal, bird, and reptile species ever assembled for the area. The complete data set comprises 154,123 records of 317 species (185 birds, 119 mammals, and 13 reptiles) gathered from surveys from the Amazonian portion of eight countries (Brazil, Bolivia, Colombia, Ecuador, French Guiana, Peru, Suriname, and Venezuela). The most frequently recorded species per taxa were: mammals: Cuniculus paca (11,907 records); birds: Pauxi tuberosa (3713 records); and reptiles: Tupinambis teguixin (716 records). The information detailed in this data paper opens up opportunities for new ecological studies at different spatial and temporal scales, allowing for a more accurate evaluation of the effects of habitat loss, fragmentation, climate change, and other human-mediated defaunation processes in one of the most important and threatened tropical environments in the world. The data set is not copyright restricted; please cite this data paper when using its data in publications and we also request that researchers and educators inform us of how they are using these data.

A portrait of Brazilian primary care: municipal expenditure and infrastructure in Brazilian municipalities. / Retrato da atenção básica no Brasil: gastos e infraestrutura em municípios brasileiros.

The paper presents the relationship between the allocation of financial resources and the type of local basic health infrastructure in an initial sample of 5,570 Brazilian municipalities. This is an explanatory research using multiple correspondence analysis and quantile regression between expenditure/control variables and the type of structure of PHC Units. The correspondence between the type and the representative variables of expenditure shows that inferior typologies are related to lower per capita expenditure in these variables, and vice versa. Quantile regression showed a positive relationship with the type of infrastructure in the two cycles evaluated. There is evidence that expenditure variables are positively related to infrastructure, which allows us to understand that allocating more resources leads to better infrastructure. Results point to the need to improve the governance of financial resources for health, as municipalities with lower socioeconomic indicators have an infrastructure in the lower categories. We can conclude that there are multiple actors, and the various criteria for allocating and decentralizing resources bring about difficulties of coordination and integration between the entities, restricting the appropriate prioritization in the distribution of resources.

O trabalho apresenta a relação entre a alocação de recursos financeiros e a tipologia da infraestrutura básica local de saúde em amostra inicial de 5.570 municípios do Brasil. Trata-se de uma pesquisa explicativa com uso da análise de correspondência múltipla e regressão quantílica entre variáveis de gastos/controle e a tipologia da estrutura das Unidades Básicas de Saúde. As correspondências entre a tipologia e variáveis representativas dos gastos mostram que tipologias inferiores estão relacionadas com menores gastos per capita nessas variáveis, e vice-versa. A regressão quantílica apresentou relação positiva com a tipologia da infraestrutura nos dois ciclos avaliados. Há evidência das variáveis de gasto estarem relacionadas, de maneira positiva, à infraestrutura, permitindo entender que alocar mais recursos leva a melhor infraestrutura. No entanto, há a necessidade de melhoria na governança dos recursos financeiros da saúde, pois municípios com indicadores socioeconômicos inferiores têm infraestrutura nas categorias inferiores. Conclui-se que há grande multiplicidade de atores e os múltiplos critérios para alocação e descentralização de recursos trazem dificuldades de coordenação e integração entre os entes, restringindo a adequada priorização na alocação dos recursos.

Wild meat consumption in tropical forests spares a significant carbon footprint from the livestock production sector.

Whether sustainable or not, wild meat consumption is a reality for millions of tropical forest dwellers. Yet estimates of spared greenhouse gas (GHG) emissions from consuming wild meat, rather than protein from the livestock sector, have not been quantified. We show that a mean per capita wild meat consumption of 41.7 kg yr-1 for a population of ~ 150,000 residents at 49 Amazonian and Afrotropical forest sites can spare ~ 71 MtCO2-eq annually under a bovine beef substitution scenario, but only ~ 3 MtCO2-eq yr-1 if this demand is replaced by poultry. Wild meat offtake by these communities could generate US$3M or US$185K in carbon credit revenues under an optimistic scenario (full compliance with the Paris Agreement by 2030; based on a carbon price of US$50/tCO2-eq) and US$1M or US$77K under a conservative scenario (conservative carbon price of US$20.81/tCO2-eq), representing considerable incentives for forest conservation and potential revenues for local communities. However, the wild animal protein consumption of ~ 43% of all consumers in our sample was below the annual minimum per capita rate required to prevent human malnutrition. We argue that managing wild meat consumption can serve the interests of climate change mitigation efforts in REDD + accords through avoided GHG emissions from the livestock sector, but this requires wildlife management that can be defined as verifiably sustainable.

