RESUMEN
Concentrations of potentially toxic metals were determined in crayfish (Palaemon hastatus) commonly consumed in Nigeria using Atomic Absorption Spectrophotometry. Results revealed that Fe had the highest mean value of 18.88 ± 0.10 µg/g, while Pb had the least (0.91 ± 0.01 µg/g). Cluster analysis showed close inter-element relationships between the metals, indicating similar chemical properties and/or genetic origin. Correlation matrix indicated positive and significant correlations between Cr/Cd, Fe/Cd, Fe/Cr, Pb/Cd, Pb/Fe and Cu/Zn, establishing chemical affinity. Estimated daily intake, target hazard quotient and cancer risk showed that there was no health risk associated with the consumption of the crayfish. Relative risk showed that potential health risk could be attributed only to Cd level. The study concluded that consumption of the crayfish may not pose health risk to human health at the levels of the analysed metals, but should be consumed moderately to prevent bioaccumulation of the metals most importantly Cd.
RESUMEN
BACKGROUND: The aim of this study was to investigate the disorders of sympathetic nervous system in patients with hyperthyroidism using sympathetic skin response (SSR). MATERIAL AND METHODS: Twenty-two newly diagnosed cases with hyperthyroidism were included in the study. The results were compared with those of 20 healthy controls. SSR was recorded with the contralateral electrical stimulation of the median nerve (of the upper extremities) and tibial nerve (of the lower extremities) with active electrodes placed on palms and soles and reference electrodes attached on the dorsal aspects of hands and feet. RESULTS: Ages of the cases with hyperthyroidism and controls ranged between 15-65 years (mean: 46.7 +/- 15.0 years) and 24-62 years (mean: 39.6 +/- 9.8 years) respectively (p > 0.05). In all the control subjects SSR could be obtained, while from the lower extremities of 4 cases with hyperthyroidism (18.0%) SSR could not be elicited. Mean SSR latencies of lower extremities were found significantly longer than control group (p < 0. 05). No difference was detected between mean amplitudes of SSR in upper and lower extremities. CONCLUSION: These findings suggest that SSR is useful for investigation of sympathetic nervous system involvement in cases with hyperthyroidism.
