A technological innovation and economic progress enhancement: an assessment of sustainable economic and environmental management.

This study examines the role of technological innovation and economic progress on environmental pollution by using STRIPAT and EKC theoretical frameworks in 25 developing Asian countries from the period 1998 to 2019. For technological advancement, the energy intensity has been used to gauge how much of the quantity of energy is employed to produce the additional unit of gross domestic product at domestic level. Therefore, the volume of the energy used in the production process is highly important as it is documented through the energy intensity. To capture the impact of innovation, the sum of total patent applications and trademark applications for the sampled countries has been used. This study applied second-generation unit root and panel cointegration techniques to estimate the results. To estimate the long-run relationship of variables and the cross-sectional interdependence, Pedroni Residual and Westerlund Cointegration tests are applied. Further, the Hausman-Taylor-type test has been used to check the efficiency of the pool mean group (PMG). The results of PMG regression confirm the existence of EKC in the developing Asian countries. The results of this study showed that technological development, innovations, and economic progress have the potential to reduce carbon emission and to protect the environment in developing Asian economies. Moreover, the results of error correction model indicate that in case of any external shock, this model will converge towards equilibrium within 64.6 years. The study proposed that a policy framework related to technological innovations should be sustained and the advancement of human capital and research and development should be the primary focus of the developing nations to mitigate the environmental challenges.

The dynamic role of energy security, energy equity and environmental sustainability in the dilemma of emission reduction and economic growth.

This study examines the relationship between energy security, energy equity, and environmental sustainability from the perspective of economic growth and CO2 emissions. For this purpose, this study utilizes the energy trilemma index (ETI) 2018 of the World Energy Council (WEC) to measure, evaluate and assess the energy efficiency of the top ten best-performing countries around the world. This study formulates an interval decision matrix to apply Principal Components Analysis (PCA) by reducing a large set into a small set of underlying variables with comprehensive information. Finally, this study uses the Fuzzy-TOPSIS method to determine the comprehensive ranks of all countries. This study shows that Denmark holds overall first rank in energy efficiency with a score of one in energy security, eleven in energy equity, and seventeen in environmental sustainability. In contrast, Germany has dominated all top ten performers by energy and environmental progress, which cannot be shirker within the UK's social progress concept. Thus, with ceteris paribus, a higher energy price will indicate a higher degree of scarcity of energy sources, encouraging working for cheaper and renewable alternatives and ultimately influencing the energy supply side. Carbon valuation can reduce greenhouse emissions by paying the extra dollar to the enterprise for less emission. It will lead to changing energy consumption structures and make it a cleaner choice for profit maximization.

Managerial policy and economic analysis of wind-generated renewable hydrogen for light-duty vehicles: Green solution of energy crises.

The unconventional energy sources like hydrogen energy have tremendous potential of filling the gap between economic growth and clean energy consumption. A little intention has been made in this regard in the developing economies like Pakistan. This study develops a fusibility analysis to highlight the potential of hydrogen energy source in Pakistan. For this purpose, this study used a hybrid mathematical model that combines the range of wind speed with the log law to push wind power's potential to generate wind hydrogen in Pakistan. The study results indicate that Pakistan has an excellent source to generate hydrogen energy through wind power stations. According to the outcomes, Nooriabad can produce 303.66 million RE/kWh per year through wind energy sources. According to the results, the rest of the seven wind generation sites also can generate enough hydrogen energy. This study also concluded that hydrogen energy has enough sources to meet the demand for light-duty vehicles in Pakistan.

An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement.

OBJECTIVE: To compare the efficacy, in the prevention of venous thromboembolism (VTE), and safety, of rivaroxaban and dabigatran relative to the common comparator enoxaparin. METHODS: Two randomized clinical trials of dabigatran, one after total hip replacement (THR), RE-NOVATE, and one after total knee replacement (TKR), RE-MODEL, were identified as using the same enoxaparin regimen (40 mg once daily given the evening before surgery) and being of comparable duration to two rivaroxaban trials, RECORD1 and RECORD3. Indirect comparisons were performed on both efficacy and safety endpoints. To enable comparisons, symptomatic VTE results were based on the total study duration period, i.e. including the follow-up period. Major bleeding included surgical-site bleeding events. RESULTS: After THR, rivaroxaban 10 mg once daily significantly reduced total VTE and symptomatic VTE relative to dabigatran 220 mg once daily (relative risk 0.34 and 0.19, respectively). After TKR, rivaroxaban significantly reduced total VTE versus dabigatran (relative risk 0.53); symptomatic VTE was not different between dabigatran and rivaroxaban. There was no significant difference in the rates of major bleeding for patients receiving rivaroxaban or dabigatran. CONCLUSIONS: Based on the indirect comparisons, rivaroxaban was estimated to be more efficacious than dabigatran in the prevention of total VTE after THR and TKR. Our analysis relied upon published data for dabigatran and did not have the advantages of more detailed comparative data obtained directly from a randomized trial, as was the case with rivaroxaban. Further comparative research may be of value, but until available our conclusions represent the best available evidence.

Rates, risk factors & methods of self harm among minority ethnic groups in the UK: a systematic review.