A portrait of Brazilian primary care: municipal expenditure and infrastructure in Brazilian municipalities. / Retrato da atenção básica no Brasil: gastos e infraestrutura em municípios brasileiros.

The paper presents the relationship between the allocation of financial resources and the type of local basic health infrastructure in an initial sample of 5,570 Brazilian municipalities. This is an explanatory research using multiple correspondence analysis and quantile regression between expenditure/control variables and the type of structure of PHC Units. The correspondence between the type and the representative variables of expenditure shows that inferior typologies are related to lower per capita expenditure in these variables, and vice versa. Quantile regression showed a positive relationship with the type of infrastructure in the two cycles evaluated. There is evidence that expenditure variables are positively related to infrastructure, which allows us to understand that allocating more resources leads to better infrastructure. Results point to the need to improve the governance of financial resources for health, as municipalities with lower socioeconomic indicators have an infrastructure in the lower categories. We can conclude that there are multiple actors, and the various criteria for allocating and decentralizing resources bring about difficulties of coordination and integration between the entities, restricting the appropriate prioritization in the distribution of resources.

O trabalho apresenta a relação entre a alocação de recursos financeiros e a tipologia da infraestrutura básica local de saúde em amostra inicial de 5.570 municípios do Brasil. Trata-se de uma pesquisa explicativa com uso da análise de correspondência múltipla e regressão quantílica entre variáveis de gastos/controle e a tipologia da estrutura das Unidades Básicas de Saúde. As correspondências entre a tipologia e variáveis representativas dos gastos mostram que tipologias inferiores estão relacionadas com menores gastos per capita nessas variáveis, e vice-versa. A regressão quantílica apresentou relação positiva com a tipologia da infraestrutura nos dois ciclos avaliados. Há evidência das variáveis de gasto estarem relacionadas, de maneira positiva, à infraestrutura, permitindo entender que alocar mais recursos leva a melhor infraestrutura. No entanto, há a necessidade de melhoria na governança dos recursos financeiros da saúde, pois municípios com indicadores socioeconômicos inferiores têm infraestrutura nas categorias inferiores. Conclui-se que há grande multiplicidade de atores e os múltiplos critérios para alocação e descentralização de recursos trazem dificuldades de coordenação e integração entre os entes, restringindo a adequada priorização na alocação dos recursos.

Ethmoid glomangioma and oncogenic osteomalacia: a case report.

BACKGROUND: Glomangioma is a benign tumor of mesenchymal origin, derived from the glomus body. It is responsible for the thermal regulation of the dermis. The occurrence of oncogenic osteomalacia related to glomangioma is rare. Only two cases have been reported thus far. CASE PRESENTATION: A 32-year-old female, Brazilian, presented diffuse pain, during pregnancy, that developed progressively, limiting her mobility. Imaging showed a femoral neck fracture, and rheumatological laboratory examination showed hypophosphatemia. Also, the patient reported episodes of epistaxis during childhood and recurrence along with progressively right nasal obstruction. Endoscopic resection of the tumor was performed, and immunohistochemistry was conclusive for glomangioma. This case report describes the third case in which endonasal endoscopic surgery resulted in a favorable outcome. CONCLUSION: This case of glomangioma-induced oncogenic osteomalacia suggests that surgeons and clinicians should consider sinonasal tumors as a differential diagnosis of osteomalacia, and endonasal endoscopic surgery should be a possible curative resection.

Comparing explosive cyclogenesis cases of different intensities occurred in Southern Atlantic.

