RESUMEN
OBJECTIVE: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status. METHOD: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. IGFBP-3 levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. RESULT: Median serum IGFBP-3 levels in malnourished children were found to be lower i.e. 0.35mcg/mL (minimum-maximum: 0.04-1.52mcg/mL) compared to well-nourished children 1.52ng/mL (minimum-maximum 0.47-3.17mcg/mL). CONCLUSION: Serum IGFBP-3 levels can be used as indicators to assess nutritional status.
Asunto(s)
Trastornos de la Nutrición del Niño , Proteína 3 de Unión a Factor de Crecimiento Similar a la Insulina/sangre , Desnutrición , Estatura , Niño , Trastornos de la Nutrición del Niño/epidemiología , Preescolar , Estudios Transversales , Humanos , Desnutrición/epidemiología , Estado NutricionalRESUMEN
Objective: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status. Method: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. IGFBP-3 levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. Result: Median serum IGFBP-3 levels in malnourished children were found to be lower i.e. 0.35 mcg/mL (minimummaximum: 0.041.52 mcg/mL) compared to well-nourished children 1.52 ng/mL (minimummaximum 0.473.17 mcg/mL). Conclusion: Serum IGFBP-3 levels can be used as indicators to assess nutritional status. (AU)