Esporte paralímpico: análise da produção de teses e dissertações dos programas de pós-graduação em Educação Física / Paralympic sport: analysis of production of thesis and dissertations of graduate programs in Physical Education

O esporte para pessoas com deficiência tem paulatinamente ganhado visibilidade no campo midiático e acadêmico. Este estudo, de caráter descritivo e interpretativo, teve como objetivos (1) Levantar as teses e dissertações de cunho qualitativo produzidas pelos programas de pós-graduação em educação física até 2015 que abordam temáticas relacionadas com o esporte paralímpico e que possuem um enfoque nas dimensões socioculturais e pedagógicas desta manifestação esportiva. (2) Correlacionar estes trabalhos com o modelo analítico do esporte proposto por Marchi Jr em seu trabalho intitulado "O esporte ´em cena´: perspectivas históricas e interpretações conceituais para a construção de um modelo analítico. Uma revisão da literatura com recorte temático foi realizada seguindo quatro etapas. A etapa preliminar consistiu no levantamento das teses e dissertações da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) do Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT) produzidas até o ano de 2015, utilizando os descritores "paraolímpico", "paralímpico", "paradesporto", "paraatleta" e "para-atleta". A segunda etapa envolveu a seleção dos trabalhos de acordo com os objetivos do estudo. A terceira etapa consistiu na leitura na íntegra dos trabalhos selecionados. A quarta etapa envolveu o levantamento dos metadados dos trabalhos, técnicas de pesquisa, matrizes teóricas, análises e resultados dos estudos. Com base no modelo analítico utilizado, ficou evidenciado que as dimensões do esporte mais recorrentes nas teses e dissertações analisadas são a educação, o espetáculo e a estética...

Sport for people with disabilities has been gaining increasing visibility in the media and in the academic fi eld. This descriptive and interpretative study had as objectives: (1) To raise the theses and dissertations of a qualitative nature produced by postgraduate programs in physical education up to 2015 that deal with themes related to the Paralympic sport and that have a focus on the sociocultural and pedagogical aspects of this kind of sport. (2) To correlate these works with the analytical model of the sport proposed by Marchi Jr in his work entitled "The sport ´on the scene´: historical perspectives and conceptual interpretations for the construction of an analytical model". A review of the literature with a thematic approach was carried out following four steps: The fi rst step consisted of a survey of the theses and dissertations of the Brazilian Digital Library of Theses and Dissertations (BDTD) of the Brazilian Institute for Information in Science and Technology (IBICT) produced by 2015 using as keywords: "Paralympics", "Paralympic" "parasports" "paraatleta" and "para-athlete". The second step was the selection of the studies according to the research goals. The third stage consisted of reading the entire works that were selected. The last step involved the collection of the studies metadata and of their research techniques, theoretical frameworks, and results. Based on the analytical model used, it was evidenced that the most recurrent dimensions of Paralympic sport that appeared in the theses and dissertations analyzed are education, spectacle and aesthetics....(AU)

CCR5 chemokine receptor gene polymorphisms in ocular toxoplasmosis.

CC chemokine receptor type 5 (CCR5) is a chemokine receptor that influences the immune response to infectious and parasitic diseases. This study aimed to determine whether the CCR5Δ32 and CCR5 59029 A/G polymorphisms are associated with the development of ocular toxoplasmosis in humans. Patients with positive serology for Toxoplasma gondii were analyzed and grouped as 'with ocular toxoplasmosis' (G1: n=160) or 'without ocular toxoplasmosis' (G2: n=160). A control group (G3) consisted of 160 individuals with negative serology. The characterization of the CCR5Δ32 and CCR5 59029 A/G polymorphisms was by PCR and by PCR-RFLP, respectively. The difference between the groups with respect to the mean age (G1: mean age: 47.3, SD±19.3, median: 46 [range: 18-95]; G2: mean age: 61.3, SD±13.7, median: 61 [range: 21-87]; G3: mean age: 38.8, SD±17.9, median: 34 [range: 18-80]) was statistically significant (G1 vs.G2: p-value <0.0001; t=7.21; DF=318; G1 vs.G3: p-value <0.0001; t=4.32; DF=318; G2 vs. G3: p-value <0.0001; t=9.62; DF=318). The Nagelkerke r2 value was 0.040. There were statistically significant differences for the CCR5/CCR5 (p-value=0.008; OR=0.261), AA (p-value=0.007; OR=2.974) and AG genotypes (p-value=0.018; OR=2.447) between G1 and G2. Individuals with the CCR5/CCR5 genotype and simultaneously the CCR5-59029 AA or AG genotypes have a greater risk of developing ocular toxoplasmosis (4% greater), which may be associated with a strong and persistent inflammatory response in ocular tissue.