Six events of explosive cyclogenesis occurred in the south Atlantic were compared using reanalysis data and satellite water vapor imagery. Cases of different intensities (weak, moderate and strong) occurred during 2014 summer season and 2012 winter season were studied. Despite the similarities the tropopause anomaly was more prominent and vertical movements were stronger in the strong cyclogenesis cases. The tropopause anomalies behind the cold front and ahead of the warm front appear only in the mature stage of the weak and moderate cases while in the strong case it is already evident and more intense behind the cold front since the beginning of the cycle. In all the cases confluence of the jet streams took place at higher levels forming a jet streak with difluence occurring downstream and the cyclone beginning in the exit region. The trajectories of the cyclones were in the southeast direction but longer and more meridional in the strong cases. The results indicated the baroclinicity of the region as the main mechanism for the development of these cyclones as well as the amplitude of the upper level jet stream perturbation. Furthermore, all the explosive cyclones developed following the Shapiro & Keyser cyclone conceptual model.

Retrato da atenção básica no Brasil: gastos e infraestrutura em municípios brasileiros / A portrait of Brazilian primary care: municipal expenditure and infrastructure in Brazilian municipalities

Resumo O trabalho apresenta a relação entre a alocação de recursos financeiros e a tipologia da infraestrutura básica local de saúde em amostra inicial de 5.570 municípios do Brasil. Trata-se de uma pesquisa explicativa com uso da análise de correspondência múltipla e regressão quantílica entre variáveis de gastos/controle e a tipologia da estrutura das Unidades Básicas de Saúde. As correspondências entre a tipologia e variáveis representativas dos gastos mostram que tipologias inferiores estão relacionadas com menores gastos per capita nessas variáveis, e vice-versa. A regressão quantílica apresentou relação positiva com a tipologia da infraestrutura nos dois ciclos avaliados. Há evidência das variáveis de gasto estarem relacionadas, de maneira positiva, à infraestrutura, permitindo entender que alocar mais recursos leva a melhor infraestrutura. No entanto, há a necessidade de melhoria na governança dos recursos financeiros da saúde, pois municípios com indicadores socioeconômicos inferiores têm infraestrutura nas categorias inferiores. Conclui-se que há grande multiplicidade de atores e os múltiplos critérios para alocação e descentralização de recursos trazem dificuldades de coordenação e integração entre os entes, restringindo a adequada priorização na alocação dos recursos.

Abstract The paper presents the relationship between the allocation of financial resources and the type of local basic health infrastructure in an initial sample of 5,570 Brazilian municipalities. This is an explanatory research using multiple correspondence analysis and quantile regression between expenditure/control variables and the type of structure of PHC Units. The correspondence between the type and the representative variables of expenditure shows that inferior typologies are related to lower per capita expenditure in these variables, and vice versa. Quantile regression showed a positive relationship with the type of infrastructure in the two cycles evaluated. There is evidence that expenditure variables are positively related to infrastructure, which allows us to understand that allocating more resources leads to better infrastructure. Results point to the need to improve the governance of financial resources for health, as municipalities with lower socioeconomic indicators have an infrastructure in the lower categories. We can conclude that there are multiple actors, and the various criteria for allocating and decentralizing resources bring about difficulties of coordination and integration between the entities, restricting the appropriate prioritization in the distribution of resources.

O estágio de atendimento nos anos iniciais: experiência com plantão psicológico / Psychological practicum by early years students: experience through psychological attendance / La practica de atendimiento en los años iniciales: la experiencia de estudiantes en jornada psicológica

Este artigo discute a experiência de quatro plantonistas em seu primeiro estágio de atendimento em projeto de plantão em clínica-escola universitária, no terceiro semestre do curso. Os relatos revelaram como o plantão se organizou para cuidar destes estudantes, bem como cada estagiário conduziu-se de modo singular ao longo do estágio. Evidenciou-se que o plantão abarca múltiplos dizeres dos estudantes como possibilidade de propiciar um aprender pela experiência. Convocados pela atenção psicológica dos supervisores, os saberes dos plantonistas mostraram-se incorporados em seu agir, surgindo nas narrativas contadas. A formação surgiu como formar-ação, pela aprendizagem significativa como via privilegiada de constituição do saber de ofício do psicólogo. A investigação destacou a relevância deste estágio ocorrer nos semestres inicias pelo modo como estagiários apresentaram uma compreensão pertinente de plantão nesta perspectiva. Manifesta-se a urgência da clínica-escola contemplar projetos que diferenciem serviços de atenção às demandas da clientela.

