RESUMEN
Intussusception is a rare occurrence in the adult population with most of the cases seen during the childhood period. Compared with the pediatric intussusceptions, there is more often an underlying cause in adults. Lipoma as a lead point for colonic intussusception is rare. Ultrasound may be helpful in the diagnosis, but computed tomography is more reliably used for differential diagnosis. An adult patient with colo-colonic intussusception diganosed with ultrasound and confirmed with computed tomography is presented.
Asunto(s)
Neoplasias del Ciego/complicaciones , Enfermedades del Colon/etiología , Intususcepción/etiología , Lipoma/complicaciones , Adulto , Neoplasias del Ciego/diagnóstico por imagen , Enfermedades del Colon/diagnóstico por imagen , Femenino , Humanos , Intususcepción/diagnóstico por imagen , Lipoma/diagnóstico por imagen , Tomografía Computarizada por Rayos XRESUMEN
BACKGROUND AND AIMS: Postprandial increase of 5-hydroxytryptamine (5-HT) has been implicated in irritable bowel syndrome (IBS). There is evidence that nitric oxide (NO) may act as a mediator of 5-HT-evoked secretions in the colon. Our aim is to investigate the role of urinary 5-hydroxyindole acetic acid (5-HIAA) and plasma NO levels (with diarrhoea) in IBS patients. METHODS: Nineteen (with constipation) IBS patients (group 1), 22 IBS patients (group 2) and 18 healthy controls (group 3) were included in the study. The diagnosis of IBS was made according to the Rome I Criteria. The urine was collected for determination of 5-HIAA and venous blood was collected from each subject for the measurement of plasma NO levels. RESULTS: The levels of urinary 5-HIAA mmol/day and plasma NO mmol/l of group 1 (22.4 +/- 2.2 and 29.4 +/- 2 respectively) were significantly higher than group 3 (14.2 +/- 2.3 and 21.3 +/- 2.1 respectively) (p = 0.036 and p = 0.019 respectively). The NO level of group 1 was also significantly higher than group 2 (21.8 +/- 1.9) (p = 0.021). The 5-HIAA level of group 1 was higher than group 2 (15.2 +/- 2.1) and the difference was marginally significant (p = 0.055). There was no difference between group 2 and group 3 with respect to 5-HIAA and NO levels. CONCLUSIONS: The results of this preliminary study lend support to the involvement of 5-HT in some symptomatology of diarrhoea predominant IBS. Furthermore, NO may be one of the effector mediators of the 5-HT-induced symptoms in these patients.
Asunto(s)
Ácido Hidroxiindolacético/análogos & derivados , Síndrome del Colon Irritable/sangre , Síndrome del Colon Irritable/orina , Óxido Nítrico/sangre , Serotonina/orina , Adulto , Análisis de Varianza , Distribución de Chi-Cuadrado , Estreñimiento/sangre , Estreñimiento/orina , Diarrea/sangre , Diarrea/orina , Femenino , Humanos , Ácido Hidroxiindolacético/orina , Masculino , Periodo PosprandialAsunto(s)
Adenoma/patología , Granuloma Anular/patología , Neoplasias Cutáneas/patología , Adenoma/complicaciones , Corticoesteroides/administración & dosificación , Biopsia con Aguja , Femenino , Estudios de Seguimiento , Granuloma Anular/complicaciones , Granuloma Anular/tratamiento farmacológico , Humanos , Dermatosis de la Pierna/diagnóstico , Dermatosis de la Pierna/tratamiento farmacológico , Persona de Mediana Edad , Neoplasias Cutáneas/complicaciones , Resultado del TratamientoRESUMEN
We present an ochronotic patient with spondylosis and upper extremity involvement. We also evaluated radiologic findings of joints that were involved and MRI features of the lumbar spine.
Asunto(s)
Ocronosis/diagnóstico , Osteofitosis Vertebral/diagnóstico , Vértebras Torácicas/patología , Estudios de Seguimiento , Mano , Humanos , Articulación de la Rodilla , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Ocronosis/complicaciones , Articulación del Hombro , Osteofitosis Vertebral/complicacionesAsunto(s)
Síndrome de Behçet/tratamiento farmacológico , Síndrome de Behçet/microbiología , Colchicina/efectos adversos , Supresores de la Gota/efectos adversos , Infecciones por Helicobacter/epidemiología , Helicobacter pylori , Adulto , Síndrome de Behçet/patología , Femenino , Mucosa Gástrica/microbiología , Mucosa Gástrica/patología , Humanos , Masculino , PrevalenciaRESUMEN
OBJECTIVE: Scientific evidence of functional interface between the immune and sensory motor systems of the gut and respiratory systems has been reported. In recent studies excess prevalence of bronchial hyper-responsiveness has been shown among patients with irritable bowel syndrome (IBS). The purpose of our study was to investigate the possible relationship between IBS and asthma. METHODS: One hundred thirty-three patients with IBS (108 women, 25 men) and 137 control subjects (105 women, 32 men) were included in this study. Both for IBS and the control group, the mean ages were 41.64+/-9.45 yr and 39.94+/-10.62 yr, respectively. Patients more than 50 yr old, with any organic GI disease, acute respiratory system infection, current or ex-smokers, and patients using drugs affecting smooth muscle and autonomic nervous system were not included in the study. Respiratory symptoms were questioned and pulmonary function tests were performed for every subject. RESULTS: There were 45 (33.8%) and eight (5.8%) subjects with respiratory symptoms in IBS and control groups, respectively (p < 0.0001). Twenty-one (15.8%) patients from the IBS group and two (1.45%) patients from the control group had the diagnosis of asthma according to history, clinical, and PFT findings. There was no statistical difference between two groups with respect to percentage of forced vital capacity and forced expiratory volume in 1 s-to-forced vital capacity. The difference between the two groups in forced expiratory volume in 1 s, flow after 50% of the vital capacity has been exhaled, peak expiratory flow rate, and maximal mid-expiratory flow rate was statistically significant (p < 0.01). CONCLUSION: We found that the prevalence of asthma was more common in the IBS group than in controls. Our finding supports the speculation that asthma and IBS may share common pathophysiological processes.