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Int J Pharm ; 636: 122817, 2023 Apr 05.
Artículo en Inglés | MEDLINE | ID: mdl-36905974

RESUMEN

Pickering emulsions are free from molecular and classical surfactants and are stabilized by solid particles, creating long-term stability against emulsion coalescence. Additionally, these emulsions are both environmentally and skin-friendly, creating new and unexplored sensorial perceptions. Although the literature mostly describes conventional emulsions (oil-in-water), there are unconventional emulsions (multiple, oil-in-oil and water-in-water) with excellent prospects and challenges in skin application as oil-free systems, permeation enhancers and topical drug delivery agents, with various possibilities in pharmaceutical and cosmetic products. However, up to now, these conventional and unconventional Pickering emulsions are not yet available as commercial products. This review brings to the discussion some important aspects such as the use of phases, particles, rheological and sensorial perception, as well as current trends in the development of these emulsions.


Asunto(s)
Sistemas de Liberación de Medicamentos , Piel , Emulsiones/metabolismo , Piel/metabolismo , Absorción Cutánea , Tensoactivos/metabolismo
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