The present investigation intended to explore how four students experienced their first practicum in the university project of Psychological Attendance, from the second year of the Psychology Course. It revealed how that practicum is organized to take care of the student, as well as how the project showed itself as singular, allowing the students' narrative for this investigation. It was possible to comprehend how the psychological attendance opened to the participants many possibilities to learn through experience, by learning in action. At the same time, by the supervisors' careful psychological attention, the students referred how they incorporated such knowledge in their acting by their reflexions about the experiences at the supervisions as well as with clients. It revealed the possibility of significative learning in action as pertinent to comprehend the meaning of psychologist's attention, even when the practicum occurs for Psychology freshmen students. This investigation points to the urgency to changes in the curriculum of Psychology courses in order to contemplate projects that open new possibilities, directing them to the clients' actual needs.

Este articulo discute la experiencia de cuatro estudiantes que iniciaron su primera practica de atendimiento en jornada, en el tercer semestre de la carrera. Los relatos revelan como se organizo la jornada para cuidar del estudiante. Por otro lado, el proyecto mostro como cada practicante se comporto de manera singular a lo largo de la practica. Se evidencio que la jornada abarca múltiples posicionamientos de los estudiantes, como posibilidad de propiciar un aprendizaje por medio de la experiencia. Convocados por la atención psicológica de supervisores, los saberes de los participantes de la jornada se muestran incorporados en su forma de actuar, siendo difícil hablar sobre esto, pero surgiendo en las reflexiones e historias contadas. En este sentido la formación surgió como formaraccion, por el aprendizaje significativo como vía privilegiada de la constitución del saber del oficio del psicólogo. Así, la investigación destacó la relevancia de que esta practica sea realizada en los semestres iniciales por el modo como los practicantes presentan una comprensión pertinente de la jornada en esta perspectiva. Por esa vía se manifiesta la urgencia de la clínica-escuela, de contemplar proyectos de practicas que diferencian servicios de atención a las demandas de la clientela, en su amplitud.

Laryngeal Mucosa Alterations in Mice Model of Gastroesophageal Reflux: Effects of Topical Protection.

OBJECTIVES/HYPOTHESIS: The objectives of this study were to evaluate laryngeal inflammation and mucosal integrity in a murine model of reflux disease and to assess the protective effects of topical agents including alginate, hyaluronic acid, and cashew gum. STUDY DESIGN: Animal study. METHODS: A surgical murine model of reflux disease was evaluated at 3 or 7 days postsurgery, and laryngeal samples were collected to measure inflammation (wet weight and myeloperoxidase [MPO]) and mucosal integrity (transepithelial resistance [TER] and mucosal permeability to fluorescein). Additional groups of animals were administered one of several topical agents (alginate, hyaluronic acid, or cashew gum) daily, and laryngeal inflammation and mucosal integrity were evaluated at 3 days postsurgery. RESULTS: At 3 days, and not 7 days postsurgery, we observed increased laryngeal wet weight and MPO, decreased laryngeal TER, and increased laryngeal mucosa permeability. Alginate partially decreased laryngeal inflammation (wet weight and not MPO) and dramatically improved laryngeal mucosal integrity. Conversely, hyaluronic acid eliminated the inflammation; however, it had no effect on laryngeal mucosal integrity impairment. Cashew gum eliminated laryngeal inflammation as well as the impairment in laryngeal mucosal integrity. CONCLUSIONS: This study shows that a surgical model of reflux disease induced laryngeal inflammation and impairment in laryngeal barrier function. These observed alterations were partially attenuated by alginate and hyaluronic acid and completely reversed by cashew gum. LEVEL OF EVIDENCE: NA Laryngoscope, 2020.

