Relationship between Obesity and Periodontal Diseases in Saudi Women (Asir Region): A Prospective Study.

AIM: The present study is undertaken to assess any possible association between obesity and periodontal diseases among Saudi women in Asir region. MATERIALS AND METHODS: A total number of 100 obese subjects in the age group between 16 and 35 years participated in the study. A questionnaire which consisted of anthropometric measurements [neck circumference (NC) ≥ 34 cm for women] and demographic features was used. Periodontal status was assessed for the subjects. RESULTS: The periodontal disease shows significant association with anthropometric measurements (NC ≥ 34 cm for women) and demographic features. CONCLUSION: The findings of this prospective study showed possible relationship between obesity and periodontal disease. CLINICAL SIGNIFICANCE: In view of changing lifestyle with dietary habits, there is a possibility of developing obesity. The results in this research show a direct relationship between obesity and periodontal diseases by measuring body mass index (BMI) and NC in the age group of 16 to 35 years females in Saudi Arabia. Thus, it helps in preventing and managing obesity, especially among youth.

Thermoreversible gel for intrapocket delivery of green tea catechin as a local drug delivery system: An original research.

The periodontal therapies along with systemic antibiotic therapy aim at eliminating the subgingival microbiota to arrest the progression of periodontal diseases. The complete elimination is often difficult, and thus the probability of repopulation after periodontal therapy is also high. The objectives of the study are to develop in situ thermoreversible gelling system of green tea catechins suitable for periodontal pocket administration, which would act as an adjunct to mechanical periodontal therapy. Gel is prepared on a weight basis using a cold process. In vitro drug release pattern is observed through spectrophotometer analysis at 277 nm. The gel is subjected to serial dilution analysis to determine the minimum inhibitory concentration (MIC) and disc diffusion analysis to determine the in vitro antibacterial effectiveness. Release pattern studies showed a complete release of drug from gel occurred by 36 h. A volume of 1.25 mg/ml was determined as MIC required against the periodontal pathogens. Disc diffusion analysis showed a 14 mm zone of inhibition is present around the 75 µl well for all the four species and 12 mm zone of inhibition around the 50 µl well. The advantage of F-127 is its thermoreversible nature that used for in situ gel formulation. Pluronic gel proved to be a promising carrier for prolong and effective release of green tea catechin.

Management of Recurrent Post-partum Pregnancy Tumor with Localized Chronic Periodontitis.

Pregnancy tumor is a benign, hyperplastic lesion of the gingiva, considered to be reactive or traumatic rather than neoplastic in nature. The term pyogenic granuloma is a misnomer as it is not filled with pus or granulomatous tissue histologically. It is multi factorial in nature, which shows an exaggerated response to stimuli such as low grade or chronic irritation, trauma or hormonal variations. Higher levels of sex hormones during pregnancy produce effects on sub gingival microflora, the immune system, the vasculature and specific cells of periodontium which in turn in the presence of local irritants exaggerate the lesion. Since the lesion is clinically indistinguishable from other type of hyperplastic conditions, histological findings are required for proper diagnosis. We present a case report of recurrent pyogenic tumor which showed the evidence of pre-existing localized periodontitis with extensive horizontal bone destruction. The lesion was excised by electrocautery combined with conventional flap procedure after parturition period. During 3 and 6 months follow-up period post-operative healing showed satisfactory results without recurrence.