Resinas compostas: alterações dimensionais em função da composição e do método de irradiação de luz / Resin composites: dimensional changes in relation to composition and polymerization methods

Objetivo: Avaliar e comparar a força de contração de polimerização de duas resinas compostas (microhíbrida e de preenchimento em bloco "bulk fill") utilizando dois métodos de polimerização (uniforme contínua "convencional" e pulso tardio). Material e método: Quarenta corpos de prova (CP) foram confeccionados (6x1x2mm), sendo 20 CP com a resina composta de preenchimento em bloco "bulk fill" x-tra fil (VOCO) e 20 CP com a resina micro-híbrida Filtek Z250 (3M ESPE). Para cada resina composta a ser testada metade dos corpos de prova (10 CP) foram fotopolimerizados pela técnica convencional [40s contínuos] e a outra metade (10 CP) com a técnica de irradiação pulso tardio [5s, seguida de 1 min de intervalo e mais 35s]. A fotopolimerização foi realizada com fonte de luz LED com 1250 mW/cm². A força de contração, em Newtons (N) foi considerada como o valor registrado pela máquina de ensaios, 2 min após o início da aplicação da luz no CP. Os dados obtidos foram submetidos à análise estatística descritiva, ANOVA a dois critérios e Tukey (P<0,05). Resultados: Diferenças estatisticamente significativas foram observadas para as resinas compostas testadas (P<0,001) e para os métodos de polimerização (P=0,001). Conclusões: A técnica de fotopolimerização convencional e a resina composta microhíbrida produziram menor força de contração de polimerização.

Objective: Evaluating and comparing the polymerization contraction force of two composite resins (microhybrid and bulk fill) using two different methods of polymerization (conventional - continuous uniform and late pulse). Material and methods: 40 specimens (CP) were made (6x1x2mm). 20 CP were made with the bulk fill composite resin x-tra fil (VOCO) and 20 CP with the FiltekZ250 (3M ESPE) microhybrid resin. For each composite resin to be tested half of the specimens (10 CP) was photopolymerized by the conventional technique [40s continuous] and the other half (10 CP) by the late pulse irradiation technique [5s, followed by 1 min interval, and 35s]. The photopolymerization was performed with a 1250 mW/cm² LED light source. The force of contraction, in Newtons (N) was considered as the value recorded by the test machine, 2 min after the beginning of the application of the light in the CP. Data were submitted to descriptive statistical analysis, ANOVA at two criteria, and Tukey (P <0.05). Results: Statistically significant differences were observed for the composite resins tested (P <0.001) and for the polymerization methods (P = 0.001). Conclusion: The conventional photopolymerization technique and the microhybrid composite resin produced a smaller polymerization contraction force.

The role of CCR5 in Chagas disease - a systematic review.

Chagas disease is an infection caused by the protozoan Trypanosoma cruzi. The clinical manifestations result from the chronic forms of the disease: indeterminate, cardiac, digestive or mixed. The pathogenesis of this disease is related to the genetic variability of both the parasite and the host with polymorphisms of genes involved in immune response possibly being involved in the variable clinical course. Cytokines play a key role in regulating immune response, in particular chemokines exert a crucial role in the control of leukocyte migration during the host's response to infectious processes. Furthermore, inflammatory cytokines and chemokines have been implicated in the generation of inflammatory infiltrates and tissue damage. The involvement of the CC Chemokine Receptor 5 (CCR5) in leukocyte migration to sites of inflammation has been elucidated and this receptor has been investigated in Chagas disease. Here we review the role of CCR5 in T. cruzi infection as well as its importance in the pathogenesis of the Chagas disease.