Hydroquinone exposure alters the morphology of lymphoid organs in vaccinated C57Bl/6 mice.

The influenza is a common viral infection that can be fatal, especially in high-risk groups such as children, pregnant women, elderly, and immune-deficient individuals. Vaccination is the most efficient approach to prevent the spreading of viral infection and promote individual and public health. In contrast, exposure to environmental pollutants such as cigarette smoke reduces the efficacy of vaccination. We investigated whether chronic exposure to hydroquinone (HQ), the most abundant compound of the tobacco particulate phase, could impair the adaptive immune responses elicited by influenza vaccination. For this, adult male C57BL/6 mice were daily exposed to either nebulized HQ or PBS for 1 h for a total of eight weeks. At weeks 6 and 8, the mice were primed and boosted with the trivalent influenza vaccine via IM respectively. Although the HQ exposure did not alter the body weight of the mice and the biochemical and hematological parameters, the pollutant increased the oxidative stress in splenocytes of immunized animals, modified the morphology of spleen follicles, and augmented the size of their lymph nodes. The lymphoid organs of HQ-exposed mice presented a similar number of vaccine-specific IgG-secreting cells, titers of vaccine-specific total IgG, and respective subclasses. Transcriptome studies with HQ, benzene, or cigarette smoke exposure were also analyzed. The genes up-regulated upon pollutant exposure were associated with neutrophil migration and were shown to be co-expressed with antibody-secreting cell genes. Therefore, these findings suggest that HQ exposure may trigger an immune-compensatory mechanism that enhances the humoral responses induced by influenza vaccination.

Neotropical carnivores: a data set on carnivore distribution in the Neotropics

Mammalian carnivores are considered a key group in maintaining ecological health and can indicate potential ecological integrity in landscapes where they occur. Carnivores also hold high conservation value and their habitat requirements can guide management and conservation plans. The order Carnivora has 84 species from 8 families in the Neotropical region: Canidae; Felidae; Mephitidae; Mustelidae; Otariidae; Phocidae; Procyonidae; and Ursidae. Herein, we include published and unpublished data on native terrestrial Neotropical carnivores (Canidae; Felidae; Mephitidae; Mustelidae; Procyonidae; and Ursidae). NEOTROPICAL CARNIVORES is a publicly available data set that includes 99,605 data entries from 35,511 unique georeferenced coordinates. Detection/non‐detection and quantitative data were obtained from 1818 to 2018 by researchers, governmental agencies, non‐governmental organizations, and private consultants. Data were collected using several methods including camera trapping, museum collections, roadkill, line transect, and opportunistic records. Literature (peerreviewed and grey literature) from Portuguese, Spanish and English were incorporated in this compilation. Most of the data set consists of detection data entries (n = 79,343; 79.7%) but also includes non‐detection data (n = 20,262; 20.3%). Of those, 43.3% also include count data (n = 43,151). The information available in NEOTROPICAL CARNIVORES will contribute to macroecological, ecological, and conservation questions in multiple spatio‐temporal perspectives. As carnivores play key roles in trophic interactions, a better understanding of their distribution and habitat requirements are essential to establish conservation management plans and safeguard the future ecological health of Neotropical ecosystems. Our data paper, combined with other largescale data sets, has great potential to clarify species distribution and related ecological processes within the Neotropics. There are no copyright restrictions and no restriction for using data from this data paper, as long as the data paper is cited as the source of the information used. We also request that users inform us of how they intend to use the data.