BACKGROUND: Studies suggest that the rates of self harm vary by ethnic group, but the evidence for variation in risk factors has not been synthesised to inform preventive initiatives. METHODS: We undertook a systematic literature review of research about self harm that compared at least two ethnic groups in the United Kingdom. RESULTS: 25 publications from 1765 titles and abstracts met our inclusion criteria. There was higher rate of self harm among South Asian women, compared with South Asian men and White women. In a pooled estimate from two studies, compared to their white counterparts, Asian women were more likely to self harm (Relative Risk 1.4, 95%CI: 1.1 to 1.8, p = 0.005), and Asian men were less likely to self harm (RR 0.5, 95% CI: 0.4 to 0.7, p < 0.001). Some studies concluded that South Asian adults self-harm impulsively in response to life events rather than in association with a psychiatric illness. Studies of adolescents showed similar methods of self harm and interpersonal disputes with parents and friends across ethnic groups. There were few studies of people of Caribbean, African and other minority ethnic groups, few studies took a population based and prospective design and few investigated self harm among prisoners, asylum seekers and refugees. CONCLUSION: This review finds some ethnic differences in the nature and presentation of self harm. This argues for ethnic specific preventive actions. However, the literature does not comprehensively cover the UK's diverse ethnic groups.

Psychological distress and chronic obstructive pulmonary disease in the Renfrew and Paisley (MIDSPAN) study.

BACKGROUND: This study examined whether psychological distress might be a predictor of chronic obstructive pulmonary disease (COPD). METHOD: The relation between psychological distress at baseline, measured by the general health questionnaire (GHQ), and chronic bronchitis three years later, as measured by the Medical Research Council (MRC) bronchitis questionnaire and forced expiratory flow in one second (FEV(1)), was examined in 1682 men and 2203 women from the Renfrew and Paisley (MIDSPAN) study. The analyses were run on men and women separately and adjustments were made for age, socioeconomic position, and lung function at baseline (FEV(1)). People with chronic diseases at baseline were then excluded to give a "healthy" baseline cohort. The effect of psychological distress on individual components of the MRC bronchitis questionnaire and FEV(1) was also assessed. RESULTS: In multivariate analyses of the whole cohort baseline psychological distress in women was associated with reduced FEV(1) at follow up (OR 1.31 95% CI 1.0 to 1.73) after adjustment. In women, in the healthy cohort, psychological distress was associated with chronic bronchitis (OR 2.00, 95% CI 1.16 to 3.46), symptoms of bronchial infection (OR 2.14, 95% CI 1.44 to 3.19), symptoms of breathlessness (OR 3.02, 95% CI 1.99 to 4.59), and reduced FEV(1) (OR 1.62, 95% CI 1.13 to 2.32). In men psychological distress predicted symptoms of bronchial infection (OR 2.09, 95% CI 1.28 to 3.42). CONCLUSION: This study supports research suggesting that psychological distress is associated with COPD and shows that psychological distress predicts COPD in women. The robustness of the association and the exact mechanism requires further investigation.

Psychological distress, physical illness and mortality risk.

BACKGROUND: Psychological distress has been associated with an increased risk of overall and disease-specific mortality risk. This study examines whether the length of follow-up time influences mortality risk. METHODS: The associations between psychological distress and all-cause and coronary heart disease mortality were modelled using proportional hazards modelling in a prospective cohort study of 6920 men and women aged 45-64 years. Psychological distress was assessed at baseline using the 30-item General Health Questionnaire (GHQ-30). RESULTS: Psychological distress was associated with a 5-year all-cause mortality (RR 1.68 95% CI 1.07-2.62) and CHD mortality (RR 1.64 95% CI 1.02-2.56) in men after adjustment for sociodemographic and CHD risk factors, but not after further adjustment for baseline physical illness (RR 1.41 95% CI 0.88-2.23) for all-cause mortality (RR 1.39 95% CI 0.88-2.21) for CHD mortality. Psychological distress was not associated with all-cause and CHD mortality at 15- and 20-year follow-up. CONCLUSIONS: Psychological distress is a reflection of baseline physical illness that increases mortality risk. Psychological distress maybe on the causal pathway between physical illness and mortality risk.

Common mental disorder and physical illness in the Renfrew and Paisley (MIDSPAN) study.

OBJECTIVE AND METHODS: The relationship between psychological distress measured by the General Health Questionnaire 30 (GHQ-30) and risk factors for coronary heart disease, angina, electrocardiogram (ECG) abnormalities and chronic sputum was modelled using logistic regression on baseline data from a community study of 15,406 men and women. RESULTS: Psychological distress was associated with low forced expiratory volume (FEV(1)) and low body mass index (BMI) in men, and low systolic blood pressure only in women. There were associations between psychological distress and coronary heart disease and cardiorespiratory outcomes. The associations were particularly strong for angina without ECG abnormalities (Men: OR 3.26, 95% CI 2.52-4.21; Women: OR 2.89, 95% CI 2.35-3.55) and for angina with ECG abnormalities (Men: OR 2.68, 95% CI 2.03-4.52; Women: OR 2.88, 95% CI 1.89-4.39), in both men and women, even after adjusting for classical CHD and cardiorespiratory risk factors. An association between psychological distress and severe chest pain, indicative of previous myocardial infarction, was found in both men and women (Men: OR 1.89, 95% CI 1.44-2.47; Women: OR 1.91, 95% CI 1.48-2.47), respectively, and between psychological distress and ECG ischaemia, but in men only (OR 1.32, 95% CI 1.00-1.76). CONCLUSION: The association between psychological distress and cardiorespiratory outcomes is likely to be a consequence of the pain and discomfort of the symptoms of the illness. Chest pain may also be a symptom of psychological distress. However, psychological distress, as a predictor and possible risk factor increasing the risk of coronary heart disease, cannot be ruled out.