Hydroquinone exposure alters the morphology of lymphoid organs in vaccinated C57Bl/6 mice

The influenza is a common viral infection that can be fatal, especially in high-risk groups such as children, pregnant women, elderly, and immune-deficient individuals. Vaccination is the most efficient approach to prevent the spreading of viral infection and promote individual and public health. In contrast, exposure to environmental pollutants such as cigarette smoke reduces the efficacy of vaccination. We investigated whether chronic exposure to hydroquinone (HQ), the most abundant compound of the tobacco particulate phase, could impair the adaptive immune responses elicited by influenza vaccination. For this, adult male C57BL/6 mice were daily exposed to either nebulized HQ or PBS for 1 h for a total of eight weeks. At weeks 6 and 8, the mice were primed and boosted with the trivalent influenza vaccine via IM respectively. Although the HQ exposure did not alter the body weight of the mice and the biochemical and hematological parameters, the pollutant increased the oxidative stress in splenocytes of immunized animals, modified the morphology of spleen follicles, and augmented the size of their lymph nodes. The lymphoid organs of HQ-exposed mice presented a similar number of vaccine-specific IgG-secreting cells, titers of vaccine-specific total IgG, and respective subclasses. Transcriptome studies with HQ, benzene, or cigarette smoke exposure were also analyzed. The genes up-regulated upon pollutant exposure were associated with neutrophil migration and were shown to be co-expressed with antibody-secreting cell genes. Therefore, these findings suggest that HQ exposure may trigger an immune-compensatory mechanism that enhances the humoral responses induced by influenza vaccination.

Growth curve of pacu and the patinga hybrid farmed in a semi-intensive system / Curva de crescimento do pacu e do híbrido patinga produzidos em sistema semi-intensivo

The growth curve is a tool that can be used to determine the performance potential of fish at different ages. The aim of this study was to evaluate the growth curve of pacu (P. mesopotamicus) and the patinga hybrid (P. mesopotamicus × P. brachypomus) cultivated in a semi-intensive system. In the initial phase of the experiment, the pacu and patinga fish weighed 32.6 ± 7.5 g and 24.9 ± 7.1 g, respectively. The Gompertz model was adopted to describe the growth curve. At the end of the experiment, body weight, standard length, head length, body height and body width did not differ significantly between the pacu (625.9 g; 25.6 cm; 7.2 cm; 12.1 cm; 4.5 cm) and the patinga hybrid (727.1 g; 27.3 cm; 7.6 cm; 13.2 cm; 4.9 cm). The asymptotic value (parameter A), relative growth rate (parameter B), and age at the inflection point (parameter C) of the growth curve of the two species were similar for weight and for the evaluated morphometric traits. The asymptotic values obtained for weight in the pacu and the patinga hybrid were 1212.0 g and 1348.0 g, respectively. The growth curve of the patinga hybrid is similar to that of pacu, contrasting with the belief of many fish farmers.

A curva de crescimento possibilita determinar o potencial de desempenho dos peixes em diferentes idades. O objetivo do estudo foi avaliar a curva de crescimento do pacu (P. mesopotamicus) e do híbrido patinga (P. mesopotamicus x P. brachypomus) produzidos em sistema semi-intensivo. Foram utilizados no início do experimento pacu e patinga com peso de 32,6 ± 7,5 g e 24,9 ± 7,1 g, respectivamente. Foi utilizado o modelo Gompertz para descrever a curva de crescimento. No final do experimento, o peso corporal, comprimento padrão, comprimento da cabeça, altura do corpo e largura do corpo não diferiram significativamente entre o pacu (625,9 g; 25,6 cm; 7,2 cm; 12,1 cm; 4,5 cm) e o híbrido patinga (727,1g; 27,3 cm; 7,6 cm; 13,2 cm; 4,9 cm). O valor assintótico (parâmetro A), taxa de crescimento relativo (parâmetro B) e idade no ponto de inflexão (parâmetro C) da curva de crescimento do pacu e patinga foram semelhantes para peso e características morfométricas avaliadas. O valor assintótico obtido para peso no pacu e no híbrido patinga foi de 1212,0 g e 1348,0 g, respectivamente. O híbrido patinga apresenta curva de crescimento semelhante ao pacu, contrastando com a crença de muitos piscicultores.